Protein Alignment Su(z)12 and suz12

DIOPT Version :10

• Sequence 1: NP_730465.1
• Gene: Su(z)12 / 48071
• FlyBaseID: FBgn0020887
• Length: 900
• Species: Drosophila melanogaster
• Sequence 2: XP_012822185.1
• Gene: suz12 / 779745
• XenbaseID: XB-GENE-997462
• Length: 729
• Species: Xenopus tropicalis
• Alignment Length: 816
• Identity: 290/816 - (35%)
• Similarity: 423/816 - (51%)
• Gaps: 179/816 - (21%)

  Fly     1 MAPAKKREKDSNPDGSAANGIIGLTHGAPDASNAGSTVPPTAEGQVKLNGHQQEQELFLQAFEKP 65
            |||.|.       .||:|      ..|.|.|  |.|.:|..   :.|:...|.:.||||||||||
 Frog     1 MAPQKH-------GGSSA------PSGKPSA--AASLLPVR---KPKMEQIQADHELFLQAFEKP 47

  Fly    66 TQIYRYLRNRHETNPIFLNRTLSYMKERMSRNNKKRISFQVNSMLESI-----TQKSEAVSQNYL 125
            |||||:||.|:...||||:|||:||..|.||:|.||.:|:||.:|..:     .|:|.:||. :|
 Frog    48 TQIYRFLRTRNLIAPIFLHRTLTYMSHRNSRSNAKRKTFKVNDLLLKVEKMKGDQESHSVSA-HL 111

  Fly   126 HVIYDSLHEKLPARLDNESGEDLLQEQLLCEAGESVSVETTLYKITRSKRK-------------- 176
            .:.:.....|:.....|...|.           .||::|..|.|:...|||
 Frog   112 QLTFTGFFHKIDKPSQNSENEQ-----------SSVTLEVLLVKVCHKKRKARYNDSVAVQASPR 165

  Fly   177 ----DSTLDFQELLSKCS-----------QIVYNPKDRVGEHAT---ISIPLQTMRPMGEQHTL- 222
                |..|:.|..|...|           |:..||:....:.:|   :::......| ...|.:
 Frog   166 SAGNDPKLEGQHFLGDVSCPIRQVPTGKKQVPLNPELNPAKPSTFPSLAVSSNEFEP-SNSHMVK 229

  Fly   223 -YKLLFRIKVLSPSTCN-------DEN---AETPPNKRSR------PNEKMFGSELILYEKSSGF 270
             |.||||:........|       :||   :|.||.:|.|      ..:|.|.:::.:::|:...
 Frog   230 SYSLLFRVTRQGRRDFNGLTNGETNENIDVSEEPPARRKRNSSNRDEGDKTFVAQMTVFDKNRRL 294

  Fly   271 -ITEGEYEAMLQPLNSTSIKSFSPKKCTWETMPD-SYIPLSLTYDVYQQSPMLKFHLTLSNEQLP 333
             :.:||||..:|.:....:   :.|:.||||:.| ..:|   .::.:.|.|.|:|.|..:|: .|
 Frog   295 QLLDGEYEVAMQEMEDCPV---NKKRATWETILDGKRLP---PFETFSQGPTLQFTLRWTND-TP 352

  Fly   334 EMISAPELQRYVQHLDAVAE--MNYNNNNYNNNNNCSGLKNG-------------SGGGNSTVCK 383
            :..:||           :|:  ...|:.:....:..|.:|..             .......|..
 Frog   353 DKSTAP-----------IAKPLATRNSESLPQEHKPSSVKPAQTVAVKESLSSDLQARKERDVSS 406

  Fly   384 TTPEHIQIVYNFMYSNNTRQQTEYTQELNCPWCGLDCLRLYALLKHLKLCHAR--FNFTYQPAGS 446
            ...:.::|.|.|:|:||||||||...:|:||||.|:|.:||:|||||||||:|  ||:.|.|  .
 Frog   407 EPRQKLRIFYQFLYNNNTRQQTEARDDLHCPWCTLNCRKLYSLLKHLKLCHSRFIFNYVYHP--K 469

  Fly   447 GARIDVTINDAYDGSYAGSPYDLAGPSGSSFARTCGPVRRTSVTSLMVCRPRRQKTCLDEFLELD 511
            ||||||:||:.|||||||:|.|:....|.:|:|. |||:||.:|.::||||:|.|..:.||||.:
 Frog   470 GARIDVSINECYDGSYAGNPQDIHRQPGFAFSRN-GPVKRTPITHILVCRPKRTKASMSEFLESE 533

  Fly   512 EDEISNQRSYITGHNRLYHHTETCLPVHPKELDIDSEGESDPLWLRQKTIQMIDEFSDVNEGEKE 576
            :.|:..||:|.:||||||.|::||||:.|:|:|:|||.|.||.|||:|||..|:|||||||||||
 Frog   534 DGEVEQQRTYSSGHNRLYFHSDTCLPLRPQEMDVDSEDEKDPEWLREKTITQIEEFSDVNEGEKE 598

  Fly   577 LMKLWNLHVMRHGFVGDCQLPIACEMFLDAKGTEIVRKNLYRNFILHMCSLFDYGLIAAETVYKT 641
            :||:||||||:|||:.|.|:...|.:|:|..|.:|::|||.|||:||:.|:.|:.||:..|:.|.
 Frog   599 VMKMWNLHVMKHGFIADNQMNHGCMLFVDNYGPQIIQKNLCRNFMLHLVSMHDFNLISITTIDKA 663

  Fly   642 VQKLQGLLSKYAAGQELMQR-QREEQLKYWLDVGMHKKQEDPKTLKSPQKPAPPADQA------S 699
            |.:|          :|:.|: :|:|.|                        |||:|:|      :
 Frog   664 VSRL----------REIQQKVERDECL------------------------APPSDEAFEEPNRT 694

  Fly   700 TSSASTSGSGSGSS--------SMQPPKRMPAHLKR 727
            |||:|:....:|..        |.||||    |.|:
 Frog   695 TSSSSSFMETNGKDRVVENDCVSGQPPK----HSKK 726

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Su(z)12	NP_730465.1	ZnB-Zn_SUZ12-like	54..>82	CDD:459250	19/27 (70%)
		C2_II_SUZ12	154..328	CDD:467848	52/225 (23%)
		ZnB-Zn_SUZ12	<388..459	CDD:439246	43/72 (60%)
		VEFS-Box	511..644	CDD:462864	75/132 (57%)
suz12	XP_012822185.1	ZnB-Zn_SUZ12-like	36..>64	CDD:459250	19/27 (70%)
		C2_II_SUZ12	109..348	CDD:467848	56/257 (22%)
		ZnB-Zn_SUZ12	<409..482	CDD:439246	43/74 (58%)
		VEFS-box_SUZ12	549..670	CDD:439216	69/130 (53%)