DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pkc53E and F48G7.10

DIOPT Version :9

Sequence 1:	NP_725626.1	Gene:	Pkc53E / 48311	FlyBaseID:	FBgn0003091	Length:	679	Species:	Drosophila melanogaster
Sequence 2:	NP_503273.1	Gene:	F48G7.10 / 185998	WormBaseID:	WBGene00018621	Length:	168	Species:	Caenorhabditis elegans

Alignment Length:	169	Identity:	63/169 - (37%)
Similarity:	76/169 - (44%)	Gaps:	35/169 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 ENKMKSRLRKGALKKKNVFNVKDHCFIARFFKQPTFCSHCKDFICGYQSGYAWMGFGKQGFQCQV 87
            ||....|...|:    .:..:..|.|.|....|||.|:.|...|         .|.||||::|..
Worm     8 ENPFIDRQLDGS----KIHEISGHRFKATALVQPTCCAICSKLI---------YGLGKQGYRCLG 59

  Fly    88 CSYVVHKRCHEYVTFIC----------PGKDKGIDS-------DSP-----KTQHNFEPFTYAGP 130
            |..|||||||..:...|          |.::...||       .||     .|.|:|....|..|
Worm    60 CETVVHKRCHSLINDRCNFGPSSPRQPPPQELSSDSGELRHRIPSPTEPQVSTNHHFNKHFYTRP 124

  Fly   131 TFCDHCGSLLYGIYHQGLKCSACDMNVHARCKENVPSLC 169
            ||||||||||||:..||::||.|..|||.||||.....|
Worm   125 TFCDHCGSLLYGLSKQGVQCSDCLANVHHRCKEKAVHNC 163

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pkc53E	NP_725626.1	C1_cPKC_rpt1	44..110	CDD:410383	25/75 (33%)
		C1_cPKC_rpt2	120..173	CDD:410386	29/50 (58%)
		C2_PKC_alpha_gamma	177..307	CDD:175992
		STKc_cPKC	353..672	CDD:270739
F48G7.10	NP_503273.1	C1_1	27..76	CDD:278556	23/57 (40%)
F48G7.10	NP_503273.1	C1_1	114..166	CDD:278556	29/50 (58%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000117
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910