Protein Alignment Pkc53E and Pdk1

DIOPT Version :10

• Sequence 1: NP_725626.1
• Gene: Pkc53E / 48311
• FlyBaseID: FBgn0003091
• Length: 679
• Species: Drosophila melanogaster
• Sequence 2: XP_061502914.1
• Gene: Pdk1 / 1281703
• VectorBaseID: AGAMI1_004980
• Length: 635
• Species: Anopheles gambiae
• Alignment Length: 362
• Identity: 114/362 - (31%)
• Similarity: 161/362 - (44%)
• Gaps: 63/362 - (17%)

  Fly   323 SQKKPMVMRSDTNTHTSSKKDMIRATDFNFIKVLGKGSFGKVLLAERKGSEELYAIKILKKDVII 387
            |....:||.|:.:|..|| ...:...||.|.|:||:|||..|.||:...:.:.||||:.:|.:|:
Mosquito    19 STTNTVVMDSNRSTKPSS-GHRLNPNDFYFGKMLGEGSFSCVYLAKEVRTSKKYAIKVCEKRLIL 82

  Fly   388 QDDDVECTMIEKRVL-ALGEKPPFLVQLHSCFQTMDRLFFVMEYVNGGDLMFQIQQFGKFKEPVA 451
            ::...|....|:.|| .|..:|.|| .|:..||...:|:|||.|...|.|:..:.: ..|....|
Mosquito    83 REKKQEYVKREREVLNRLTGRPGFL-GLYCTFQDRSKLYFVMTYACNGTLLTLLSR-PSFTLDCA 145

  Fly   452 VFYAAEIAAGLFFLHTKGILYRDLKLDNVLLDADGHVKIADFGMCK------------------- 497
            .||||||...|..:|...||:||:|.:|:|||...||.|||||..|
Mosquito   146 RFYAAEILLALETMHDMAILHRDIKPENILLDERMHVLIADFGSSKLDYKEEDEDEEEQADSGCE 210

  Fly   498 ------------------ENIVG-----DKT----------------TKTFCGTPDYIAPEIILY 523
                              :.::|     |.|                .::|.||..|::|||:..
Mosquito   211 EKKDAPSSPTMSTARKHAQRVLGAEYDDDDTDDNGEDAPPATRPPNKRRSFVGTAQYVSPEILTG 275

  Fly   524 QPYGKSVDWWAYGVLLYEMLVGQPPFDGEDEEELFAAITDHNVSYPKSLSKEAKEACKGFLTKQP 588
            .|...:.|.|:||..||:|:.|..||....|..:|..|....|||..|....||:.....|..:.
Mosquito   276 TPSSPASDLWSYGCTLYQMVCGVSPFRAASEYLIFKMILRCQVSYADSFDHTAKDLVTRLLHLEQ 340

  Fly   589 NKRLGCGSSGE-EDVRLHPFFRRIDWEKIENREVQPP 624
            .||||...|.. ..:|.|.||..||:|.:..:....|
Mosquito   341 AKRLGARDSPRYRTIRQHAFFEGIDFEHLRQQPAPMP 377

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pkc53E	NP_725626.1	C1_cPKC_rpt1	44..110	CDD:410383
		C1_cPKC_rpt2	120..173	CDD:410386
		C2_PKC_alpha_gamma	177..307	CDD:175992
		STKc_cPKC	353..672	CDD:270739	104/332 (31%)
Pdk1	XP_061502914.1	None