DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment mus101 and slf1

DIOPT Version :9

Sequence 1:	NP_524909.1	Gene:	mus101 / 48309	FlyBaseID:	FBgn0002878	Length:	1425	Species:	Drosophila melanogaster
Sequence 2:	XP_012823830.1	Gene:	slf1 / 100495961	XenbaseID:	XB-GENE-983324	Length:	911	Species:	Xenopus tropicalis

Alignment Length:	138	Identity:	47/138 - (34%)
Similarity:	71/138 - (51%)	Gaps:	13/138 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly  1244 DSCTHLLCERPNRGEKMLACIAAGKWILNIQYIEQSHARGDFLDETLYEWGNPKAINLPTLAPEE 1308
            ::||||:.:.|.|.||.||..:||||:|...|:..|..||.:||||:||||    ..:...:|..
Frog    48 ENCTHLIAKNPCRSEKWLAACSAGKWVLIKDYVINSVQRGRWLDETIYEWG----YRIERHSPYS 108

  Fly  1309 EPIAAAVHRWRTELSACG-GGAFSDHRV--ILSMNERSGAPIRNVLRAGGACILEPTTPFSKDPV 1370
            ..:.:|..|||..|:..| .|||...:|  ::...::.......|||||.|.|.      :.:.:
Frog   109 PQMQSAPKRWREHLTRTGVKGAFRKWKVAILVDKGQKQREAFERVLRAGQAIIC------NAEEL 167

  Fly  1371 AKSASHCF 1378
            .:..:|.|
Frog   168 HEEVTHVF 175

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mus101	NP_524909.1	BRCT	118..188	CDD:278934
		BRCT	216..290	CDD:278934
		BRCT	397..472	CDD:278934
		BRCT	707..778	CDD:278934
		BRCT	1210..1279	CDD:237994	16/34 (47%)
slf1	XP_012823830.1	BRCT	16..>67	CDD:294035	9/18 (50%)
		ANK	655..784	CDD:238125
		ANK repeat	659..690	CDD:293786
		Ank_2	663..750	CDD:289560
		ANK repeat	692..723	CDD:293786
		ANK repeat	726..750	CDD:293786
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1061
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.030