DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment alphaTry and tmprss9

DIOPT Version :9

Sequence 1:	NP_476771.1	Gene:	alphaTry / 48316	FlyBaseID:	FBgn0003863	Length:	256	Species:	Drosophila melanogaster
Sequence 2:	XP_002940084.3	Gene:	tmprss9 / 100489279	XenbaseID:	XB-GENE-993973	Length:	1151	Species:	Xenopus tropicalis

Alignment Length:	236	Identity:	90/236 - (38%)
Similarity:	121/236 - (51%)	Gaps:	17/236 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 RIVGGSATTISSFPWQISLQRSGSHSCGGSIYSANIIVTAAHCLQSVSASVLQVRAGSTYWSSGG 94
            :||||........|||.||:....|.||.:|.....:|:||||........:....|||..|...
Frog   546 KIVGGLDAVRGEIPWQASLKEGSRHFCGATIIGDRWLVSAAHCFNQTKVDQVTAHMGSTALSGAD 610

  Fly    95 VVAKVSSFK---NHEGYNANTMVNDIAVIRLSSSLSFSSSIKAISLAT---YNPANGASAAVSGW 153
            .:|...|.|   .|..:|..|:..|:||:.|:|||:|:..::.:.|.:   ..|| |....:|||
Frog   611 TIAIKISLKRVIQHPHFNPLTLDFDVAVLELASSLTFNKYVQPVCLPSALQKFPA-GWKCMISGW 674

  Fly   154 GTQSSGSSSIPSQLQYVNVNIVSQSQCASSTYGYGSQIRNTMICAA-ASGK-DACQGDSGGPLV- 215
            |....|:.|.|..||..:|.|:.|..|:..   |...|...||||. ..|| |:|||||||||.
Frog   675 GNIKEGNVSKPEVLQKASVGIIDQKICSVL---YNFSITERMICAGFLDGKVDSCQGDSGGPLAC 736

  Fly   216 --SGGV--LVGVVSWGYGCAYSNYPGVYADVAVLRSWVVST 252
              |.|:  |.|:||||.|||.:..||||:.|..|:.|::.|
Frog   737 EESPGIFFLAGIVSWGIGCAQAKKPGVYSRVTKLKDWILDT 777

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
alphaTry	NP_476771.1	Tryp_SPc	30..249	CDD:214473	88/231 (38%)
tmprss9	XP_002940084.3	SEA	60..156	CDD:396113
		LDLa	186..221	CDD:238060
		Tryp_SPc	234..463	CDD:214473
		Tryp_SPc	547..774	CDD:238113	88/230 (38%)
		LDLa	871..906	CDD:238060
		Tryp_SPc	919..1145	CDD:238113
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910