Protein Alignment Pkc53E and Dmpk

DIOPT Version :10

• Sequence 1: NP_725626.1
• Gene: Pkc53E / 48311
• FlyBaseID: FBgn0003091
• Length: 679
• Species: Drosophila melanogaster
• Sequence 2: XP_063117378.1
• Gene: Dmpk / 308405
• RGDID: 1309825
• Length: 687
• Species: Rattus norvegicus
• Alignment Length: 355
• Identity: 126/355 - (35%)
• Similarity: 197/355 - (55%)
• Gaps: 36/355 - (10%)

  Fly   341 KKDMIRATDFNFIKVLGKGSFGKVLLAERKGSEELYAIKILKKDVIIQDDDVECTMIEKRVLALG 405
            |:..::..||..:||:|:|:|.:|.:.:.|.:.::||:||:.|..:::..:|.|...|:.||..|
  Rat    62 KEVRLQRDDFEILKVIGRGAFSEVAVVKMKQTGQVYAMKIMNKWDMLKRGEVSCFREERDVLVKG 126

  Fly   406 EKPPFLVQLHSCFQTMDRLFFVMEYVNGGDLMFQIQQFG-KFKEPVAVFYAAEIAAGLFFLHTKG 469
            :: .::.|||..||..:.|:.||||..||||:..:.:|| :....:|.||.|||...:..:|..|
  Rat   127 DR-RWITQLHFAFQDENYLYLVMEYYVGGDLLTLLSKFGERIPAEMARFYLAEIVMAIDSVHRLG 190

  Fly   470 ILYRDLKLDNVLLDADGHVKIADFGMCKENIVGDKTTKTF--CGTPDYIAPEIIL-------YQP 525
            .::||:|.||:|||..||:::||||.|.: :..|.|.::.  .|||||::|||:.       ...
  Rat   191 YVHRDIKPDNILLDRCGHIRLADFGSCLK-LQPDGTVRSLVAVGTPDYLSPEILQAVGGGPGAGS 254

  Fly   526 YGKSVDWWAYGVLLYEMLVGQPPFDGEDEEELFAAITDH--NVSYPKS---LSKEAKEACKGFLT 585
            ||...||||.||..|||..||.||..:...|.:|.|..:  ::|.|::   :.:||::..:|.|.
  Rat   255 YGPECDWWALGVFAYEMFYGQTPFYADSTAETYAKIVHYREHLSLPRADMGVPEEAQDLIRGLLC 319

  Fly   586 KQPNK-RLGCGSSGEEDVRLHPFFRRIDWEKIENREVQPPFKPKIKHRKDVSNFD---KQFTS-- 644
              |.: |||.|.:|  |.:.||||..:|||.:  |:..|||.|..:...|..|||   .:.|:
  Rat   320 --PAEIRLGRGGAG--DFQKHPFFFGLDWEGL--RDSVPPFTPDFEGATDTCNFDVVEDRLTAMV 378

  Fly   645 ----EKTDLTPTDKVFMMNLDQSEFVGFSY 670
                |.......|....::|   .|||:||
  Rat   379 SGGGETLSDMQEDMALGVHL---PFVGYSY 405

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pkc53E	NP_725626.1	C1_cPKC_rpt1	44..110	CDD:410383
		C1_cPKC_rpt2	120..173	CDD:410386
		C2_PKC_alpha_gamma	177..307	CDD:175992
		STKc_cPKC	353..672	CDD:270739	123/343 (36%)
Dmpk	XP_063117378.1	None