DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment DNaseII and crn-6

DIOPT Version :9

Sequence 1:	NP_650672.1	Gene:	DNaseII / 48228	FlyBaseID:	FBgn0000477	Length:	366	Species:	Drosophila melanogaster
Sequence 2:	NP_499061.2	Gene:	crn-6 / 176316	WormBaseID:	WBGene00000799	Length:	378	Species:	Caenorhabditis elegans

Alignment Length:	331	Identity:	111/331 - (33%)
Similarity:	170/331 - (51%)	Gaps:	28/331 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 CKDEAGNDVDWWHLYKLPKHYQHNDLGKDTSGLKYLYVTSQNYDTWQMSGKFISDPLSLPAQTLN 89
            |||..|::|||:..||||..:.|.|....::|..:||....| ..|::..:.:....:....||.
Worm    21 CKDNNGSNVDWFVFYKLPHLWNHPDNVPISNGTGFLYFDVNN-KNWKLMPQGMDVENNAVYYTLQ 84

  Fly    90 P-LNDDPSHTLLAAYNDQQPNGTVFS-SGGHAKGVVASDGETAIWIVHSVPKFPTIPDYSYPTSG 152
            . .|.:.:.|....|||:.|:.|::| |.||||||...|..|..|::||:||||:...:.:|::.
Worm    85 QYYNSNMNTTFSYMYNDEWPDSTIWSNSSGHAKGVTVFDQYTGFWMIHSIPKFPSKDMFRFPSNA 149

  Fly   153 EQYAQSMLCVTLKGEDLEKVGQILVYNEPHFYYQRNPLATRSDELFPSLERALHGQWRTESPFQK 217
            ..|.|..:|::.....|..:.|.|.|... |.||.| |.......||.|.:..:.::....|...
Worm   150 HYYGQMGICISYNTVSLATIAQQLFYYNT-FTYQFN-LPQSFANQFPVLSQLKNKEYNKSPPLTS 212

  Fly   218 DLEVRSLDGKKFRLFGKSGRANVELYADVVAPTLDVSLFVEAWRDGAG---NLPNSCDKS--DKV 277
            ...::||.|:.||.|.|:|....:||:|.|.|||..|:.||.|...:|   |||:.||.:  ...
Worm   213 TKVLKSLGGQHFRHFAKTGEWGKDLYSDFVGPTLKSSIKVETWNHQSGDEYNLPSVCDPNHVQST 277

  Fly   278 LNVESISNPELSVDFKTTQDHSKWAV------SRPTGILIYHWRVGGGDWICVGDINRQEGQLHR 336
            ::.:.|..| .::|:.:.:||||:.|      |:|.           ..::|:||||||..|:||
Worm   278 MSAKYIRLP-YAIDYSSYEDHSKFVVAYSESSSKPP-----------IPYVCIGDINRQSHQIHR 330

  Fly   337 GGGTVC 342
            ||||:|
Worm   331 GGGTMC 336

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DNaseII	NP_650672.1	PLDc_DNaseII_1	21..164	CDD:197219	48/140 (34%)
		DNase_II	24..360	CDD:281283	111/331 (34%)
		PLDc_DNaseII_2	213..362	CDD:197220	51/141 (36%)
crn-6	NP_499061.2	PLDc_DNaseII_1	17..161	CDD:197219	48/140 (34%)
		DNase_II	20..352	CDD:281283	111/331 (34%)
		PLDc_DNaseII_2	208..356	CDD:197220	51/141 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160162429
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H1052
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S5194
OMA	1	1.010	-	-		QHG54389
OrthoDB	1	1.010	-	-		D422272at33208
OrthoFinder	1	1.000	-	-		FOG0002558
OrthoInspector	1	1.000	-	-		otm14184
orthoMCL	1	0.900	-	-		OOG6_104320
Panther	1	1.100	-	-	O	PTHR10858
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1683
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	11	10.810