Protein Alignment Su(z)12 and suz12b

DIOPT Version :9

• Sequence 1: NP_730465.1
• Gene: Su(z)12 / 48071
• FlyBaseID: FBgn0020887
• Length: 900
• Species: Drosophila melanogaster
• Sequence 2: XP_021332565.1
• Gene: suz12b / 561871
• ZFINID: ZDB-GENE-030131-3255
• Length: 685
• Species: Danio rerio
• Alignment Length: 700
• Identity: 255/700 - (36%)
• Similarity: 383/700 - (54%)
• Gaps: 84/700 - (12%)

  Fly     1 MAPAKKREKDSNPDGSAANGIIGLTHGAPDASNAGSTVPPTAEGQVKLNGHQQEQELFLQAFEKP 65
            |||.|...:..|   |.|||.:      ..:|...|...|      |:...|.:.||||||||||
Zfish     1 MAPQKYSAQVMN---SKANGAV------YPSSGVSSLKKP------KIEQLQADHELFLQAFEKP 50

  Fly    66 TQIYRYLRNRHETNPIFLNRTLSYMKERMSRNNKKRISFQVNSMLESITQ-KSEAVS---QNYLH 126
            |||||:||.|:...|:.|:|||::|..|.||.|.||.||:|:.:|.|:.: |.|..|   .::|.
Zfish    51 TQIYRFLRTRNLITPVLLHRTLTFMSHRNSRTNAKRKSFKVDDLLSSVEKMKGEPESPSLTSHLQ 115

  Fly   127 VIYDSLHEKLPARLDNESGEDLLQEQLLCEAGESVSVETTLYKITRSKRKDSTLDFQELLSKCSQ 191
            :.:.....|......|...|.           .|||:|..|.|:...||||.:...:::.:...|
Zfish   116 LTFTGFFHKNVKPCQNSENEQ-----------NSVSLEVLLVKVCHKKRKDVSCPIKQVPTGKKQ 169

  Fly   192 IVYNP---KDRVGEHATISIPLQTMRPMGEQHTL--YKLLFRIKVLSPSTCN-------DENA-- 242
            :..||   :.:.|...::.:......| ...|.:  |.||||:........|       |||.
Zfish   170 VPLNPDLSQTKPGAFPSLLVSSNEFEP-SNSHMVKSYSLLFRVSHTGKRDPNGFISCEADENIDV 233

  Fly   243 --ETPPNKRSRPN-------EKMFGSELILYEKSSGF-ITEGEYEAMLQPLNSTSIKSFSPKKCT 297
              |.||.::...:       .:.|.:::.:::|:... :.:||||..:|.:....:   |.|:.|
Zfish   234 KDEIPPRRKRNSSLRGDGETTETFVAQMTVFDKNRRLQLLDGEYEVSMQQIEDCPV---SKKRAT 295

  Fly   298 WETMPDSYIPLSL-TYDVYQQSPMLKFHLTLSNEQLPEMISAPELQRYVQHLDAVAEMNYNNNNY 361
            |||:.|..:...| .::.:.|.|.|:|.|..:.:.     |.|......:.|.     ..|::..
Zfish   296 WETILDGKVAYRLPPFETFSQGPTLQFTLRWTADP-----SDPSTAPVAKPLS-----TRNSDTS 350

  Fly   362 NNNNNCSGLKNGSGG---GNSTVCKTTPEH--------IQIVYNFMYSNNTRQQTEYTQELNCPW 415
            ...:..|.|:.....   ..||..::..||        ::|.|.|:|:||||||||...:|:|||
Zfish   351 TTESRISTLRPAPVAVKESVSTSMQSRIEHSPCEPRQKLRIFYQFLYNNNTRQQTEARDDLHCPW 415

  Fly   416 CGLDCLRLYALLKHLKLCHARFNFTYQPAGSGARIDVTINDAYDGSYAGSPYDLAGPSGSSFART 480
            |.|:|.:||:|||||||.|:||.|.|.|...||||||:||:.|||||.|:|.|:....|.:|:|.
Zfish   416 CTLNCRKLYSLLKHLKLSHSRFIFNYVPHPKGARIDVSINECYDGSYVGNPQDIHSQPGFAFSRN 480

  Fly   481 CGPVRRTSVTSLMVCRPRRQKTCLDEFLELDEDEISNQRSYITGHNRLYHHTETCLPVHPKELDI 545
             |||:||:||.::||||:|.|..|.||||.::.|...||:|::||||||.|:::|:|:.|:|:::
Zfish   481 -GPVKRTAVTHILVCRPKRTKPSLSEFLESEDGEPEQQRTYVSGHNRLYFHSDSCMPLRPQEMEV 544

  Fly   546 DSEGESDPLWLRQKTIQMIDEFSDVNEGEKELMKLWNLHVMRHGFVGDCQLPIACEMFLDAKGTE 610
            |||.|.||.||::||...|:||:||||||||:|||||||||::||:.|.|:..|..:|::..|..
Zfish   545 DSEDERDPEWLQEKTTTQIEEFTDVNEGEKEVMKLWNLHVMKNGFIADNQMSQASMLFVEICGPH 609

  Fly   611 IVRKNLYRNFILHMCSLFDYGLIAAETVYKTVQKLQGLLSKY---AAGQE 657
            |:|:||.|||:||:.:|.|:.|:...|:.:.:.:|:.:...:   .||||
Zfish   610 IIRRNLCRNFLLHLVNLHDFNLVTIATIDQAMARLKEIEESFPELEAGQE 659

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Su(z)12	NP_730465.1	VEFS-Box	511..644	CDD:286776	65/132 (49%)
suz12b	XP_021332565.1	VEFS-Box	509..643	CDD:313029	65/133 (49%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170590151
Domainoid	1	1.000	275	1.000	Domainoid score	I1721
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H32256
Inparanoid	1	1.050	432	1.000	Inparanoid score	I1682
OMA	1	1.010	-	-		QHG49982
OrthoDB	1	1.010	-	-		D122694at33208
OrthoFinder	1	1.000	-	-		FOG0002735
OrthoInspector	1	1.000	-	-		otm25913
orthoMCL	1	0.900	-	-		OOG6_106100
Panther	1	1.100	-	-	LDO	PTHR22597
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4776
SonicParanoid	1	1.000	-	-		X2535
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	14	13.940