Protein Alignment Pkc53E and gad8

DIOPT Version :10

• Sequence 1: NP_725626.1
• Gene: Pkc53E / 48311
• FlyBaseID: FBgn0003091
• Length: 679
• Species: Drosophila melanogaster
• Sequence 2: NP_588010.1
• Gene: gad8 / 2539206
• PomBaseID: SPCC24B10.07
• Length: 569
• Species: Schizosaccharomyces pombe
• Alignment Length: 530
• Identity: 180/530 - (33%)
• Similarity: 270/530 - (50%)
• Gaps: 85/530 - (16%)

  Fly   186 VKENLLTVQIKEGRNL------IPMD--------------PNGLSD----------PYVKVKLIP 220
            |:..||.|.|.|.|||      :|.:              .||...          ||:.|:.
pombe    64 VQPGLLQVTIIEARNLKLPSGHVPANYGVSIDNSLLAPPLSNGSGHARSRSHAWWLPYIVVEF-- 126

  Fly   221 DDKDQSKKKTRTIKACLNPVWNETLTYDLKPEDKDRRILIEVWDWDRTSR------ND-FMGALS 278
             ||::.........:..||.|:...|:|:....|   :.:.::....:||      || |:|.:.
pombe   127 -DKNEILVDALNTASLENPCWDYQATFDVSRYSK---LSLNIYLRSSSSRSRNGMGNDAFLGGIK 187

  Fly   279 FGISEIIKNPTNGWFKLLTQDEGEYYNVPCADDEQDL-LKLKQKPSQKKPMVMRSDTNTHTSSKK 342
            ...|.|:...|:.|             ||......:| :::..||:|..|:.:.:
pombe   188 LSPSFIVNKLTDEW-------------VPLHGGSGELRVQMLYKPNQSTPLTIDA---------- 229

  Fly   343 DMIRATDFNFIKVLGKGSFGKVLLAERKGSEELYAIKILKKDVIIQDDDVECTMIEKRVLALGEK 407
                   |..:||:||||||||:...::.:..:||:|.:||..|:...:|:.|:.|:.|||....
pombe   230 -------FELLKVVGKGSFGKVMQVRKRDTSRIYALKTMKKAHIVSRSEVDHTLAERTVLAQVNN 287

  Fly   408 PPFLVQLHSCFQTMDRLFFVMEYVNGGDLMFQIQQFGKFKEPVAVFYAAEIAAGLFFLHTKGILY 472
             ||:|.|...||:..:|:.|:.:||||:|...:|:.|.|....|.||.||:...|..||...::|
pombe   288 -PFIVPLKFSFQSPGKLYLVLAFVNGGELFHHLQREGCFDTYRAKFYIAELLVALECLHEFNVIY 351

  Fly   473 RDLKLDNVLLDADGHVKIADFGMCKENIVGDKTTKTFCGTPDYIAPEIILYQPYGKSVDWWAYGV 537
            ||||.:|:|||..||:.:.|||:||.|:.....|.||||||:|:|||::|...|.|.||||..||
pombe   352 RDLKPENILLDYTGHIALCDFGLCKLNMAKTDRTNTFCGTPEYLAPELLLGHGYTKVVDWWTLGV 416

  Fly   538 LLYEMLVGQPPFDGEDEEELFAAITDHNVSYPKSLSKEAKEACKGFLTKQPNKRLGCGSSGEEDV 602
            |||||:.|.|||..|:..|::..|....:.:|.::.::||:...|.||:.|.||||.|  |.:::
pombe   417 LLYEMITGLPPFYDENINEMYRKILQDPLRFPDNIDEKAKDLLSGLLTRAPEKRLGSG--GAQEI 479

  Fly   603 RLHPFFRRIDWEKIENREVQPPFKPKIKHRKDVSNFDKQFTSEKTDLTPTDKV----FMMNLDQS 663
            :.||||..|||:|:..:::||||||.::...|.||||.:||||    .|.|.|    .:....|.
pombe   480 KNHPFFDDIDWKKLCAKKIQPPFKPSVESAIDTSNFDSEFTSE----IPMDSVVADSHLSETVQQ 540

  Fly   664 EFVGFSYMNP 673
            .|..:||..|
pombe   541 RFANWSYQRP 550

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pkc53E	NP_725626.1	C1_cPKC_rpt1	44..110	CDD:410383
		C1_cPKC_rpt2	120..173	CDD:410386
		C2_PKC_alpha_gamma	177..307	CDD:175992	33/157 (21%)
		STKc_cPKC	353..672	CDD:270739	138/322 (43%)
gad8	NP_588010.1	YPK1_N_like	66..225	CDD:212165	38/177 (21%)
		STKc_YPK1_like	235..547	CDD:270737	135/318 (42%)