DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SNU13 and RpL7A

DIOPT Version :9

Sequence 1:	NP_001003796.1	Gene:	SNU13 / 4809	HGNCID:	7819	Length:	128	Species:	Homo sapiens
Sequence 2:	NP_001284944.1	Gene:	RpL7A / 31588	FlyBaseID:	FBgn0014026	Length:	271	Species:	Drosophila melanogaster

Alignment Length:	86	Identity:	29/86 - (33%)
Similarity:	45/86 - (52%)	Gaps:	6/86 - (6%)

- Green bases have known domain annotations that are detailed below.

Human    12 PLADAHLTKKLLDLVQQSCNYKQLRK------GANEATKTLNRGISEFIVMAADAEPLEIILHLP 70
            |||.....||:.:...:..:.:..:|      |.|..||.:.:..::.:|:|.|.:|||::|.||
  Fly   112 PLAKKLRLKKIAEAKAKGKDVEPKKKPSYVSAGTNTVTKLIEQKKAQLVVIAHDVDPLELVLFLP 176

Human    71 LLCEDKNVPYVFVRSKQALGR 91
            .||....|||..|:.|..|||
  Fly   177 ALCRKMGVPYCIVKGKARLGR 197

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SNU13	NP_001003796.1	SNU13	7..128	CDD:411046	29/86 (34%)
		Interaction with U4 snRNA and U4atac snRNA. /evidence=ECO:0000269\|PubMed:17412961, ECO:0000269\|PubMed:21784869	36..48		5/17 (29%)
		Important for U4 snRNA-binding. /evidence=ECO:0000269\|PubMed:10545122	96..128
RpL7A	NP_001284944.1	PTZ00365	18..271	CDD:240382	29/86 (34%)
RpL7A	NP_001284944.1	Ribosomal_L7Ae	37..257	CDD:294400	29/86 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1358
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810