Protein Alignment Pkc53E and Pkcdelta

DIOPT Version :10

• Sequence 1: NP_725626.1
• Gene: Pkc53E / 48311
• FlyBaseID: FBgn0003091
• Length: 679
• Species: Drosophila melanogaster
• Sequence 2: NP_572797.3
• Gene: Pkcdelta / 32191
• FlyBaseID: FBgn0287828
• Length: 1894
• Species: Drosophila melanogaster
• Alignment Length: 606
• Identity: 232/606 - (38%)
• Similarity: 310/606 - (51%)
• Gaps: 99/606 - (16%)

  Fly   153 CDMNVHARCKENVPSLC-----------------GCDHTERRGRIYLEINVKENLLTVQIKEGRN 200
            |..:|.|...:.:||..                 ..|::...|...|..::|:.|...:.|:...
  Fly  1298 CLRDVDAELDDYIPSSAENSQEDDDDDDDGSGSSSDDYSSVDGCANLSASMKKKLRKEKKKQKAK 1362

  Fly   201 LIPMDPNGLSDPYVKVKLIPDDKDQSKKKT--RTIKACLNPVW-NETLTYDLK------------ 250
            ..........||:.|:|:...:|...|::.  ..:.|...|:| .|.:.|..:
  Fly  1363 AAAAAEAKRFDPHKKIKIDTTNKCYVKEEAPRYPLVATPRPLWKREKIVYSDENTDDESGSEEGS 1427

  Fly   251 ----PEDKDRRILIEVWDWDRTSRNDFMGALSFGISE-------IIKNPTNGWFKLLTQDEGEYY 304
                .||.|          |.:...:.....|...||       :.|..::....:|........
  Fly  1428 GGSLDEDSD----------DESGGEECSSTSSSASSEDLDAVAMVTKAGSSNATTVLDSSNSSGS 1482

  Fly   305 N-----VPCADDEQDLLKLKQKPSQKKPMVMRSDT---------NTHTSSKKDMIRAT------- 348
            |     ||.|.....    ....:...|.::|..|         .|..||.|.|:..:
  Fly  1483 NAGTLSVPSAGSGSG----GGASTSSSPSIIRMSTCSNDSGFEGGTAPSSPKKMLETSYTYSQFQ 1543

  Fly   349 ---------------------DFNFIKVLGKGSFGKVLLAERKGSEELYAIKILKKDVIIQDDDV 392
                                 ||:|:.||||||||||||||.:.:...||||.|||||:::||||
  Fly  1544 KSGRFTAPATVIPRFKNYSVDDFHFLAVLGKGSFGKVLLAELRDTTYYYAIKCLKKDVVLEDDDV 1608

  Fly   393 ECTMIEKRVLALGEKPPFLVQLHSCFQTMDRLFFVMEYVNGGDLMFQIQQFGKFKEPVAVFYAAE 457
            :.|:||::|||||.|.|:|..|...|||...|||||||:|||||||.||:.|:|.|..|.||.||
  Fly  1609 DSTLIERKVLALGTKHPYLCHLFCTFQTESHLFFVMEYLNGGDLMFHIQESGRFSEERARFYGAE 1673

  Fly   458 IAAGLFFLHTKGILYRDLKLDNVLLDADGHVKIADFGMCKENIVGDKTTKTFCGTPDYIAPEIIL 522
            |.:||.|||.|||:||||||||||||.:|||:||||||||..|..|||..:|||||||:|||||.
  Fly  1674 IISGLKFLHKKGIIYRDLKLDNVLLDYEGHVRIADFGMCKLQIYLDKTADSFCGTPDYMAPEIIK 1738

  Fly   523 YQPYGKSVDWWAYGVLLYEMLVGQPPFDGEDEEELFAAITDHNVSYPKSLSKEAKEACKGFLTKQ 587
            .:.|.::||||::||||||||:||.||.|.||:|||.:|.:....:|..:|.||....||.|.|.
  Fly  1739 GEKYNQNVDWWSFGVLLYEMLIGQSPFSGCDEDELFWSICNEIPWFPVYISAEATGILKGLLEKD 1803

  Fly   588 PNKRLGCGSSGEEDVRLHPFFRRIDWEKIENREVQPPFKPKIKHRKDVSNFDKQFTSEKTDLTPT 652
            ..||:|...|...|:..|.|||.|||..:|.|:::|||||::||..|...||:.||.|:..|||.
  Fly  1804 YTKRIGSQYSPAGDIADHIFFRPIDWGLLEKRQIEPPFKPQVKHPLDTQYFDRVFTRERVRLTPI 1868

  Fly   653 DKVFMMNLDQSEFVGFSYMNP 673
            ||..:.::||.:|.||:|.||
  Fly  1869 DKEILASMDQKQFHGFTYTNP 1889

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pkc53E	NP_725626.1	C1_cPKC_rpt1	44..110	CDD:410383
		C1_cPKC_rpt2	120..173	CDD:410386	5/36 (14%)
		C2_PKC_alpha_gamma	177..307	CDD:175992	26/160 (16%)
		STKc_cPKC	353..672	CDD:270739	184/318 (58%)
Pkcdelta	NP_572797.3	Herpes_BLLF1	<802..1131	CDD:282904
		STKc_nPKC_theta_like	1570..1889	CDD:270744	184/318 (58%)