Protein Alignment Pkc53E and aurkb

DIOPT Version :10

• Sequence 1: NP_725626.1
• Gene: Pkc53E / 48311
• FlyBaseID: FBgn0003091
• Length: 679
• Species: Drosophila melanogaster
• Sequence 2: XP_012809281.1
• Gene: aurkb / 549613
• XenbaseID: XB-GENE-1019626
• Length: 370
• Species: Xenopus tropicalis
• Alignment Length: 276
• Identity: 86/276 - (31%)
• Similarity: 145/276 - (52%)
• Gaps: 14/276 - (5%)

  Fly   349 DFNFIKVLGKGSFGKVLLAERKGSEELYAIKILKKDVIIQDDDVECTMIEKRVLALGEKPPFLVQ 413
            ||:..:.||||.||.|.||..|.::.:.|:|:|.|.. ::.:.||..:..:..:....:.|.:::
 Frog   102 DFDIGRPLGKGKFGNVYLARDKQNKFIMALKVLFKSQ-LEKEGVEHQLRREIEIQSHLRHPNILR 165

  Fly   414 LHSCFQTMDRLFFVMEYVNGGDLMFQIQQFGKFKEPVAVFYAAEIAAGLFFLHTKGILYRDLKLD 478
            :::.|....|::.::|:...|:|..::|:.|:|.|..:..:..|:|..|.:.|.:.:::||:|.:
 Frog   166 MYNYFHDRKRIYLMLEFAPRGELYKELQKHGRFDEQRSATFMEELADALQYCHERKVIHRDIKPE 230

  Fly   479 NVLLDADGHVKIADFGMCKENIVGDKTTKTFCGTPDYIAPEIILYQPYGKSVDWWAYGVLLYEML 543
            |:|:...|.:||||||....  ......:|.|||.||:.||:|..:.:.:.||.|..|||.:|.|
 Frog   231 NLLMGYKGELKIADFGWSVH--APSLRRRTMCGTLDYLPPEMIEGKTHDEKVDLWCAGVLCFEFL 293

  Fly   544 VGQPPFDGEDEEELFAAITDHNVSYPKSLSKEAKEACKGFLTKQPNKRLGCGSSGEEDVRLHPFF 608
            ||.||||.....|....|.:.::.:|..||..:|:.....|...|.:||..     :.|..||
 Frog   294 VGMPPFDSPSHTETHRRIVNVDLKFPPFLSDGSKDLISKLLRYHPPQRLPL-----KGVMEHP-- 351

  Fly   609 RRIDWEKIENREVQPP 624
                |.|..:|.|.||
 Frog   352 ----WVKANSRRVLPP 363

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pkc53E	NP_725626.1	C1_cPKC_rpt1	44..110	CDD:410383
		C1_cPKC_rpt2	120..173	CDD:410386
		C2_PKC_alpha_gamma	177..307	CDD:175992
		STKc_cPKC	353..672	CDD:270739	84/272 (31%)
aurkb	XP_012809281.1	STKc_Aurora-B_like	96..365	CDD:271019	86/276 (31%)