Protein Alignment Pkc53E and prkcq

DIOPT Version :9

• Sequence 1: NP_725626.1
• Gene: Pkc53E / 48311
• FlyBaseID: FBgn0003091
• Length: 679
• Species: Drosophila melanogaster
• Sequence 2: XP_012813823.2
• Gene: prkcq / 100038268
• XenbaseID: XB-GENE-487643
• Length: 699
• Species: Xenopus tropicalis
• Alignment Length: 662
• Identity: 281/662 - (42%)
• Similarity: 372/662 - (56%)
• Gaps: 128/662 - (19%)

  Fly    31 RKGALKKKNVFNVKDHCFIARFFKQPTFCSHCKDFICGYQSGYAWMGFGKQGFQCQVCSYVVHKR 95
            |:||:|:..|..||.|.|.|.||.||||||.|.:|:        | |..|||:||:.|:..:||:
 Frog   142 RRGAMKQAKVHQVKCHEFTATFFPQPTFCSVCHEFV--------W-GLNKQGYQCRQCNAAIHKK 197

  Fly    96 CHEYVTFICPGKDKGIDS------------DSPKTQHNFEPFTYAGPTFCDHCGSLLYGIYHQGL 148
            |.:.|...|.|  ..::|            |.|   |.|:...|..||||:|||:||:|:..|||
 Frog   198 CIDKVIAKCTG--SAVNSKETVLHKERFKIDMP---HRFKVNNYRSPTFCEHCGTLLWGLARQGL 257

  Fly   149 KCSACDMNVHARCKENVPSLCGCDHTERRGRIYLEINVKENLLTVQIKEGRNLIPMDPNGLSDPY 213
            ||:.|:||||.:|...|.:|||               |.:.|:.
 Frog   258 KCAECNMNVHHKCAVKVANLCG---------------VNQKLMA--------------------- 286

  Fly   214 VKVKLIPDDKDQSKKKTRTIKACLNPVWNETLTYDLKPEDKDRRILIEVWDWDRTSRNDFMGALS 278
                                         |.|.            :||....||..|:
 Frog   287 -----------------------------EALA------------MIETTQQDRRQRD------- 303

  Fly   279 FGISEII--KNPTNGWFKLLTQDEGEYYNVPCADD----EQDLLKLKQKPSQKKPMVMRSDTNTH 337
               ||.|  :.|.|......|||:....::.....    |..:..:|.:.|..:|     :....
 Frog   304 ---SEFIYREGPVNVGPTTNTQDQPIVLSIKKESQGISWESPIESIKVQESPPEP-----ELKIE 360

  Fly   338 TSSKKDMIRATDFNFIKVLGKGSFGKVLLAERKGSEELYAIKILKKDVIIQDDDVECTMIEKRVL 402
            .||.:..:..:||...|:|||||||||.|||.|.:.:.:|||:|||||::.||||||||:|||||
 Frog   361 QSSCQIKVTFSDFVLHKMLGKGSFGKVFLAELKRTNQFFAIKVLKKDVVLMDDDVECTMVEKRVL 425

  Fly   403 ALGEKPPFLVQLHSCFQTMDRLFFVMEYVNGGDLMFQIQQFGKFKEPVAVFYAAEIAAGLFFLHT 467
            :|..:.|||..|:..|||.:.|||||||:|||||||.||...||..|.|.||||||..||.|||:
 Frog   426 SLAWEHPFLTHLYCTFQTKEHLFFVMEYLNGGDLMFHIQSCHKFDLPRATFYAAEIVCGLQFLHS 490

  Fly   468 KGILYRDLKLDNVLLDADGHVKIADFGMCKENIVGDKTTKTFCGTPDYIAPEIILYQPYGKSVDW 532
            ||::||||||||:|||.:||:||||||||||:::||..|.|||||||||||||:|.|.|..||||
 Frog   491 KGVVYRDLKLDNILLDMEGHIKIADFGMCKESMLGDAKTSTFCGTPDYIAPEILLGQKYNYSVDW 555

  Fly   533 WAYGVLLYEMLVGQPPFDGEDEEELFAAITDHNVSYPKSLSKEAKEACKGFLTKQPNKRLGCGSS 597
            |::||||||||:||.||.|.||||||.:|...|..||:.||.|||:.......::|.:|||.
 Frog   556 WSFGVLLYEMLIGQSPFHGIDEEELFQSIRMDNPMYPRFLSMEAKDILIMLFVREPERRLGV--- 617

  Fly   598 GEEDVRLHPFFRRIDWEKIENREVQPPFKPKIKHRKDVSNFDKQFTSEKTDLTPTDKVFMMNLDQ 662
             :.|:|.|.||:.|||.::||||::||||||:|...|.|||||:|.:||..|:.:::..:.::||
 Frog   618 -KGDIRQHCFFQHIDWGRLENREIEPPFKPKVKSADDWSNFDKEFLNEKPRLSSSERTLINSMDQ 681

  Fly   663 SEFVGFSYMNPE 674
            :.|..||::||:
 Frog   682 NMFNNFSFVNPK 693

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pkc53E	NP_725626.1	C1_cPKC_rpt1	44..110	CDD:410383	28/65 (43%)
		C1_cPKC_rpt2	120..173	CDD:410386	28/52 (54%)
		C2_PKC_alpha_gamma	177..307	CDD:175992	17/131 (13%)
		STKc_cPKC	353..672	CDD:270739	189/318 (59%)
prkcq	XP_012813823.2	C1_nPKC_theta-like_rpt1	150..210	CDD:410384	30/70 (43%)
		C1_nPKC_theta-like_rpt2	229..278	CDD:410387	25/48 (52%)
		STKc_nPKC_theta	367..697	CDD:270770	193/331 (58%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000117
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R891
SonicParanoid	1	1.000	-	-		X125
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.940