Protein Alignment Pkc53E and prkcaa

DIOPT Version :10

• Sequence 1: NP_725626.1
• Gene: Pkc53E / 48311
• FlyBaseID: FBgn0003091
• Length: 679
• Species: Drosophila melanogaster
• Sequence 2: XP_021332537.1
• Gene: prkcaa / 497384
• ZFINID: ZDB-GENE-050208-100
• Length: 679
• Species: Danio rerio
• Alignment Length: 662
• Identity: 443/662 - (66%)
• Similarity: 533/662 - (80%)
• Gaps: 26/662 - (3%)

  Fly    31 RKGALKKKNVFNVKDHCFIARFFKQPTFCSHCKDFICGYQSGYAWMGFGKQGFQCQVCSYVVHKR 95
            |||||::|||..||:|.|.|||||||||||||.|||        | ||||||||||||.:|||||
Zfish    20 RKGALRQKNVHEVKNHKFTARFFKQPTFCSHCTDFI--------W-GFGKQGFQCQVCCFVVHKR 75

  Fly    96 CHEYVTFICPGKDKGIDSDSPKTQHNFEPFTYAGPTFCDHCGSLLYGIYHQGLKCSACDMNVHAR 160
            |||.|||.|||.|||.|:|.|:::|.|:..||..|||||||||||||:.|||:||.:||||||.:
Zfish    76 CHELVTFSCPGADKGPDTDDPRSKHKFKIHTYGSPTFCDHCGSLLYGLIHQGMKCDSCDMNVHKQ 140

  Fly   161 CKENVPSLCGCDHTERRGRIYLEINVKENLLTVQIKEGRNLIPMDPNGLSDPYVKVKLIPDDKDQ 225
            |..|||||||.||||||||:|::|.|..:.:.|.:.||:||||||||||||||||:|||||.|::
Zfish   141 CVMNVPSLCGTDHTERRGRLYMKIEVIGDKMHVTVGEGKNLIPMDPNGLSDPYVKLKLIPDPKNE 205

  Fly   226 SKKKTRTIKACLNPVWNETLTYDLKPEDKDRRILIEVWDWDRTSRNDFMGALSFGISEIIKNPTN 290
            :|:||:||::.|||.||||.|:.|||.|||||:.:||||||||:||||||::|||:||::|:|..
Zfish   206 TKQKTKTIRSSLNPTWNETFTFKLKPADKDRRLAVEVWDWDRTTRNDFMGSMSFGVSELMKSPVC 270

  Fly   291 GWFKLLTQDEGEYYNVPCADDEQDLLKLKQK----------------PSQKKPMVMRSDTNTHTS 339
            ||:|:|.|:||||||||..|::....:|:||                |.:|....:....::.||
Zfish   271 GWYKMLNQEEGEYYNVPIPDEDDPDTELRQKFEDETLEDLEQIAKLGPPKKNITALDDSGSSITS 335

  Fly   340 SKKDMIRATDFNFIKVLGKGSFGKVLLAERKGSEELYAIKILKKDVIIQDDDVECTMIEKRVLAL 404
            |..|.:|.:||||:.||||||||||:|||.|.|:||:|||||||||:||||||||||:||||||.
Zfish   336 SNVDNVRLSDFNFLAVLGKGSFGKVMLAEMKSSDELFAIKILKKDVVIQDDDVECTMVEKRVLAQ 400

  Fly   405 GEKPPFLVQLHSCFQTMDRLFFVMEYVNGGDLMFQIQQFGKFKEPVAVFYAAEIAAGLFFLHTKG 469
            .:|||||.||||||||:|||:||||||||||||:.|||.||||||.|||||||||.||||||.||
Zfish   401 QDKPPFLTQLHSCFQTVDRLYFVMEYVNGGDLMYHIQQVGKFKEPQAVFYAAEIAVGLFFLHKKG 465

  Fly   470 ILYRDLKLDNVLLDADGHVKIADFGMCKENIVGDKTTKTFCGTPDYIAPEIILYQPYGKSVDWWA 534
            |:|||||||||:|||:||:|||||||||||||...||:||||||||||||||.|||||:||||||
Zfish   466 IIYRDLKLDNVMLDAEGHIKIADFGMCKENIVEGVTTRTFCGTPDYIAPEIIAYQPYGRSVDWWA 530

  Fly   535 YGVLLYEMLVGQPPFDGEDEEELFAAITDHNVSYPKSLSKEAKEACKGFLTKQPNKRLGCGSSGE 599
            |||||||||.||||||||||:|||.:|.:|||||.|:|||||...|||.:||.|:||||||..||
Zfish   531 YGVLLYEMLAGQPPFDGEDEDELFQSIMEHNVSYSKTLSKEAVSICKGLMTKHPSKRLGCGQEGE 595

  Fly   600 EDVRLHPFFRRIDWEKIENREVQPPFKPKIKHRKDVSNFDKQFTSEKTDLTPTDKVFMMNLDQSE 664
            .|:|.|.|||||||:::.|||||||||||: ..|...||||.||..:..|||.|::.:.|:||::
Zfish   596 RDIREHAFFRRIDWDRLANREVQPPFKPKV-CGKGAENFDKFFTRTQPQLTPPDELVIANIDQAD 659

  Fly   665 FVGFSYMNPEYV 676
            |.||:::||::|
Zfish   660 FDGFTFVNPQFV 671

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pkc53E	NP_725626.1	C1_cPKC_rpt1	44..110	CDD:410383	47/65 (72%)
		C1_cPKC_rpt2	120..173	CDD:410386	36/52 (69%)
		C2_PKC_alpha_gamma	177..307	CDD:175992	84/129 (65%)
		STKc_cPKC	353..672	CDD:270739	237/318 (75%)
prkcaa	XP_021332537.1	C1_cPKC_rpt1	33..90	CDD:410383	47/65 (72%)
		C1_cPKC_rpt2	100..153	CDD:410386	36/52 (69%)
		C2_PKC_alpha_gamma	157..287	CDD:175992	84/129 (65%)
		STKc_cPKC_alpha	335..675	CDD:270766	248/338 (73%)