Protein Alignment Pkc53E and prkchb

DIOPT Version :9

• Sequence 1: NP_725626.1
• Gene: Pkc53E / 48311
• FlyBaseID: FBgn0003091
• Length: 679
• Species: Drosophila melanogaster
• Sequence 2: NP_001038271.1
• Gene: prkchb / 556591
• ZFINID: ZDB-GENE-041001-104
• Length: 676
• Species: Danio rerio
• Alignment Length: 669
• Identity: 278/669 - (41%)
• Similarity: 353/669 - (52%)
• Gaps: 142/669 - (21%)

  Fly    17 EGEAVGENKM-KSRLRKGALKKKNVFNVKDHCFIARFFKQPTFCSHCKDFICGYQSGYAWMGFGK 80
            :.|||...|. |..:||..||::.|..:..|.|:|.|..|||||.|||:||        |...||
Zfish   135 DDEAVNIVKTHKEFVRKKVLKRRKVHQIYGHKFMATFLPQPTFCYHCKNFI--------WGVIGK 191

  Fly    81 QGFQCQVCSYVVHKRCHEYVTFICP--------GKDKGIDSDSPKTQHNFEPFTYAGPTFCDHCG 137
            ||:|||||:.|||||||..|...||        |:.:|...:.|   |.|:...|..||:|:|||
Zfish   192 QGYQCQVCTCVVHKRCHALVVTECPRMRKDANEGQRQGFSINLP---HQFKEHNYKVPTYCNHCG 253

  Fly   138 SLLYGIYHQGLKCSACDMNVHARCKENVPSLCGCDHTERRGRIYLEINVKENLLTVQIKEGRNLI 202
            |||||:..|||.|..|.||:|.||::||...||.|:.|...:: .||.:   |.|:..::.:..:
Zfish   254 SLLYGLVKQGLHCKICKMNIHKRCEQNVAPNCGVDNAELASKL-SEIGL---LNTISKRKSQGSL 314

  Fly   203 PMDPNGLSDPYVKVKLIPDDKDQSKKKTRTIKACLNPVWNETLTYDLKPEDKDRRILIEVWDWDR 267
            .|...........::...::.|:     ..:|.||.
Zfish   315 HMSSVRSQSSTTSIETTEEESDE-----EAVKVCLE----------------------------- 345

  Fly   268 TSRNDFMGALSFGISEIIKNPTNGWFKLLTQDEGEYYNVPCADDEQDLLKLKQKPSQKKPMVMRS 332
                                                                             
Zfish   346 ----------------------------------------------------------------- 345

  Fly   333 DTNTHTSSKKDMIRATDFNFIKVLGKGSFGKVLLAERKGSEELYAIKILKKDVIIQDDDVECTMI 397
                            ||:|::||||||||||:||..|....::|:|:||||||:|:||||.||.
Zfish   346 ----------------DFSFLQVLGKGSFGKVMLARLKSDHRVFAVKMLKKDVILQEDDVEATMT 394

  Fly   398 EKRVLALGEKPPFLVQLHSCFQTMDRLFFVMEYVNGGDLMFQIQQFGKFKEPVAVFYAAEIAAGL 462
            |||||.|..:.|||.||:.||||.:|||||||:||||||||.||:..:|.||.|.|||||:.:.|
Zfish   395 EKRVLTLAHQHPFLTQLYYCFQTTERLFFVMEFVNGGDLMFHIQKCRRFDEPRAQFYAAEVTSAL 459

  Fly   463 FFLHTKGILYRDLKLDNVLLDADGHVKIADFGMCKENIVGDKTTKTFCGTPDYIAPEIILYQPYG 527
            .|||:|||:||||||||:|||.|||.|:||||||||.|...|.|.|||||||||||||:..:.||
Zfish   460 KFLHSKGIIYRDLKLDNILLDRDGHCKLADFGMCKEEIFNGKLTSTFCGTPDYIAPEILQEELYG 524

  Fly   528 KSVDWWAYGVLLYEMLVGQPPFDGEDEEELFAAITDHNVSYPKSLSKEAKEACKGFLTKQPNKRL 592
            .||||||.||||||||.|..||:.|.|:|||..|....:.|...||.||::..||.||:.|..||
Zfish   525 VSVDWWALGVLLYEMLSGHAPFEAETEDELFECILKDEIIYSSWLSYEAEDILKGLLTRDPACRL 589

  Fly   593 GC--GSSGEEDVRLHPFFRRIDWEKIENREVQPPFKPKIKHRKDVSNFDKQFTSEKTDLTPTDKV 655
            ||  ...|||.:..|.||..:||||:..||:.|||.|:|...:||:|||..||.|...|||.::
Zfish   590 GCIDNDGGEEAITAHAFFTGLDWEKLYRREITPPFTPRINSIEDVNNFDPDFTQEDPCLTPIEE- 653

  Fly   656 FMMNLDQSEFVGFSYMNPE 674
            .:....|..|..|||:.||
Zfish   654 SLFPFHQDGFKDFSYIAPE 672

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pkc53E	NP_725626.1	C1_cPKC_rpt1	44..110	CDD:410383	35/73 (48%)
		C1_cPKC_rpt2	120..173	CDD:410386	28/52 (54%)
		C2_PKC_alpha_gamma	177..307	CDD:175992	9/129 (7%)
		STKc_cPKC	353..672	CDD:270739	187/320 (58%)
prkchb	NP_001038271.1	C2_PKC_epsilon	3..133	CDD:175981
		C1_1	165..216	CDD:278556	32/58 (55%)
		C1_1	236..288	CDD:278556	28/51 (55%)
		S_TKc	347..607	CDD:214567	160/259 (62%)
		PKc_like	351..673	CDD:304357	189/323 (59%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170583316
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG51944
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000117
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X125
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.850