Protein Alignment DNaseII and Dnase2a

DIOPT Version :9

• Sequence 1: NP_650672.1
• Gene: DNaseII / 48228
• FlyBaseID: FBgn0000477
• Length: 366
• Species: Drosophila melanogaster
• Sequence 2: NP_034192.1
• Gene: Dnase2a / 13423
• MGIID: 1329019
• Length: 353
• Species: Mus musculus
• Alignment Length: 372
• Identity: 122/372 - (32%)
• Similarity: 185/372 - (49%)
• Gaps: 29/372 - (7%)

  Fly     1 MRSLCFVLLFVWFFYQNEAKSKVSCKDEAGNDVDWWHLYKLPKHYQHNDLGKDTSGLKYLYVTSQ 65
            |.:|..:||....:...||   :||..::|..|||:.:||||.|....|..|   ||.|.|: .|
Mouse     1 MATLRSLLLAALLWVPAEA---LSCYGDSGQPVDWFVVYKLPAHSGSRDTPK---GLTYKYM-DQ 58

  Fly    66 NYDTWQMSGKFISDPLSLPAQTLNPL-NDDPSHTLLAAYNDQQPNGTVF--SSG-GHAKGVVASD 126
            |.|.||....:|:.......::|.|| ..:.|......||||.|..:..  |:| ||.|||:..|
Mouse    59 NSDGWQDGVGYINSSEGAVGRSLQPLYRKNSSQLAFLLYNDQPPKSSSARDSTGHGHTKGVLLLD 123

  Fly   127 GETAIWIVHSVPKFP---TIPDYSYPTSGEQYAQSMLCVTLKGEDLEKVGQILVYNEPHFYYQRN 188
            .|...|:|||||:||   :...|::|.:.:.:.|::|||:|......::|:.|.|..|..|..:
Mouse   124 QEGGFWLVHSVPRFPPPASSGAYTWPPNAQTFGQTLLCVSLPFTQFARIGKQLTYTYPLVYDHK- 187

  Fly   189 PLATRSDELFPSLERALHGQWRTESPFQKDLEVRSLDGKKFRLFGKSGRANVELYADVVAPTLDV 253
             |.....:..|.||..:..|.....|:...:.:.|..|..|:.|.|.|:...:||:..:|..|..
Mouse   188 -LEGFFAQKLPDLETVIKNQHVLHEPWNSSVILTSQAGATFQSFAKFGKFGDDLYSGWLAEALGT 251

  Fly   254 SLFVEAWRDGAGNLPNSCDKSDKVLNVESISNPELS-VDFKTTQDHSKWAVSRPTGILIYHWRVG 317
            :|.|:.|::..|.||::|..:.:||:|.....|..| :.|..|:|||||.|:..
Mouse   252 NLQVQFWQNSPGILPSNCSGAYQVLDVTQTGFPGPSRLTFSATEDHSKWCVAPQ----------- 305

  Fly   318 GGDWICVGDINRQEGQLHRGGGTVCHKSARVSNLYRQLVTNYDKCAQ 364
             |.|.||||:||.:.:.||||||||.:.......::.||.::..|.:
Mouse   306 -GPWACVGDMNRNKAETHRGGGTVCTQLPSFWKAFQSLVKDWKPCIE 351

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DNaseII	NP_650672.1	PLDc_DNaseII_1	21..164	CDD:197219	55/149 (37%)
		DNase_II	24..360	CDD:281283	115/343 (34%)
		PLDc_DNaseII_2	213..362	CDD:197220	49/149 (33%)
Dnase2a	NP_034192.1	PLDc_SF	19..178	CDD:301585	59/165 (36%)
		DNase_II	21..346	CDD:281283	115/342 (34%)
		PLDc_SF	211..349	CDD:301585	49/149 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	186	1.000	Domainoid score	I3342
eggNOG	1	0.900	-	-		E1_KOG3825
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	187	1.000	Inparanoid score	I3901
Isobase	1	0.950	-	0	Normalized mean entropy	S5194
OMA	1	1.010	-	-		QHG54389
OrthoDB	1	1.010	-	-		D422272at33208
OrthoFinder	1	1.000	-	-		FOG0002558
OrthoInspector	1	1.000	-	-		otm43658
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR10858
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2694
SonicParanoid	1	1.000	-	-		X1683
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.920