Protein Alignment Su(z)12 and Suz12

DIOPT Version :9

• Sequence 1: NP_730465.1
• Gene: Su(z)12 / 48071
• FlyBaseID: FBgn0020887
• Length: 900
• Species: Drosophila melanogaster
• Sequence 2: XP_038943572.1
• Gene: Suz12 / 688041
• RGDID: 1593621
• Length: 738
• Species: Rattus norvegicus
• Alignment Length: 690
• Identity: 264/690 - (38%)
• Similarity: 389/690 - (56%)
• Gaps: 90/690 - (13%)

  Fly    15 GSAANGIIGLTHGAPDASNAGSTVPPTAEGQVKLNGHQQEQELFLQAFEKPTQIYRYLRNRHETN 79
            |....|..|.:..:..|:.||:.|.|..  :.|:...|.:.|||||||||||||||:||.|:...
  Rat    44 GGGCGGGGGYSASSSSAAAAGAAVLPVK--KPKMEHVQADHELFLQAFEKPTQIYRFLRTRNLIA 106

  Fly    80 PIFLNRTLSYMKERMSRNNKKRISFQVNSMLESI-----TQKSEAVSQNYLHVIYDSLHEKLPAR 139
            ||||:|||:||..|.||.|.||.:|:|:.||..:     .|:|.::|. :|.:.:.....|....
  Rat   107 PIFLHRTLTYMSHRNSRTNIKRKTFKVDDMLSKVEKMKGEQESHSLSA-HLQLTFTGFFHKNDKP 170

  Fly   140 LDNESGEDLLQEQLLCEAGESVSVETTLYKITRSKRKDSTLDFQELLSKCSQIVYNP---KDRVG 201
            ..|...|.           .||::|..|.|:...||||.:...:::.:...|:..||   :.:.|
  Rat   171 SQNSENEQ-----------NSVTLEVLLVKVCHKKRKDVSCPIRQVPTGKKQVPLNPDLNQTKPG 224

  Fly   202 EHATISIPLQTMRPMGEQHTL--YKLLFRIKVLSPSTCNDE-NAETPPN-----------KRSRP 252
            ...::::......| ...|.:  |.||||:........|.. |.||..|           ||:|.
  Rat   225 NFPSLAVSSNEFEP-SNSHMVKSYSLLFRVTRPGRREFNGMINGETNENIDVSEELPARRKRNRE 288

  Fly   253 N-EKMFGSELILYEKSSGF-ITEGEYEAMLQPLNSTSIKSFSPKKCTWETMPD-SYIPLSLTYDV 314
            : ||.|.:::.:::|:... :.:||||..:|.:....|   |.|:.||||:.| ..:|   .::.
  Rat   289 DGEKTFVAQMTVFDKNRRLQLLDGEYEVAMQEMEECPI---SKKRATWETILDGKRLP---PFET 347

  Fly   315 YQQSPMLKFHLTL---SNEQLPEMISAPELQRYVQHLDAVAEMNYNNNNYNNNNNCSGLKNGSGG 376
            :.|.|.|:|.|..   :|::....::.|...|             |:.:.:..|     |.||..
  Rat   348 FSQGPTLQFTLRWTGETNDKSTAPVAKPLATR-------------NSESLHQEN-----KPGSVK 394

  Fly   377 GNSTVC------------------KTTPEHIQIVYNFMYSNNTRQQTEYTQELNCPWCGLDCLRL 423
            ...|:.                  ..|.:.::|.|.|:|:||||||||...:|:||||.|:|.:|
  Rat   395 PAQTIAVKETLTTEMQTRKEKDTSNETRQKLRIFYQFLYNNNTRQQTEARDDLHCPWCTLNCRKL 459

  Fly   424 YALLKHLKLCHAR--FNFTYQPAGSGARIDVTINDAYDGSYAGSPYDLAGPSGSSFARTCGPVRR 486
            |:|||||||||:|  ||:.|.|  .||||||:||:.|||||||:|.|:....|.:|:|. |||:|
  Rat   460 YSLLKHLKLCHSRFIFNYVYHP--KGARIDVSINECYDGSYAGNPQDIHRQPGFAFSRN-GPVKR 521

  Fly   487 TSVTSLMVCRPRRQKTCLDEFLELDEDEISNQRSYITGHNRLYHHTETCLPVHPKELDIDSEGES 551
            |.:|.::||||:|.|..:.||||.::.|:..||:|.:||||||.|::||||:.|:|:::|||.|.
  Rat   522 TPITHILVCRPKRTKASMSEFLESEDGEVEQQRTYSSGHNRLYFHSDTCLPLRPQEMEVDSEDEK 586

  Fly   552 DPLWLRQKTIQMIDEFSDVNEGEKELMKLWNLHVMRHGFVGDCQLPIACEMFLDAKGTEIVRKNL 616
            ||.|||:|||..|:|||||||||||:|||||||||:|||:.|.|:..||.:|::..|.:|::|||
  Rat   587 DPEWLREKTITQIEEFSDVNEGEKEVMKLWNLHVMKHGFIADNQMNHACMLFVENYGQKIIKKNL 651

  Fly   617 YRNFILHMCSLFDYGLIAAETVYKTVQKLQGLLSKYAAGQ 656
            .|||:||:.|:.|:.||:..::.|.|.||:.:..|...|:
  Rat   652 CRNFMLHLVSMHDFNLISIMSIDKAVTKLREMQQKLEKGE 691

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Su(z)12	NP_730465.1	VEFS-Box	511..644	CDD:286776	74/132 (56%)
Suz12	XP_038943572.1	VEFS-Box	545..679	CDD:401612	74/133 (56%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	232	1.000	Domainoid score	I2343
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H32256
Inparanoid	1	1.050	406	1.000	Inparanoid score	I1840
OMA	1	1.010	-	-		QHG49982
OrthoDB	1	1.010	-	-		D122694at33208
OrthoFinder	1	1.000	-	-		FOG0002735
OrthoInspector	1	1.000	-	-		oto96130
orthoMCL	1	0.900	-	-		OOG6_106100
Panther	1	1.100	-	-	LDO	PTHR22597
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2535
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	13	12.980