Protein Alignment Pkc53E and prkcdb

DIOPT Version :9

• Sequence 1: NP_725626.1
• Gene: Pkc53E / 48311
• FlyBaseID: FBgn0003091
• Length: 679
• Species: Drosophila melanogaster
• Sequence 2: NP_001352166.1
• Gene: prkcdb / 100150844
• ZFINID: ZDB-GENE-111129-1
• Length: 685
• Species: Danio rerio
• Alignment Length: 662
• Identity: 275/662 - (41%)
• Similarity: 364/662 - (54%)
• Gaps: 146/662 - (22%)

  Fly    31 RKGALKKKNVFNVKDHCFIARFFKQPTFCSHCKDFICGYQSGYAWMGFGKQGFQCQVCSYVVHKR 95
            |:||:|:..|..:|:|.|.|.|||||||||.|::|:        | |..|||::|:.|:..:||:
Zfish   145 RRGAIKQAKVHFIKNHEFTATFFKQPTFCSVCREFV--------W-GLNKQGYKCRQCNAAIHKK 200

  Fly    96 CHEYVTFICPG----------KDKGIDSDSPKTQHNFEPFTYAGPTFCDHCGSLLYGIYHQGLKC 150
            |.:.:...|.|          :.:....|.|   |.|:...|..|||||||||||:|:..|||||
Zfish   201 CIDKIIGRCTGTATNSRDTMFQKERFKIDMP---HRFKTNNYMSPTFCDHCGSLLWGMVKQGLKC 262

  Fly   151 SACDMNVHARCKENVPSLCGCDH---TERRGRIYLEINVKE---NLLTVQIKEG--RNLIPMDPN 207
            ..|.||||.:|:..|.:|||.:.   .|...::.|:.:.|.   .|..:.|.:.  :| :|.||:
Zfish   263 EDCGMNVHHKCQTKVANLCGINQKLLAEALNQVSLKSSTKRPDPTLSEIGIYQAIDKN-VPADPS 326

  Fly   208 GLSDPYVKVKLIPDDKDQSKKKTRTIKACLNPVWNETLTYDLKPEDKDRRILIEVWDWDRTSRND 272
            .....|.|.                              :|:.|......|:..|    |.|.||
Zfish   327 AEGSQYGKF------------------------------WDITPAVPASTIVSTV----RVSLND 357

  Fly   273 FMGALSFGISEIIKNPTNGWFKLLTQDEGEYYNVPCADDEQDLLKLKQKPSQKKPMVMRSDTNTH 337
            |:
Zfish   358 FV--------------------------------------------------------------- 359

  Fly   338 TSSKKDMIRATDFNFIKVLGKGSFGKVLLAERKGSEELYAIKILKKDVIIQDDDVECTMIEKRVL 402
                          |.|||||||||||:|||.||..:.:|||.|||||::.||||||||:|||||
Zfish   360 --------------FQKVLGKGSFGKVMLAELKGKGQYFAIKALKKDVVLMDDDVECTMVEKRVL 410

  Fly   403 ALGEKPPFLVQLHSCFQTMDRLFFVMEYVNGGDLMFQIQQFGKFKEPVAVFYAAEIAAGLFFLHT 467
            ||..:.|||..|:..||:.:.|||||||:|||||||.||..|:|....|.||||||..||.:||:
Zfish   411 ALAWENPFLTHLYCTFQSKEHLFFVMEYLNGGDLMFHIQDKGRFDLYRATFYAAEIICGLQYLHS 475

  Fly   468 KGILYRDLKLDNVLLDADGHVKIADFGMCKENIVGDKTTKTFCGTPDYIAPEIILYQPYGKSVDW 532
            |||:|||||||||:||.|||:|||||||||||::|:....|||||||||||||:|.|.|..||||
Zfish   476 KGIVYRDLKLDNVMLDKDGHIKIADFGMCKENMIGENRATTFCGTPDYIAPEILLGQKYSFSVDW 540

  Fly   533 WAYGVLLYEMLVGQPPFDGEDEEELFAAITDHNVSYPKSLSKEAKEACKGFLTKQPNKRLGCGSS 597
            |::||||||||:||.||.|:||:|||.:|......||:.::||||:..:....:.|.:|||...
Zfish   541 WSFGVLLYEMLIGQSPFQGDDEDELFDSIRMDVPHYPRWITKEAKDLLEKLFERDPTRRLGVVG- 604

  Fly   598 GEEDVRLHPFFRRIDWEKIENREVQPPFKPKIKHRKDVSNFDKQFTSEKTDLTPTDKVFMMNLDQ 662
               ::|.|.||:.|:|..:|.|||.||||||:|...|.||||::|.|||..|:.:||..:.::||
Zfish   605 ---NIRGHAFFKTINWPALEKREVSPPFKPKVKSSSDCSNFDREFLSEKPRLSQSDKNLIDSMDQ 666

  Fly   663 SEFVGFSYMNPE 674
            :.|.|||::||:
Zfish   667 TAFAGFSFINPK 678

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pkc53E	NP_725626.1	C1_cPKC_rpt1	44..110	CDD:410383	27/75 (36%)
		C1_cPKC_rpt2	120..173	CDD:410386	30/52 (58%)
		C2_PKC_alpha_gamma	177..307	CDD:175992	19/134 (14%)
		STKc_cPKC	353..672	CDD:270739	188/318 (59%)
prkcdb	NP_001352166.1	C1_1	160..209	CDD:278556	24/57 (42%)
		C1_1	232..284	CDD:278556	30/51 (59%)
		PKc_like	362..677	CDD:328722	188/318 (59%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000117
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R891
SonicParanoid	1	1.000	-	-		X125
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.940