DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pkc53E and KIPK

DIOPT Version :9

Sequence 1:	NP_725626.1	Gene:	Pkc53E / 48311	FlyBaseID:	FBgn0003091	Length:	679	Species:	Drosophila melanogaster
Sequence 2:	NP_001319733.1	Gene:	KIPK / 824455	AraportID:	AT3G52890	Length:	934	Species:	Arabidopsis thaliana

Alignment Length:	591	Identity:	153/591 - (25%)
Similarity:	237/591 - (40%)	Gaps:	164/591 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   128 AGPTFCDHCGSLLYGIYHQGLKCSACDMNVHARCKENVPSLCGCDHTERRGRIYLEINVKENLLT 192
            |....|..|        |..||.::.|.|..:....:.|.:|                 .::|.:
plant   379 ANQLLCQRC--------HCSLKSTSIDDNPPSYTSSHNPKIC-----------------TDSLSS 418

  Fly   193 VQIKEGRNLIPMDPNGLSDPYVKVKLIPDDKDQSKKKTRTIKACLNPVWNETLTYDLKPEDKDRR 257
            |..||..                     ...|::...:..:.                 :..:..
plant   419 VSNKEAH---------------------QGSDENSSGSCNVS-----------------QSSEAD 445

  Fly   258 ILIEVWDWDRTSRNDFMGALSFGISEIIKNPTNG---WFKLLTQDE-GEYYNVPCADDEQDLLKL 318
            |:|...|.. :|.|..:||:   :.:..:|||:.   .|.|.::|. |:|.......:|.:|.:.
plant   446 IVIMKQDVS-SSNNSGIGAM---VEKETENPTSSEKFEFSLSSKDSLGDYSRSTSISEESNLSRF 506

  Fly   319 K--QKPSQKKPMVMRSDTNTHTSSKKDMIRATDFNFIKVLGKGSFGKVLLAERKGSEELYAIKIL 381
            .  .||...  |.:|.:...|...:...:....||.:|.||.|..|.|.|||..|:..|:|||::
plant   507 SCGNKPHMS--MDVRWEAIKHIKVQYGSLGLRHFNLLKKLGCGDIGTVYLAELIGTNCLFAIKVM 569

  Fly   382 KKDVIIQDDDVECTMIEKRVLALGEKPPFLVQLHSCFQTMDRLFFVMEYVNGGDL-MFQIQQFGK 445
            ..:.:.:.........|:.:|.:.:. |||..|::.|.:.:....||||..|||| :.:.:|.|:
plant   570 DNEFLARRKKSPRAQAEREILKMLDH-PFLPTLYAQFTSDNLSCLVMEYCPGGDLHVLRQKQLGR 633

  Fly   446 -FKEPVAVFYAAEIAAGLFFLHTKGILYRDLKLDNVLLDADGHVKIADFGM---CKENIV----- 501
             |.||.|.||.|||...|.:||..||:|||||.:|:|:..|||:.:.||.:   |..|..
plant   634 CFPEPAARFYVAEILLALEYLHMLGIIYRDLKPENILVREDGHIMLTDFDLSLRCAVNPTLVRSN 698

  Fly   502 ---------------------------------------------------GDKTTKT------- 508
                                                               ||..:||
plant   699 SPPGKDPARISGPYNTSNCIQPFCITEPSCQVSCFSPRLSSNQQQGRKPKRGDHLSKTQQHLSRS 763

  Fly   509 ---------------FCGTPDYIAPEIILYQPYGKSVDWWAYGVLLYEMLVGQPPFDGEDEEELF 558
                           |.||.:|:|||||..:.:|.:||||.:||||||:|.|:.||.|.:.:|..
plant   764 LPQLVAEPTEARSNSFVGTHEYLAPEIIKGEGHGAAVDWWTFGVLLYELLYGKTPFKGYNNDETL 828

  Fly   559 AAITDHNVSYPKS--LSKEAKEACKGFLTKQPNKRLGCGSSGEEDVRLHPFFRRIDWEKIENREV 621
            |.:...|:.:|.|  :|.:||:..:|.|.|:|..||| ...|..:::.||||..::|..|  |..
plant   829 ANVVLQNLKFPDSPLVSFQAKDLIRGLLVKEPENRLG-SEKGSVEIKRHPFFEGLNWALI--RCA 890

  Fly   622 QPPFKP 627
            .||..|
plant   891 IPPELP 896

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pkc53E	NP_725626.1	C1_cPKC_rpt1	44..110	CDD:410383
		C1_cPKC_rpt2	120..173	CDD:410386	10/44 (23%)
		C2_PKC_alpha_gamma	177..307	CDD:175992	20/133 (15%)
		STKc_cPKC	353..672	CDD:270739	114/360 (32%)
KIPK	NP_001319733.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	206	1.000	Inparanoid score	I1276
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.050