Protein Alignment Pkc53E and PKD

DIOPT Version :10

• Sequence 1: NP_725626.1
• Gene: Pkc53E / 48311
• FlyBaseID: FBgn0003091
• Length: 679
• Species: Drosophila melanogaster
• Sequence 2: NP_001262705.1
• Gene: PKD / 42203
• FlyBaseID: FBgn0038603
• Length: 906
• Species: Drosophila melanogaster
• Alignment Length: 781
• Identity: 174/781 - (22%)
• Similarity: 281/781 - (35%)
• Gaps: 235/781 - (30%)

  Fly    43 VKDHCFIARFFKQPTFCSHCKDFICGYQSGYAWMGFGKQGFQCQVCSYVVHKRCHEYVTFIC--- 104
            :|.|......:|.||||..|.:.:         .|..:||.:|..|....||||...:...|
  Fly   102 LKPHSLNVHSYKGPTFCDFCGEML---------FGLVRQGLKCDGCGQNYHKRCVVKIPNNCNRS 157

  Fly   105 -------------------------------------------PGKDKGIDSDSPKT-------Q 119
                                                       ||:.:...|...:.       .
  Fly   158 NDATSRRSFTLQAPRSPSGSSQQSLVSTEDSTGRNDSSSSLNIPGRHQRTHSSGSRNGLMVLRIP 222

  Fly   120 HNFEPFTYAGPTFCDHCGSLLYGIYHQGLKCSACDMNVHARCKENVPSLCGCDHTERRGRIYLEI 184
            |.|...||..||.|..|..||.|::.|||:|..|..|.|.:|.:.||.  .|....:..::.::.
  Fly   223 HTFMVHTYGIPTVCQLCKKLLKGLFKQGLQCRDCQYNTHKKCMDKVPH--DCTGEAQLSQLQIQA 285

  Fly   185 NVKE--NLLTVQ------------------IKEGRNLI---PMD-PNGLSDPY------VKVKLI 219
            ..||  |....:                  :..|.||:   |.: |..|::.:      |...|:
  Fly   286 GAKERDNFFREEFDDSDGDDGSEYGKYKSAMSSGVNLVAGRPREAPKALTNAHNSPPELVNGGLV 350

  Fly   220 PD---------------DKDQSKKKTRTIKACLNPVWNETLTYDLK-PEDKDRRILIEVWDWDRT 268
            .|               ..:||:..|.:..:...|:..  :...:| .:.:..:.|.|.|....|
  Fly   351 DDSSVSGGETSKSSSDGQSEQSQSSTSSSPSANIPLMR--IVQSVKHTKKRGGQALKEGWLVHYT 413

  Fly   269 SRNDFMGALSFGISEIIKNPTNGWFKLLTQDEGEYYN--VPCADDEQDLLKLK------------ 319
            |       |...:........:....|...::|..|:  :|.|    :||.::
  Fly   414 S-------LDKAVKRYYWRLDSKTITLFVSEQGSKYHKELPLA----ELLSIESHLGDPRPECNY 467

  Fly   320 --------------QKP--SQKKPMVMR---------SD----------------TNTHTSSKKD 343
                          |.|  ..|:...:|         ||                |||.....::
  Fly   468 CFELRLPNLSYFVGQDPQVGAKEEQAVRLPPPDSGIGSDIAKSWETSIRQAFMHVTNTQCCESEE 532

  Fly   344 MIRATDFNFI------KVLGKGSFGKVLLAERKGSEELYAIKI-------------LKKDVIIQD 389
            .::  |...:      :|||.|.||.|.....|.::...|||:             ||.:|.|..
  Fly   533 QVQ--DMGQLYQIFPDEVLGSGQFGVVYGGVHKKTQREVAIKVIDKLRFPTKQEAQLKNEVAILQ 595

  Fly   390 DDVECTMIEKRVLALGEKPPFLVQLHSCFQTMDRLFFVMEYVNGGDLMFQIQQF--GKFKEPVAV 452
            :...|.               :|.|...|:|.:|:|.|||.:. ||::..|...  |:..|.|..
  Fly   596 NISHCG---------------VVNLERMFETPERIFVVMEKLK-GDMLEMILSHARGRLSERVTK 644

  Fly   453 FYAAEIAAGLFFLHTKGILYRDLKLDNVLLDADG---HVKIADFGMCKENIVGDKT-TKTFCGTP 513
            |...:|...|.:||::.|::.|||.:||||.:|.   .||:.|||..:  |:|:|: .::..|||
  Fly   645 FLITQILIALKYLHSQNIVHCDLKPENVLLSSDAEFPQVKLCDFGYAR--IIGEKSFRRSVVGTP 707

  Fly   514 DYIAPEIILYQPYGKSVDWWAYGVLLYEMLVGQPPFDGEDEEELFAAITDHNVSYP----KSLSK 574
            .|:|||::..:.|.:|:|.|:.||::|..|.|..||:  :||::...|.:....||    |.:|.
  Fly   708 AYLAPEVLRNKGYNRSLDMWSVGVIIYVSLSGTFPFN--EEEDINDQIQNAAFMYPPNPWKEISS 770

  Fly   575 EAKEACKGFLTKQPNKRLGCGSSGEEDVRLHPFFR-RIDWEKIENREVQPPFKPKIKHRKDVSNF 638
            .|.:.....|..:..||.....|     .||.:.: :..:..:.|.|.|......:.|..|...:
  Fly   771 NAIDLINNLLQVKQRKRYTVDKS-----LLHYWLQDKQTYRDLRNLEAQVGAGRYLTHEADDLRW 830

  Fly   639 D 639
            |
  Fly   831 D 831

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pkc53E	NP_725626.1	C1_cPKC_rpt1	44..110	CDD:410383	20/111 (18%)
		C1_cPKC_rpt2	120..173	CDD:410386	22/52 (42%)
		C2_PKC_alpha_gamma	177..307	CDD:175992	26/177 (15%)
		STKc_cPKC	353..672	CDD:270739	91/317 (29%)
PKD	NP_001262705.1	C1_PKD_rpt1	102..157	CDD:410345	18/63 (29%)
		C1_PKD_rpt2	222..275	CDD:410346	22/54 (41%)
		PH_PKD	396..522	CDD:269945	19/136 (14%)
		STKc_PKD	539..798	CDD:270984	85/283 (30%)