Protein Alignment Pkc53E and PKH3

DIOPT Version :10

• Sequence 1: NP_725626.1
• Gene: Pkc53E / 48311
• FlyBaseID: FBgn0003091
• Length: 679
• Species: Drosophila melanogaster
• Sequence 2: NP_010754.1
• Gene: PKH3 / 852077
• SGDID: S000002874
• Length: 898
• Species: Saccharomyces cerevisiae
• Alignment Length: 312
• Identity: 96/312 - (30%)
• Similarity: 161/312 - (51%)
• Gaps: 42/312 - (13%)

  Fly   338 TSSKKDMIRATDFNFIKVLGKGSFGKVLLA-ERKGSEELYAIKILKKDVIIQDDDVECTMIEKRV 401
            ||.|:.   ..||.|.:.||.||:..|..| ::|...::||||:..|..||::..|:...|||..
Yeast     2 TSRKRS---PHDFIFKEELGHGSYSTVFKALDKKSPNKIYAIKVCSKKHIIKEAKVKYVTIEKNT 63

  Fly   402 L-ALGEK-PPFLVQLHSCFQTMDRLFFVMEYVNGGDLMFQIQQFGKFKEPVAVFYAAEIAAGLFF 464
            : .|.:| ...:::|:..|...:.|:||:::..||:|:..:.:.|.|.:.....:.|::...|.|
Yeast    64 MNLLAQKHHAGIIKLYYTFHDEENLYFVLDFAPGGELLSLLHKMGTFNDIWTRHFTAQLIDALEF 128

  Fly   465 LHTKGILYRDLKLDNVLLDADGHVKIADFGMC---KENIVGD--------------KTTKTFCGT 512
            :|:.||::||||.:|||||.||.:.|.|||..   ..::.||              :...:|.||
Yeast   129 IHSHGIIHRDLKPENVLLDRDGRLMITDFGAAATIDPSLSGDSAKFNSDSNGSKDNQNCASFVGT 193

  Fly   513 PDYIAPEIILYQPYGKSVDWWAYGVLLYEMLVGQPPFDGEDEEELFAAITDHNVSYPKSLSKEAK 577
            .:|::||::||...|...|.||.|.::|:.:.|||||.||:|.:.|..|.  .:.||...:....
Yeast   194 AEYVSPELLLYNQCGYGSDIWALGCMIYQFVQGQPPFRGENELKTFEKIV--ALDYPWGPNNRIN 256

  Fly   578 EA-----------CKGFLTKQPNKRLGCGSSGEEDVRLHPFFRRIDW-EKIE 617
            .:           .:..|..:.|:|:..     |.::.||:|.::|| :||:
Yeast   257 NSTSPINPLVINLVQKILVIEVNERISL-----EQIKRHPYFSKVDWNDKIK 303

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pkc53E	NP_725626.1	C1_cPKC_rpt1	44..110	CDD:410383
		C1_cPKC_rpt2	120..173	CDD:410386
		C2_PKC_alpha_gamma	177..307	CDD:175992
		STKc_cPKC	353..672	CDD:270739	90/297 (30%)
PKH3	NP_010754.1	STKc_PDK1	9..293	CDD:270733	88/290 (30%)