DRSC/TRiP Functional Genomics Resources

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Protein Alignment Pkc53E and wts

DIOPT Version :9

Sequence 1:NP_725626.1 Gene:Pkc53E / 48311 FlyBaseID:FBgn0003091 Length:679 Species:Drosophila melanogaster
Sequence 2:NP_733403.1 Gene:wts / 43651 FlyBaseID:FBgn0011739 Length:1105 Species:Drosophila melanogaster


Alignment Length:519 Identity:151/519 - (29%)
Similarity:244/519 - (47%) Gaps:120/519 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly   219 IPDDKDQSKKKTRTIKACLNPVWNETLTYDLKPEDKDRRILIEVWDWDRTSRNDFMGALSFGISE 283
            ||:.|..||:|                    :.|.|:.||       .:.|...|...:...|..
  Fly   626 IPERKKISKEK--------------------EEERKEFRI-------RQYSPQAFKFFMEQHIEN 663

  Fly   284 IIKNPTNGWFKLLTQDEGEYYNVPCADDEQDLLKLKQKPSQKKPMVMRSDTNTHTSSKKDMIRAT 348
            :||:.....:: ..|.|.|.:.|...|..|  :::::..:||:...:|        .|:..:..:
  Fly   664 VIKSYRQRTYR-KNQLEKEMHKVGLPDQTQ--IEMRKMLNQKESNYIR--------LKRAKMDKS 717

  Fly   349 DFNFIKVLGKGSFGKVLLAER-KGSEELYAIKILKKDVIIQDDDVECTMIEKRVLALGEKPPFLV 412
            .|..:|.:|.|:||:|.|..: ..|..|||:|.|:|..:::.:.|.....|:.:||..:. .::|
  Fly   718 MFVKLKPIGVGAFGEVTLVSKIDTSNHLYAMKTLRKADVLKRNQVAHVKAERDILAEADN-NWVV 781

  Fly   413 QLHSCFQTMDRLFFVMEYVNGGDLMFQIQQFGKFKEPVAVFYAAEIAAGLFFLHTKGILYRDLKL 477
            :|:..||..|.|:|||:|:.|||||..:.:.|.|:|.:|.||.||:...:..:|..|.::||:|.
  Fly   782 KLYYSFQDKDNLYFVMDYIPGGDLMSLLIKLGIFEEELARFYIAEVTCAVDSVHKMGFIHRDIKP 846

  Fly   478 DNVLLDADGHVKIADFGMC------------------------------KENIVGDKTT------ 506
            ||:|:|.|||:|:.|||:|                              .||  |.|.|      
  Fly   847 DNILIDRDGHIKLTDFGLCTGFRWTHNSKYYQENGNHSRQDSMEPWEEYSEN--GPKPTVLERRR 909

  Fly   507 ---------KTFCGTPDYIAPEIILYQPYGKSVDWWAYGVLLYEMLVGQPPFDGEDEEELFAAIT 562
                     .:..|||:|||||::....|.:..|:|:.||:|||||||||||......|....: 
  Fly   910 MRDHQRVLAHSLVGTPNYIAPEVLERSGYTQLCDYWSVGVILYEMLVGQPPFLANSPLETQQKV- 973

  Fly   563 DHNVSYPKS--------LSKEAKEACKGFLTKQPNKRLGCGSSGEEDVRLHPFFRRIDWEKIENR 619
               :::.|:        ||:||.:..:. |....:||||   ...::|:.|.||:.||:  .:.|
  Fly   974 ---INWEKTLHIPPQAELSREATDLIRR-LCASADKRLG---KSVDEVKSHDFFKGIDF--ADMR 1029

  Fly   620 EVQPPFKPKIKHRKDVSNFD----KQFTSEKTDLTPTDKVFMMNLDQSE--FVGFSYMNPEYVF 677
            :.:.|:.|:|||..|.||||    ::..|..:.::..|.|     ||::  |.||.    |:.|
  Fly  1030 KQKAPYIPEIKHPTDTSNFDPVDPEKLRSNDSTMSSGDDV-----DQNDRTFHGFF----EFTF 1084

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Pkc53ENP_725626.1 C1_cPKC_rpt1 44..110 CDD:410383
C1_cPKC_rpt2 120..173 CDD:410386
C2_PKC_alpha_gamma 177..307 CDD:175992 18/87 (21%)
STKc_cPKC 353..672 CDD:270739 123/378 (33%)
wtsNP_733403.1 STKc_LATS 717..1078 CDD:270749 122/378 (32%)
S_TKc 719..1020 CDD:214567 101/311 (32%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - P PTHR24356
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
22.010

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