Protein Alignment DNaseII and dnase2b

DIOPT Version :9

• Sequence 1: NP_650672.1
• Gene: DNaseII / 48228
• FlyBaseID: FBgn0000477
• Length: 366
• Species: Drosophila melanogaster
• Sequence 2: NP_001011305.2
• Gene: dnase2b / 496759
• XenbaseID: XB-GENE-980313
• Length: 354
• Species: Xenopus tropicalis
• Alignment Length: 374
• Identity: 114/374 - (30%)
• Similarity: 186/374 - (49%)
• Gaps: 42/374 - (11%)

  Fly     6 FVLLFVWFFYQNEAKSKVSCKDEAGNDVDWWHLYKLPKHYQHNDLGKDTSGLKYLYVTSQNYDTW 70
            |.:|::  ...:...:::||::|||:.:||:.:||||....:...|   |||.|||:.|.|.: |
 Frog     7 FAVLYL--IAMSMVAAEISCRNEAGDPIDWFVVYKLPMLKMNGSTG---SGLDYLYMDSTNQE-W 65

  Fly    71 QMSGKFISDPLSLPAQTLNPL--NDDPSHTLLAAYNDQQPNGTVFSSGGHAKGVVASDGETAIWI 133
            |:|...|:...|...|.|..|  :.|.::|:...|||..||.|..:..||.||::..|.....|:
 Frog    66 QISKFQINTTKSAVGQVLQQLYQDYDKNNTVYMIYNDAPPNVTNSTRKGHTKGILFFDNSQGFWL 130

  Fly   134 VHSVPKFPTIPD--YSYPTSGEQYAQSMLCVTLKGEDLEKVGQILVYNEPHFY-------YQRNP 189
            :||||.||..|:  |.||::|:::.|:.:|||.:..:.:::...|:|..|:.|       ||:
 Frog   131 IHSVPHFPPYPEDGYGYPSTGKRFGQTAICVTYQYNEFKEIATQLLYYNPNVYNCSVPDIYQK-- 193

  Fly   190 LATRSDELFPSLERAL--HGQWRTESPFQKDLEVRSLDGKKFRLFGKSGRANVELYADVVAPTLD 252
                  |::...:..|  |..|...:   :..::.|..|:.|..|.||.....:::|..:|..|.
 Frog   194 ------EMWMLHKICLGGHFPWIDST---RLTQLNSARGEVFLNFAKSKYFIDDIFAAWIAQKLR 249

  Fly   253 VSLFVEAWRDGAGNLPNSCDKSDKVLNVESISNPELSVDFKTTQDHSKWAVSRPTGILIYHWRVG 317
            .::.||:|: ....|.::|.....|.|:..|..|..|. |:|..|||||.||:....|
 Frog   250 TNMLVESWQ-SRQQLSSNCSLQYHVYNINRIGLPTQST-FQTFYDHSKWCVSQSNEDL------- 305

  Fly   318 GGDWICVGDINRQEGQLHRGGGTVCHKSARVSNLYRQLVTNYDKCAQQE 366
               |.|:||:||...|..|.||.:|.::..:...:|.:|..|..|...|
 Frog   306 ---WTCIGDLNRHPAQTRRSGGFICTQNKHIYTAFRNMVLYYKNCTDTE 351

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DNaseII	NP_650672.1	PLDc_DNaseII_1	21..164	CDD:197219	56/146 (38%)
		DNase_II	24..360	CDD:281283	109/348 (31%)
		PLDc_DNaseII_2	213..362	CDD:197220	43/148 (29%)
dnase2b	NP_001011305.2	DNase_II	25..336	CDD:367426	105/337 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	176	1.000	Domainoid score	I3554
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H1052
Inparanoid	1	1.050	179	1.000	Inparanoid score	I3900
OMA	1	1.010	-	-		QHG54389
OrthoDB	1	1.010	-	-		D422272at33208
OrthoFinder	1	1.000	-	-		FOG0002558
OrthoInspector	1	1.000	-	-		otm48829
Panther	1	1.100	-	-	O	PTHR10858
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2694
SonicParanoid	1	1.000	-	-		X1683
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	12	12.110