DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment alphaTry and tmprss3a

DIOPT Version :9

Sequence 1:	NP_476771.1	Gene:	alphaTry / 48316	FlyBaseID:	FBgn0003863	Length:	256	Species:	Drosophila melanogaster
Sequence 2:	XP_021334565.1	Gene:	tmprss3a / 100000148	ZFINID:	ZDB-GENE-070912-70	Length:	543	Species:	Danio rerio

Alignment Length:	258	Identity:	90/258 - (34%)
Similarity:	125/258 - (48%)	Gaps:	20/258 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 LKIVILLSAVVCALGGTVPEGLLPQLDGRIVGGSATTISSFPWQISLQRSGSHSCGGSIYSANII 66
            |.:|..|..:.|        |..|:...|||||:.:....||||:||.....|.|||||.::..|
Zfish   277 LGMVTALKCIAC--------GSRPKFSARIVGGNLSAEGQFPWQVSLHFQNEHLCGGSIITSRWI 333

  Fly    67 VTAAHCLQSVSASVL-QVRAGSTYWSSGGVVA-KVSSFKNHEGYNANTMVNDIAVIRLSSSLSFS 129
            :|||||:..::..:. .|.||.|......|.| .|.....|..|....:.:|||:::|:..|:|:
Zfish   334 LTAAHCVYGIAYPMYWMVYAGLTELPLNAVKAFAVEKIIYHSRYRPKGLDHDIALMKLAQPLTFN 398

  Fly   130 SSIKAISLATYNP--ANGASAAVSGWGTQSSGSSSIPSQLQYVNVNIVSQSQCASSTYGYGSQIR 192
            ..::.|.|..:..  .:|....:||||....|..:..|| ...:|.::|...| |....|...:.
Zfish   399 GMVEPICLPNFGEQFEDGKMCWISGWGATEDGGDASVSQ-HCASVPLISNKAC-SQPEVYQGYLT 461

  Fly   193 NTMICAA--ASGKDACQGDSGGPLV----SGGVLVGVVSWGYGCAYSNYPGVYADVAVLRSWV 249
            ..||||.  ..|.|:|||||||||.    |...|||..|||.|||..|.||||..:....:|:
Zfish   462 AGMICAGYLDGGTDSCQGDSGGPLACEDSSIWKLVGATSWGQGCAEKNKPGVYTRITQSLTWI 524

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
alphaTry	NP_476771.1	Tryp_SPc	30..249	CDD:214473	83/228 (36%)
tmprss3a	XP_021334565.1	LDLa	154..186	CDD:238060
		SRCR_2	191..292	CDD:317845	5/22 (23%)
		Tryp_SPc	298..525	CDD:238113	83/229 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910