Protein Alignment Pkc53E and TPK3

DIOPT Version :10

• Sequence 1: NP_725626.1
• Gene: Pkc53E / 48311
• FlyBaseID: FBgn0003091
• Length: 679
• Species: Drosophila melanogaster
• Sequence 2: NP_012755.1
• Gene: TPK3 / 853688
• SGDID: S000001649
• Length: 398
• Species: Saccharomyces cerevisiae
• Alignment Length: 342
• Identity: 137/342 - (40%)
• Similarity: 208/342 - (60%)
• Gaps: 17/342 - (4%)

  Fly   305 NVPCADDEQDLLKLKQKPSQ-----KKPMVMRSDTNTHTSSKKDMIRATDFNFIKVLGKGSFGKV 364
            |.|...:.::..|||::.|.     ||||:...|    ||.|..:   :||..::.||.||||:|
Yeast    45 NTPVEINGRNSGKLKEEASAGICLVKKPMLQYRD----TSGKYSL---SDFQILRTLGTGSFGRV 102

  Fly   365 LLAERKGSEELYAIKILKKDVIIQDDDVECTMIEKRVLALGEKPPFLVQLHSCFQTMDRLFFVME 429
            .|.....:...||:|.|||..|::...||.|..|:|:|:: ...||::::...||...::|.||:
Yeast   103 HLIRSNHNGRFYALKTLKKHTIVKLKQVEHTNDERRMLSI-VSHPFIIRMWGTFQDSQQVFMVMD 166

  Fly   430 YVNGGDLMFQIQQFGKFKEPVAVFYAAEIAAGLFFLHTKGILYRDLKLDNVLLDADGHVKIADFG 494
            |:.||:|...:::..:|..|||.|||||:...|.:||:|.|:|||||.:|:|||.:||:||.|||
Yeast   167 YIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFG 231

  Fly   495 MCKENIVGDKTTKTFCGTPDYIAPEIILYQPYGKSVDWWAYGVLLYEMLVGQPPFDGEDEEELFA 559
            ..|  .|.| .|.|.||||||||||::..:||.||||||::|||:||||.|..||...:..:.:.
Yeast   232 FAK--YVPD-VTYTLCGTPDYIAPEVVSTKPYNKSVDWWSFGVLIYEMLAGYTPFYNSNTMKTYE 293

  Fly   560 AITDHNVSYPKSLSKEAKEACKGFLTKQPNKRLGCGSSGEEDVRLHPFFRRIDWEKIENREVQPP 624
            .|.:..:.:|.....:|::..|..:|:..::|||...:|.|||:.||:|..:.|||:..|.::.|
Yeast   294 NILNAELKFPPFFHPDAQDLLKKLITRDLSERLGNLQNGSEDVKNHPWFNEVIWEKLLARYIETP 358

  Fly   625 FKPKIKH-RKDVSNFDK 640
            ::|.|:. :.|.|.||:
Yeast   359 YEPPIQQGQGDTSQFDR 375

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pkc53E	NP_725626.1	C1_cPKC_rpt1	44..110	CDD:410383
		C1_cPKC_rpt2	120..173	CDD:410386
		C2_PKC_alpha_gamma	177..307	CDD:175992	1/1 (100%)
		STKc_cPKC	353..672	CDD:270739	121/289 (42%)
TPK3	NP_012755.1	STKc_PKA_like	86..376	CDD:270732	123/294 (42%)