Protein Alignment Pkc53E and prkcda

DIOPT Version :9

• Sequence 1: NP_725626.1
• Gene: Pkc53E / 48311
• FlyBaseID: FBgn0003091
• Length: 679
• Species: Drosophila melanogaster
• Sequence 2: NP_999873.1
• Gene: prkcda / 334571
• ZFINID: ZDB-GENE-030131-6503
• Length: 684
• Species: Danio rerio
• Alignment Length: 656
• Identity: 274/656 - (41%)
• Similarity: 358/656 - (54%)
• Gaps: 135/656 - (20%)

  Fly    31 RKGALKKKNVFNVKDHCFIARFFKQPTFCSHCKDFICGYQSGYAWMGFGKQGFQCQVCSYVVHKR 95
            |:||:|:..:..:|:|.|||.||:||||||.|:||:        | |..|||::|:.|:..:||:
Zfish   145 RRGAIKQAKIHFIKNHEFIATFFRQPTFCSVCRDFV--------W-GLNKQGYKCRQCNAAIHKK 200

  Fly    96 CHEYVTFICPG-----KDKGIDSDSPKTQ--HNFEPFTYAGPTFCDHCGSLLYGIYHQGLKCSAC 153
            |.:.:...|.|     :|.....:..|..  |.|:...|..|||||||||||:|:..|||||..|
Zfish   201 CIDKIIGRCTGTAANSRDTMFQKERFKIDMPHRFKTNNYMSPTFCDHCGSLLWGLVKQGLKCEDC 265

  Fly   154 DMNVHARCKENVPSLCGCDHTERRGRIYLEINVKENLLTVQIKEGRNLIPMDPNGLSDPYVKVKL 218
            .||||.:|:..|.:|||                                           :..||
Zfish   266 SMNVHHKCQTKVANLCG-------------------------------------------INQKL 287

  Fly   219 IPDDKDQSKKKTRTIKACLNPVWNETLTYDLKPEDKDRRILIEVWDWDRTSRNDFMGALSFGISE 283
            :.:...|...|:.|
Zfish   288 LAEALTQVSTKSST--------------------------------------------------- 301

  Fly   284 IIKNPTNGWFKLLTQDEGEYYNV-----PCADDEQDLLKLKQKPSQKKPMVMRSDTNTHTSSKKD 343
              |.|.|.     |||.|.|.:.     |...|......:.:..|.:.|..:...|.
Zfish   302 --KRPDNN-----TQDVGVYQDFNKSPGPDVTDGTPYGHIWEGSSPRPPSRITHQTR-------- 351

  Fly   344 MIRATDFNFIKVLGKGSFGKVLLAERKGSEELYAIKILKKDVIIQDDDVECTMIEKRVLALGEKP 408
             |.|..|.|.|||||||||||||||.||:.|.:|:|.|||||::.||||||||:|||||||....
Zfish   352 -ITAEHFIFHKVLGKGSFGKVLLAELKGTGEWFAVKALKKDVVLMDDDVECTMVEKRVLALAWDN 415

  Fly   409 PFLVQLHSCFQTMDRLFFVMEYVNGGDLMFQIQQFGKFKEPVAVFYAAEIAAGLFFLHTKGILYR 473
            |||..|:|.|||.:.|||||||:|||||||.||:.|:|....|.||||||..||.|||:|||:||
Zfish   416 PFLTHLYSTFQTKEHLFFVMEYLNGGDLMFHIQEKGRFDLYRATFYAAEIVCGLQFLHSKGIIYR 480

  Fly   474 DLKLDNVLLDADGHVKIADFGMCKENIVGDKTTKTFCGTPDYIAPEIILYQPYGKSVDWWAYGVL 538
            |||||||:||.|||:|||||||||||:.||....|||||||||||||:|.|.|..|||||::|||
Zfish   481 DLKLDNVMLDGDGHIKIADFGMCKENVFGDNRATTFCGTPDYIAPEILLGQQYSFSVDWWSFGVL 545

  Fly   539 LYEMLVGQPPFDGEDEEELFAAITDHNVSYPKSLSKEAKEACKGFLTKQPNKRLGCGSSGEEDVR 603
            :||||:||.||.|:||:|||.:|......||:.:..:.::..:....:.|::|||...    ::|
Zfish   546 VYEMLIGQSPFHGDDEDELFESIRMDTPHYPRWILLDTRDMLERLFERDPSRRLGIVG----NIR 606

  Fly   604 LHPFFRRIDWEKIENREVQPPFKPKIKHRKDVSNFDKQFTSEKTDLTPTDKVFMMNLDQSEFVGF 668
            .|.||:.::|..:|.|||.||||||:|...|.||||::|.|||..|:..:|..:.::||..|.||
Zfish   607 GHSFFKTVNWAALEGREVDPPFKPKVKAPNDCSNFDREFLSEKPRLSHCEKGLIDSMDQCAFAGF 671

  Fly   669 SYMNPE 674
            |::||:
Zfish   672 SFINPK 677

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pkc53E	NP_725626.1	C1_cPKC_rpt1	44..110	CDD:410383	29/70 (41%)
		C1_cPKC_rpt2	120..173	CDD:410386	30/52 (58%)
		C2_PKC_alpha_gamma	177..307	CDD:175992	13/134 (10%)
		STKc_cPKC	353..672	CDD:270739	186/318 (58%)
prkcda	NP_999873.1	C1_1	160..209	CDD:278556	25/57 (44%)
		C1_1	232..284	CDD:278556	30/94 (32%)
		S_TKc	357..611	CDD:214567	157/257 (61%)
		STKc_nPKC_delta	361..676	CDD:173710	186/318 (58%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000117
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R891
SonicParanoid	1	1.000	-	-		X125
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.940