Protein Alignment Pkc53E and gwl

DIOPT Version :9

• Sequence 1: NP_725626.1
• Gene: Pkc53E / 48311
• FlyBaseID: FBgn0003091
• Length: 679
• Species: Drosophila melanogaster
• Sequence 2: NP_524860.2
• Gene: gwl / 45969
• FlyBaseID: FBgn0260399
• Length: 846
• Species: Drosophila melanogaster
• Alignment Length: 821
• Identity: 130/821 - (15%)
• Similarity: 190/821 - (23%)
• Gaps: 509/821 - (61%)

  Fly   310 DDEQDLLKLKQKPSQKKPMVMRSDTNTHTSSKKDMIRATDFNFIKVLGKGSFGKVLLA-ERKGSE 373
            |.||.|.|:.         ::.:....|:.:.| :....||..||.:.:|:||||.|. :...|:
  Fly    27 DSEQLLDKIN---------ILTTKPENHSQNAK-LPTIKDFVIIKPISRGAFGKVFLGYKNNDSK 81

  Fly   374 ELYAIKILKKDVIIQDDDVECTMIEKRVLALGEKPPFLVQLHSCFQTMDRLFFVMEYVNGGDLMF 438
            .|:|||:::|..:|..:.|...:.|:..||| .:..|.|.|....|::..::.||||:.||||..
  Fly    82 RLFAIKVMRKSEMINKNMVSQVITERNALAL-SRSQFCVSLFYSLQSLSYVYLVMEYMVGGDLKS 145

  Fly   439 QIQQFGKFKEPVAVFYAAEIAAGLFFLHTKGILYRDLKLDNVLLDADGHVKIADFGM-------- 495
            .:..||.|.||.|.||.||:...|.:||..||::||:|.||:||.:.||||:.|||:
  Fly   146 LLAMFGYFDEPTARFYVAEMVMALQYLHQHGIVHRDIKPDNMLLSSSGHVKLTDFGLSKIDMRRD 210

  Fly   496 ----------------------------------------------------------------- 495
                                                                             
  Fly   211 LEISDLINCSPNLNARTPGQLLSLTSHLSFGSEKKLNDFGSVSSGQNNGMGSVATGTSHLLQAIN 275

  Fly   496 -----------------------------------------------CKENI------------- 500
                                                           |..|:
  Fly   276 KHSLIMELSDSEGDTSLNDAEKTSDSKISGVSPFFSAEEANESITHTCTTNVNPQDSSSSCSFHT 340

  Fly   501 ----------------------------------------------------------------- 500
                                                                             
  Fly   341 CNSADLSKCSPPLESKDGAAAGNAIPSKRRVEFVLDAAPCQGCKLAEQDSSNMATNDGKHLPKID 405

  Fly   501 ----------------------------------------------------------------- 500
                                                                             
  Fly   406 NAIEASFEFSMVRRRSVDERNRISKGPEDSGVSSRKGDDYSSCHLNLNSESTASSIEKNVDNLSQ 470

  Fly   501 ----------------------------------------------------------------- 500
                                                                             
  Fly   471 SKEDFSCSDYSRSYNVTNGNEMSGINMNSPFRNLSKHFKRPDFLRGMKRKINLVNRSDNMSSMDT 535

  Fly   501 ----------------------VGDKTTK------------------------------------ 507
                                  :|..|.|
  Fly   536 DGCSSSNGSTNTGLTQEIEILNIGSSTPKKRKARSSPIRGVLKVRSLSDDEMPINHLLGPEANVA 600

  Fly   508 ----------------------------------------------------------------- 507
                                                                             
  Fly   601 NVVFSTPVSSQKLPRRDGGLLGKLKATRFALPLSIENKKREHATADKMSGIQYHLKLSDDPTMSP 665

  Fly   508 ------------------------------------TFCGTPDYIAPEIILYQPYGKSVDWWAYG 536
                                                ...|||||:|||::|.|.:|.:|||||.|
  Fly   666 INHGAGNLPKTPKNVNINTPFRTPKSVRRGARVSNERILGTPDYLAPELLLKQGHGPAVDWWALG 730

  Fly   537 VLLYEMLVGQPPFDGEDEEELFAAITDHNVSYP---KSLSKEAKEACKGFLTKQPNKRLGCGSSG 598
            |..||.:.|.|||:.|..:::|..|.:.|:.:|   ::||.|:.||.:..||..||:|     ..
  Fly   731 VCFYEFMTGIPPFNDETPQKVFDNILNKNIEWPEGDEALSVESMEAVELLLTMDPNER-----PA 790

  Fly   599 EEDVRLHPFFRRIDWEKIENREVQPPFKPKIKHRKDVSNFD 639
            .::|:....|..||||.|.|.|  |||.|...:..|...||
  Fly   791 AKEVQQMRHFACIDWENIGNTE--PPFVPTPDNPTDTGYFD 829

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pkc53E	NP_725626.1	C1_cPKC_rpt1	44..110	CDD:410383
		C1_cPKC_rpt2	120..173	CDD:410386
		C2_PKC_alpha_gamma	177..307	CDD:175992
		STKc_cPKC	353..672	CDD:270739	121/778 (16%)
gwl	NP_524860.2	STKc_MASTL	52..>255	CDD:270761	63/203 (31%)
		S_TKc	57..>205	CDD:214567	62/148 (42%)
		PKc_like	<655..835	CDD:304357	55/182 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24356
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100