Protein Alignment Pkc53E and Rps6kb1

DIOPT Version :10

• Sequence 1: NP_725626.1
• Gene: Pkc53E / 48311
• FlyBaseID: FBgn0003091
• Length: 679
• Species: Drosophila melanogaster
• Sequence 2: XP_063126049.1
• Gene: Rps6kb1 / 83840
• RGDID: 620683
• Length: 546
• Species: Rattus norvegicus
• Alignment Length: 363
• Identity: 144/363 - (39%)
• Similarity: 222/363 - (61%)
• Gaps: 22/363 - (6%)

  Fly   332 SDTNTHTSSKKDMIRATDFNFIKVLGKGSFGKVLLAER---KGSEELYAIKILKKDVIIQD-DDV 392
            |:|:.:...:|  ||...|..::|||||.:|||....:   ..:.:::|:|:|||.:|::: .|.
  Rat    75 SETSVNRGPEK--IRPECFELLRVLGKGGYGKVFQVRKVTGANTGKIFAMKVLKKAMIVRNAKDT 137

  Fly   393 ECTMIEKRVLALGEKPPFLVQLHSCFQTMDRLFFVMEYVNGGDLMFQIQQFGKFKEPVAVFYAAE 457
            ..|..|:.:|. ..|.||:|.|...|||..:|:.::||::||:|..|:::.|.|.|..|.||.||
  Rat   138 AHTKAERNILE-EVKHPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLEREGIFMEDTACFYLAE 201

  Fly   458 IAAGLFFLHTKGILYRDLKLDNVLLDADGHVKIADFGMCKENIVGDKTTKTFCGTPDYIAPEIIL 522
            |:..|..||.|||:|||||.:|::|:..||||:.|||:|||:|.....|.|||||.:|:||||::
  Rat   202 ISMALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDFGLCKESIHDGTVTHTFCGTIEYMAPEILM 266

  Fly   523 YQPYGKSVDWWAYGVLLYEMLVGQPPFDGEDEEELFAAITDHNVSYPKSLSKEAKEACKGFLTKQ 587
            ...:.::||||:.|.|:|:||.|.|||.||:.::....|....::.|..|::||::..|..|.:.
  Rat   267 RSGHNRAVDWWSLGALMYDMLTGAPPFTGENRKKTIDKILKCKLNLPPYLTQEARDLLKKLLKRN 331

  Fly   588 PNKRLGCGSSGEEDVRLHPFFRRIDWEKIENREVQPPFKPKIKHRKDVSNFDKQFTSEKTDLTPT 652
            ...|||.|.....:|:.|||||.|:||::..|:|:|||||.::..:|||.||.:||.:    ||.
  Rat   332 AASRLGAGPGDAGEVQAHPFFRHINWEELLARKVEPPFKPLLQSEEDVSQFDSKFTRQ----TPV 392

  Fly   653 DKVFMMNLDQSE---FVGFSYMNP--------EYVFSP 679
            |......|.:|.   |:||:|:.|        ::.|.|
  Rat   393 DSPDDSTLSESANQVFLGFTYVAPSVLESVKEKFSFEP 430

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pkc53E	NP_725626.1	C1_cPKC_rpt1	44..110	CDD:410383
		C1_cPKC_rpt2	120..173	CDD:410386
		C2_PKC_alpha_gamma	177..307	CDD:175992
		STKc_cPKC	353..672	CDD:270739	135/325 (42%)
Rps6kb1	XP_063126049.1	None