Protein Alignment Pkc53E and pkn1b

DIOPT Version :9

• Sequence 1: NP_725626.1
• Gene: Pkc53E / 48311
• FlyBaseID: FBgn0003091
• Length: 679
• Species: Drosophila melanogaster
• Sequence 2: NP_001082929.1
• Gene: pkn1b / 100007897
• ZFINID: ZDB-GENE-070424-87
• Length: 909
• Species: Danio rerio
• Alignment Length: 550
• Identity: 201/550 - (36%)
• Similarity: 283/550 - (51%)
• Gaps: 98/550 - (17%)

  Fly   167 SLCGCDHTE-------RRGRIYLEINVKENLLTVQIKEGRNLIPMDPNGLSDPYVKVKLIPDDKD 224
            |||...:.:       :|.|:.||:. .:.||..::.....:|...|          :|....|.
Zfish   411 SLCALKYLKLEDFLDNQRHRVQLELE-PQGLLLAEVMFFNPVIERGP----------RLQRQRKV 464

  Fly   225 QSKKKTRTIKACLNPVWNETLTYDLKPEDKDRRILIEVWDWDRTSRNDFMGALSFGISEIIKNPT 289
            .||::.   ||.|                :.:::.:::..|.|..:|            .|..||
Zfish   465 FSKQQG---KAFL----------------RAKQMNVDMATWVRLLKN------------AITIPT 498

  Fly   290 NGWFKLLTQDEGEYYNVPCADDEQDLLKLKQKPSQKKPMVMRSDTNTHTSSKKDMIRAT------ 348
            :.:    ||....::    :..|..:.|: |...:..|.|.|  .|||||:..|..||.
Zfish   499 HNY----TQHSHTHH----SSSEISIQKI-QLDGESPPSVTR--RNTHTSATVDFGRAAEPVSPP 552

  Fly   349 ----------------------------DFNFIKVLGKGSFGKVLLAERKGSEELYAIKILKKDV 385
                                        ||..|.|||:|.||||||:|.:.|..|||||.|||..
Zfish   553 GPAPPERVVRSISHLSQRRSSKSALCLQDFRMIAVLGRGHFGKVLLSEYRRSGNLYAIKALKKGD 617

  Fly   386 IIQDDDVECTMIEKRVLAL--GEKPPFLVQLHSCFQTMDRLFFVMEYVNGGDLMFQIQQFGKFKE 448
            |:..|:||..|.|||:...  ..:.||||.|.:||||.:.:.|||||..|||||..|.. ..|.|
Zfish   618 IVARDEVESLMCEKRIFETVNSAQHPFLVNLFACFQTPEHVCFVMEYTAGGDLMMHIHA-DVFSE 681

  Fly   449 PVAVFYAAEIAAGLFFLHTKGILYRDLKLDNVLLDADGHVKIADFGMCKENIVGDKTTKTFCGTP 513
            ..:|||:|.:..||.|||...|:||||||||:|||.:|:|||||||:|||.:.....|.||||||
Zfish   682 TRSVFYSACVVLGLQFLHDNKIVYRDLKLDNLLLDTEGYVKIADFGLCKEGMGHGDRTSTFCGTP 746

  Fly   514 DYIAPEIILYQPYGKSVDWWAYGVLLYEMLVGQPPFDGEDEEELFAAITDHNVSYPKSLSKEAKE 578
            :::|||::....|.::||||..|||:|||:||:.||.|:||||:|.:|.:..|.||:.||.||..
Zfish   747 EFLAPEVLTDTSYTRAVDWWGLGVLIYEMMVGESPFPGDDEEEVFDSIVNDEVRYPRFLSTEAIG 811

  Fly   579 ACKGFLTKQPNKRLGCGSSGEEDVRLHPFFRRIDWEKIENREVQPPFKPKIKHRKDVSNFDKQFT 643
            ..:..|.:.|.:|||.|....||::..||||.:||:.:..|:|.|||.|.:.:.:||||||.:||
Zfish   812 IMRRLLRRNPERRLGSGEKDAEDIKKQPFFRNMDWDALLQRKVPPPFVPAVANSEDVSNFDAEFT 876

  Fly   644 SEKTDLT-PTDKVFMMNLDQSEFVGFSYMN 672
            :|...|| |.::..:...||..|..|.|::
Zfish   877 NEAPTLTPPRERRSLSRKDQDYFKDFDYVS 906

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pkc53E	NP_725626.1	C1_cPKC_rpt1	44..110	CDD:410383
		C1_cPKC_rpt2	120..173	CDD:410386	3/5 (60%)
		C2_PKC_alpha_gamma	177..307	CDD:175992	23/129 (18%)
		STKc_cPKC	353..672	CDD:270739	159/321 (50%)
pkn1b	NP_001082929.1	HR1_PKN_1	15..80	CDD:212012
		HR1_PKN1_2	99..176	CDD:212020
		HR1_PKN1_3	180..253	CDD:212026
		C2	364..447	CDD:301316	9/36 (25%)
		STKc_PKN	582..907	CDD:270741	160/325 (49%)
		S_TKc	582..841	CDD:214567	132/259 (51%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170583320
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840