Protein Alignment ATP1B3 and CG33310

DIOPT Version :10

• Sequence 1: NP_001670.1
• Gene: ATP1B3 / 483
• HGNCID: 806
• Length: 279
• Species: Homo sapiens
• Sequence 2: NP_995718.2
• Gene: CG33310 / 2768910
• FlyBaseID: FBgn0053310
• Length: 876
• Species: Drosophila melanogaster
• Alignment Length: 326
• Identity: 67/326 - (20%)
• Similarity: 109/326 - (33%)
• Gaps: 125/326 - (38%)

Human     2 TKNEKKSLNQSL-------AEWKLFIYNPTTGEFLGRTAKSWGLILLFYLVFYGFLAALFSFTMW 59
            ||.::::..:..       .||:...:|...|::..|....| |..|.:.|.|.....:||...:
  Fly   563 TKEDRRTYYKGCEYHFPGRTEWRRLFFNKIHGKYKLRRPSHW-LYTLVFSVLYILFVIIFSMAWF 626

Human    60 VMLQ-TLNDEVPKYRDQIP----SP-GLMVFPKPVTALEYTFSRSDPT----SYAGYIEDLKKFL 114
            ..:: ..:.:||..:...|    :| |....||.|     :|...:.|    .|||.:
  Fly   627 DFIKDDASRKVPMIKMAQPFISFTPIGPRTNPKAV-----SFDPRNSTEVMEKYAGIM------- 679

Human   115 KPYTLEEQKNLTVCPDGALFEQKG-----PVYVACQFPISLLQACSGMNDPDFGYSQGNPCILVK 174
                             ||.|:.|     |.:..|            ..:..|||..|.||:.:|
  Fly   680 -----------------ALLEKYGDYGHNPRFGTC------------TANEKFGYPSGEPCVFLK 715

Human   175 MNRIIGLKPE-------------------GVPR----------------IDCVS-KNEDI----- 198
            :|||||.|.|                   .:.|                |.|.| |::::
  Fly   716 VNRIIGFKTEPYINSDELVKAKIDEVEFTALKRLLENTTTEEGHLNRTWITCRSDKDKNVLIEFH 780

Human   199 PNVAVYPHNGMID--LKYFPYYGKKLHVGYLQPLVAVQVSFAPNNTGKEVTVECKIDGSANLKSQ 261
            |..|:......|:  ::|....|||..             |.||:..:.|.::.|     |||:.
  Fly   781 PEPAIRTEYTDIEEKIEYIANEGKKSF-------------FGPNDVNRIVALKIK-----NLKAN 827

Human   262 D 262
            :
  Fly   828 E 828

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ATP1B3	NP_001670.1	Na_K_ATPase_bet	1..279	CDD:273446	67/326 (21%)
		immunoglobulin-like. /evidence=ECO:0000250	186..279		20/101 (20%)
CG33310	NP_995718.2	Na_K-ATPase	<703..846	CDD:471796	34/144 (24%)