Protein Alignment Pkc53E and pkc-3

DIOPT Version :9

• Sequence 1: NP_725626.1
• Gene: Pkc53E / 48311
• FlyBaseID: FBgn0003091
• Length: 679
• Species: Drosophila melanogaster
• Sequence 2: NP_495011.1
• Gene: pkc-3 / 173914
• WormBaseID: WBGene00004034
• Length: 597
• Species: Caenorhabditis elegans
• Alignment Length: 677
• Identity: 223/677 - (32%)
• Similarity: 307/677 - (45%)
• Gaps: 195/677 - (28%)

  Fly     9 GDPQQQGAEGEAVGENKMKSRLRKGALKKKNVFNVKDHCFIARFFKQPTFCSHCKDFICGYQSGY 73
            |.|:..|...:  ||:  |:..|:||.:.|.::....|.|.|:...:...|..|.|:|
 Worm    95 GKPELPGLPCQ--GED--KTVYRRGARRWKKIYLYNGHRFQAKRLNRRIQCFICHDYI------- 148

  Fly    74 AWMGFGKQGFQCQVCSYVVHKRCHEYVTFICPGKDKGIDSDSPKTQHNFEPFTYAGPTFCDHCGS 138
             | |.|:|||:|..|...|||:||.:|.                                .|||.
 Worm   149 -W-GIGRQGFRCVDCRLCVHKKCHRHVR--------------------------------THCGQ 179

  Fly   139 LLYGIYHQGLKCSACDMNVHARCKENVPSLCGCDHTERRGRIYLEINVKENLLTVQIKEGRNLIP 203
            .|                                                        :|.|:||
 Worm   180 AL--------------------------------------------------------QGPNIIP 188

  Fly   204 MDPNGLSDPYVKVKLIPDDKDQSKKKTRTIKACLNPVWNETLTYDLKPEDKDRRILIEVWDWDRT 268
            |.|...|       |.....:.|...||:.....|..::|   ::::..
 Worm   189 MAPASGS-------LKGARSNTSSSTTRSGGGIDNGAFHE---HEIESP---------------- 227

  Fly   269 SRNDFMGALSFGISEIIKNPTNGWFKLLTQDEGEYYNVPCADDEQDLLKLKQKPSQKKPMVMRSD 333
                  |:.|...|..:    ||
 Worm   228 ------GSTSHDASRAM----NG------------------------------------------ 240

  Fly   334 TNTHTSSKKDMIRATDFNFIKVLGKGSFGKVLLAERKGSEELYAIKILKKDVIIQDDDVECTMIE 398
                ..|.|..:...||..:.|:|:||:.||:.||...:.::|||||:||::..:|:|::....|
 Worm   241 ----NGSSKWAVSLNDFRLLTVIGRGSYAKVVQAEHVSTRQIYAIKIIKKEMFNEDEDIDWVQTE 301

  Fly   399 KRVLALGEKPPFLVQLHSCFQTMDRLFFVMEYVNGGDLMFQIQQFGKFKEPVAVFYAAEIAAGLF 463
            |.|.......||||.|||||||..|||||:|:|.||||||.:||..|..|..|.||:.||...|.
 Worm   302 KSVFEAASNYPFLVGLHSCFQTESRLFFVIEFVPGGDLMFHMQQQRKLPEEHARFYSGEIILALH 366

  Fly   464 FLHTKGILYRDLKLDNVLLDADGHVKIADFGMCKENIVGDKTTKTFCGTPDYIAPEIILYQPYGK 528
            |||::||:||||||||||:||:||:|:.|:|||||||.....|.||||||:||||||:....||.
 Worm   367 FLHSRGIIYRDLKLDNVLIDAEGHIKLTDYGMCKENIKDGDLTSTFCGTPNYIAPEILRGDEYGF 431

  Fly   529 SVDWWAYGVLLYEMLVGQPPFD------GED--EEELFAAITDHNVSYPKSLSKEAKEACKGFLT 585
            ||||||.|||::||:.|:.|||      .|:  |:.||..|.:..:..|:|||..|....||||.
 Worm   432 SVDWWALGVLMFEMMAGRSPFDIVGMQNSEENTEDYLFQIILERQIRIPRSLSVRASGILKGFLN 496

  Fly   586 KQPNKRLGCG---SSGEEDVRLHPFFRR-IDWEKIENREVQPPFKPKIKHRKDVSNFDKQFTSEK 646
            |.|.:||||.   :.|..|::.|.|||. ||||.:|.:.|.||:.|.::..:|:::||.|||.|.
 Worm   497 KDPTERLGCKLDINEGLRDMKEHQFFRGFIDWEALEQKAVAPPYHPAVESDRDLTHFDHQFTDEL 561

  Fly   647 TDLTPTDKVFMMNLDQSEFVGFSYMNP 673
            ..|:|.:...:..:|||||.||.|:||
 Worm   562 PQLSPDNPDVIARIDQSEFDGFEYVNP 588

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pkc53E	NP_725626.1	C1_cPKC_rpt1	44..110	CDD:410383	21/65 (32%)
		C1_cPKC_rpt2	120..173	CDD:410386	4/52 (8%)
		C2_PKC_alpha_gamma	177..307	CDD:175992	18/129 (14%)
		STKc_cPKC	353..672	CDD:270739	164/330 (50%)
pkc-3	NP_495011.1	PB1_aPKC	13..95	CDD:99725	223/677 (33%)
		C1_1	128..178	CDD:278556	22/90 (24%)
		S_TKc	253..522	CDD:214567	136/268 (51%)
		PKc_like	257..586	CDD:304357	163/328 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D614710at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920