Protein Alignment Pkc53E and JIL-1

DIOPT Version :10

• Sequence 1: NP_725626.1
• Gene: Pkc53E / 48311
• FlyBaseID: FBgn0003091
• Length: 679
• Species: Drosophila melanogaster
• Sequence 2: NP_648432.1
• Gene: JIL-1 / 39241
• FlyBaseID: FBgn0020412
• Length: 1207
• Species: Drosophila melanogaster
• Alignment Length: 585
• Identity: 157/585 - (26%)
• Similarity: 258/585 - (44%)
• Gaps: 120/585 - (20%)

  Fly   196 KEGRNLIPMDPNGLSDPYVKVKLIPDDKDQSKKK------TRTIKACLNPVWN-----ETLTYDL 249
            :|..:|...:|:.:...::..:|:.:...:::|.      |...|:.||...:     :||.|:.
  Fly    27 RESESLAYEEPDQMVRNHLNGQLVANGNGKTRKNSNSETMTNGKKSKLNTEGSGSGSGKTLNYNN 91

  Fly   250 KPEDKDRRILIEVWDWDRTSRNDFMGALSFGISEIIKNPT---------------------NGWF 293
            ...:.:..........:.:|:.....|..:...|.|..||                     :|
  Fly    92 NNNNNNSISATNGQYTNSSSKTTSASARDYTYRETISPPTPPSPPTTNVADIVCISDAESEDG-- 154

  Fly   294 KLLTQDEGEYYNVPCADDEQDLLKLKQK-----------------------------------PS 323
               ...|.|||:....:||.:.:::.:.                                   ||
  Fly   155 ---RDPEREYYDQDMEEDEPNGIEIDESSSSLSKAKSNNAAAAAAAAAAAAAAAASKASSSTTPS 216

  Fly   324 QKKP----MVMRSDTNTH-------TSSK-------KDMIRATDFNFIKVLGKGSFGKVLLAE-- 368
            ...|    ..:..|...|       |..|       .:.:...||..|:|||.|::|:|.|..
  Fly   217 YAMPTSNSTPLDLDNEAHQRDLEAVTDLKYYVKLYSDEAVSLNDFKIIRVLGTGAYGRVFLVRKL 281

  Fly   369 -RKGSEELYAIKILKKDVIIQD-DDVECTMIEKRVLALGEKPPFLVQLHSCFQTMDRLFFVMEYV 431
             |..:.:|||:|:|.|..::|. ...|.|..|:.||...::.||||.||..||:..:|:.|:::.
  Fly   282 TRHDAGKLYAMKVLNKITVVQKRKTAEHTKTERVVLEAIQRNPFLVSLHYAFQSSSKLYLVLDFA 346

  Fly   432 NGGDLMFQIQQFGKFKEPVAVFYAAEIAAGLFFLHTKGILYRDLKLDNVLLDADGHVKIADFGMC 496
            |||:|...:.....|:|.....|.||:...|..||..||:|||:||:|:|||.:||:.::|||:.
  Fly   347 NGGELFTHLYHSENFEESRVRVYIAEVVLALEQLHQLGIIYRDIKLENILLDGEGHIVLSDFGLS 411

  Fly   497 K----ENIVGDKTTKTFCGTPDYIAPEIILYQPYG--KSVDWWAYGVLLYEMLVGQPPF---DGE 552
            |    ||   :....:||||.:|:|||||...|.|  .:||||:.|||.:|:|.|..||   ||:
  Fly   412 KILTAEN---EYRAHSFCGTLEYMAPEIIRTGPPGHDSAVDWWSVGVLTFELLTGASPFATSDGQ 473

  Fly   553 -DEEELFAAITDHNVSYPKSLSKEAKEACKGFLTKQPNKRLGCGSSGEEDVRLHPFFRRIDWEKI 616
             .:.|:...|.......|.|.|..|::.....|.|.|.:|||.......:::.||||..|:|:::
  Fly   474 VQQSEISRRIQKEQPMIPSSFSANARDFVLKMLEKNPKRRLGGNHRDASEIKEHPFFNGINWQEL 538

  Fly   617 ENREVQPPFKPKIKHRKDVSNFDKQFTSE-----KTDLTPTDKVFMMNLDQSEFVGFSYMNPEYV 676
            ..:..:.|:||.:....||.||..:||.:     :.|..|:    .:.|    |.|::|:.||::
  Fly   539 RTKRRKAPYKPTLTAEDDVQNFSNEFTDQVPEDPECDAPPS----RIRL----FRGYTYVAPEHL 595

  Fly   677  676
              Fly   596  595

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pkc53E	NP_725626.1	C1_cPKC_rpt1	44..110	CDD:410383
		C1_cPKC_rpt2	120..173	CDD:410386
		C2_PKC_alpha_gamma	177..307	CDD:175992	23/142 (16%)
		STKc_cPKC	353..672	CDD:270739	121/337 (36%)
JIL-1	NP_648432.1	STKc_MSK_N	266..533	CDD:270735	103/269 (38%)
		S_TK_X	532..591	CDD:214529	17/66 (26%)
		S_TKc	632..886	CDD:214567