DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SNU13 and RpS12

DIOPT Version :9

Sequence 1:	NP_001003796.1	Gene:	SNU13 / 4809	HGNCID:	7819	Length:	128	Species:	Homo sapiens
Sequence 2:	NP_729866.1	Gene:	RpS12 / 39480	FlyBaseID:	FBgn0286213	Length:	139	Species:	Drosophila melanogaster

Alignment Length:	117	Identity:	28/117 - (23%)
Similarity:	52/117 - (44%)	Gaps:	11/117 - (9%)

- Green bases have known domain annotations that are detailed below.

Human     1 MTEADVN-PKAYPLADA--HLTKKLLDLVQQSCNYKQLRKGANEATKTLNRGISEFIVMAADAEP 62
            |.:.||: |.|.|:.|.  .:...|.:::::|.....|..|.::|.|.|::..:...::|...:.
  Fly     1 MADVDVDVPSAAPVLDGAMDINTALQEVLKKSLIADGLVHGIHQACKALDKRQAVLCILAESFDE 65

Human    63 LEIILHLPLLCEDKNVPYVFVRSKQALGRACGV--------SRPVIACSVTI 106
            ......:..||.:..:|.:.|.|.:.||...|:        .|.|..|||.:
  Fly    66 PNYKKLVTALCNEHQIPLIRVDSHKKLGEWSGLCKIDKEGKPRKVCGCSVVV 117

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SNU13	NP_001003796.1	SNU13	7..128	CDD:411046	25/111 (23%)
		Interaction with U4 snRNA and U4atac snRNA. /evidence=ECO:0000269\|PubMed:17412961, ECO:0000269\|PubMed:21784869	36..48		4/11 (36%)
		Important for U4 snRNA-binding. /evidence=ECO:0000269\|PubMed:10545122	96..128		5/11 (45%)
RpS12	NP_729866.1	Ribosomal_L7Ae	23..118	CDD:396000	21/95 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1358
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810