Protein Alignment ATP1B3 and CG11703

DIOPT Version :10

• Sequence 1: NP_001670.1
• Gene: ATP1B3 / 483
• HGNCID: 806
• Length: 279
• Species: Homo sapiens
• Sequence 2: NP_650792.1
• Gene: CG11703 / 42307
• FlyBaseID: FBgn0038690
• Length: 353
• Species: Drosophila melanogaster
• Alignment Length: 311
• Identity: 67/311 - (21%)
• Similarity: 115/311 - (36%)
• Gaps: 88/311 - (28%)

Human     3 KNEKKSLNQSLAEWKLFIYNPTTGEFLGRTAKSWGLILLFYLVFYGFLAALFSFTMWV-MLQTLN 66
            :|::....:.| .|...|::....:..||||..|..|..||||.|..:..:.:|.:.: ||..::
  Fly    20 RNQETRRKKDL-PWSKRIFDIDEHKLFGRTALGWMRITGFYLVLYALIVCIVAFWLGIFMLAIID 83

Human    67 DEVPKYRDQIPSPGLMVFP---KPVTALEYTFSRSDPTSYAGYIEDLKKFLKPYTLEEQKNLTVC 128
            ...|::..  ..|||.:.|   :.|.|. :|...|:....|..|:|.              |...
  Fly    84 PNKPRWLK--GPPGLSMVPNQNRSVLAY-FTHIMSEVNPIADRIDDF--------------LNKL 131

Human   129 PDGAL-----FEQKGPVYVACQFPISLLQACSGMNDPDFGYSQGNPCILVKMNRIIGLKPE---- 184
            .|.|:     |.|                      |..:||:...|.:.:|:|::||..||
  Fly   132 NDNAIDFFADFNQ----------------------DTTWGYATEKPTVFIKLNKVIGYVPETYDT 174

Human   185 --------------------GVPR--IDCVSKNEDIPNVAVYPHNGMIDLKYFPYYGKKLHVGYL 227
                                ..|:  |.|...|...|.:..||.         ||:....::..:
  Fly   175 PDDLPKEAPASLQDTVGKLGNTPKIWITCEVTNGPKPEMVFYPG---------PYFEASENMRGV 230

Human   228 QPLVAVQVSFAPNNTGKEVTVECKIDGSANLKSQDDRDKFLGRVMFKITAR 278
            ..:||:|::..|.|.  :....||: .:.|:...||. :.:|.:.|.::.|
  Fly   231 TRVVAIQMNKMPENA--KTFFSCKV-WARNIPIDDDY-QGMGIIKFALSMR 277

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ATP1B3	NP_001670.1	Na_K_ATPase_bet	1..279	CDD:273446	67/311 (22%)
		immunoglobulin-like. /evidence=ECO:0000250	186..279		22/95 (23%)
CG11703	NP_650792.1	Na_K-ATPase	40..267	CDD:471796	60/278 (22%)