Protein Alignment DNaseII and Dnase2b

DIOPT Version :10

• Sequence 1: NP_650672.1
• Gene: DNaseII / 48228
• FlyBaseID: FBgn0000477
• Length: 366
• Species: Drosophila melanogaster
• Sequence 2: NP_064341.3
• Gene: Dnase2b / 56629
• MGIID: 1913283
• Length: 354
• Species: Mus musculus
• Alignment Length: 345
• Identity: 107/345 - (31%)
• Similarity: 160/345 - (46%)
• Gaps: 20/345 - (5%)

  Fly    22 KVSCKDEAGNDVDWWHLYKLPKHYQHNDLGKDTSGLKYLYVTSQNYDTWQMSGKFISDPLSLPAQ 86
            ::||::|.|..|||:..|||||   ......:.:||:|||:.|.. .||..|...|:...|...:
Mouse    25 EISCRNEYGEAVDWFIFYKLPK---RTSKASEEAGLQYLYLDSTR-QTWNKSLYLINSTRSALGR 85

  Fly    87 TLNPLND---DPSHTLLAAYNDQQPNGTVFS-SGGHAKGVVASDGETAIWIVHSVPKFPTIPDYS 147
            ||..|.|   ..:.|....|||..|....:| ..|||||::..:.....|::|||||||.:..|.
Mouse    86 TLQHLYDTHNSTNDTAYLIYNDGVPGSVNYSRQYGHAKGLLVWNRTQGFWLIHSVPKFPPVHGYE 150

  Fly   148 YPTSGEQYAQSMLCVTLKGEDLEKVGQILVYNEPHFYYQRNPLATRSDELFPSLERALHGQWRTE 212
            |||||.:|.|:.:|:|......|::...|:..:|:.|....|.......::  :.|........:
Mouse   151 YPTSGRRYGQTGICITFGYSQFEEIDFQLLVLQPNIYSCFIPSTFHWKLIY--MPRMCANSSSLK 213

  Fly   213 SPFQKDLEVRSLDGKKFRLFGKSGRANVELYADVVAPTLDVSLFVEAWRDGAGNLPNSCDKSDKV 277
            .|.:...|:.|..|..|..|.||.....:::...:|..|...|..:.|:.....||::|.....|
Mouse   214 IPVRYLAELHSAQGLNFVHFAKSSFYTDDIFTGWIAQKLKTHLLAQTWQKKKQELPSNCSLPYHV 278

  Fly   278 LNVESISNPELSVDFKTTQDHSKWAVSRPTGILIYHWRVGGGDWICVGDINRQEGQLHRGGGTVC 342
            .|::||.....|. |.:.||||||.||         .:.....|.|:||:||...|..||||.:|
Mouse   279 YNIKSIGVTSKSY-FSSRQDHSKWCVS---------IKGSANRWTCIGDLNRSLHQALRGGGFIC 333

  Fly   343 HKSARVSNLYRQLVTNYDKC 362
            .|:..:...:.:|...|..|
Mouse   334 TKNHYIYQAFHKLYLRYGFC 353

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DNaseII	NP_650672.1	DNase_II	24..351	CDD:460868	104/330 (32%)
Dnase2b	NP_064341.3	DNase_II	27..342	CDD:460868	104/330 (32%)