DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pkc53E and AGC1.7

DIOPT Version :9

Sequence 1:	NP_725626.1	Gene:	Pkc53E / 48311	FlyBaseID:	FBgn0003091	Length:	679	Species:	Drosophila melanogaster
Sequence 2:	NP_001185434.1	Gene:	AGC1.7 / 844265	AraportID:	AT1G79250	Length:	555	Species:	Arabidopsis thaliana

Alignment Length:	521	Identity:	128/521 - (24%)
Similarity:	209/521 - (40%)	Gaps:	158/521 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   196 KEGRNLIPMDPNGLS-----DPYVKVKLIP-DDKDQSKKKTRTIKACLNPVWNETLTYDLKPEDK 254
            |:..|||..:|.|.:     :|..|:...| .:..:|:....|                 ||.:
plant    48 KKMDNLIKPEPAGFTNHHRPNPSPKIPSSPGSNMTESQSNLNT-----------------KPNN- 94

  Fly   255 DRRILIEVWDWDRTSRNDFMGALSFGISEIIKNPTNGWFKLLTQDEGEYYNVPCADDEQDLLKLK 319
                       :.::.|..|.:.|..|.....||:
plant    95 -----------NNSNNNSNMSSRSNSIESTSSNPS------------------------------ 118

  Fly   320 QKPSQKKPMV---MRSDTNTHTSSKKDMIRATDFNFIKVLGKGSFGKVLLAERKGSEELYAIKIL 381
                  ||..   :|.|.....:||...:..:||..:|.||.|..|.|.|.|.:|:...:|:|::
plant   119 ------KPHTGGDIRWDAVNTLTSKGVQLGISDFRLLKRLGYGDIGSVYLVELRGTITYFAMKVM 177

  Fly   382 KKDVIIQDDDVECTMIEKRVLALGEKPPFLVQLHSCFQTMDRLF-FVMEYVNGGDL--MFQIQQF 443
            .|..:...:.:.....|:.:|:..:. |||..|:|.|:| |:.: .|||:..||:|  :.|.|..
plant   178 DKASLASRNKLLRAQTEREILSQLDH-PFLPTLYSHFET-DKFYCLVMEFCGGGNLYSLRQKQPN 240

  Fly   444 GKFKEPVAVFYAAEIAAGLFFLHTKGILYRDLKLDNVLLDADGHVKIADFGM------------- 495
            ..|.|..|.|:|:|:...|.:||..||:|||||.:|||:..|||:.::||.:
plant   241 KCFTEDAARFFASEVLLALEYLHMLGIVYRDLKPENVLVRDDGHIMLSDFDLSLRCSVSPTLVKS 305

  Fly   496 ---------------------------C--------------KEN-----------------IVG 502
                                       |              |:|                 ::.
plant   306 SSVHAAGGGSGSSRPVGLIDEDAAVQGCIQPSTFFPRILQSSKKNRKAKSDFGLFVNGSMPELMA 370

  Fly   503 DKT---TKTFCGTPDYIAPEIILYQPYGKSVDWWAYGVLLYEMLVGQPPFDGEDEEELFAAITDH 564
            :.|   :.:|.||.:|:|||||..:.:|.:||||.:|:.:||:|.|..||.|:........:...
plant   371 EPTNVKSMSFVGTHEYLAPEIIRGEGHGSAVDWWTFGIFIYELLYGATPFKGQGNRATLHNVIGQ 435

  Fly   565 NVSYPK--SLSKEAKEACKGFLTKQPNKRLGCGSSGEEDVRLHPFFRRIDWEKIENREVQPPFKP 627
            .:.:|:  .:|..|::..||.|.|:|.||:.. ..|..:::.||||..::|..|  |...||..|
plant   436 ALRFPEVPHVSSAARDLIKGLLVKEPQKRIAY-KRGATEIKQHPFFEGVNWALI--RSATPPHVP 497

  Fly   628 K 628
            :
plant   498 E 498

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pkc53E	NP_725626.1	C1_cPKC_rpt1	44..110	CDD:410383
		C1_cPKC_rpt2	120..173	CDD:410386
		C2_PKC_alpha_gamma	177..307	CDD:175992	19/116 (16%)
		STKc_cPKC	353..672	CDD:270739	101/355 (28%)
AGC1.7	NP_001185434.1	STKc_phototropin_like	144..501	CDD:270726	103/360 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	206	1.000	Inparanoid score	I1276
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.050