DRSC/TRiP Functional Genomics Resources

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Protein Alignment rin and BRE5

DIOPT Version :10

Sequence 1:NP_524907.2 Gene:rin / 47998 FlyBaseID:FBgn0015778 Length:690 Species:Drosophila melanogaster
Sequence 2:NP_014449.1 Gene:BRE5 / 855787 SGDID:S000005334 Length:515 Species:Saccharomyces cerevisiae


Alignment Length:503 Identity:98/503 - (19%)
Similarity:185/503 - (36%) Gaps:114/503 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly    14 QSVGREFVRQYYTLLNKAPNHLHRFYNHNSSYIHG--ESK------------LVVGQREIHNRIQ 64
            |.:...|::.||..:...|:.|..||...:...|.  :||            .|.|:..|:....
Yeast     6 QDICFAFLQNYYERMRTDPSKLAYFYASTAELTHTNYQSKSTNEKDDVLPTVKVTGRENINKFFS 70

  Fly    65 QLNFNDCHA-----KISQVDAQAT--LGNGVVVQVTGELSNDGQPMRRFTQTFVLAAQS-PKKYY 121
            :   ||...     |:..:|.|.|  |...:::..|||:...|.|:.:|.|||:|...| ...:.
Yeast    71 R---NDAKVRSLKLKLDTIDFQYTGHLHKSILIMATGEMFWTGTPVYKFCQTFILLPSSNGSTFD 132

  Fly   122 VHNDIFR-----YQDLYIEDEQDGESRSENDEEHDVQVVGGTVDQAVQVAGDVVAQQPQQQQAPP 181
            :.|||.|     ::...:.|    .|.|:::||:.|..|  ..|:....:|  |.::.:::::| 
Yeast   133 ITNDIIRFISNSFKPYVLTD----ASLSQSNEENSVSAV--EEDKIRHESG--VEKEKEKEKSP- 188

  Fly   182 QPQAQVVVPQQVAPVAAGGAAPQQIFYPLPAGAAAGRPVAVLPPAPQAAAVPLPAQF-----TVP 241
                ::..|:..........||.:       .:...:|:.   ...|..|:|:..:.     |||
Yeast   189 ----EISKPKAKKETVKDTTAPTE-------SSTQEKPIV---DHSQPRAIPVTKESKIHTETVP 239

  Fly   242 PPQP--IQNGVVSHEEL-----------QQQQVLVP--------PSVSPLVQQQQPTGTPVLPIV 285
            ....  .:...||.|||           :.::...|        .:::.:.....|.|..|....
Yeast   240 SSTKGNHKQDEVSTEELGNVTKLNEKSHKAEKKAAPIKTKEGSVEAINAVNNSSLPNGKEVSDEK 304

  Fly   286 PVPSAGFQQSPL----VAPQLIQQQQQQQPAQLPPQQQQQQQPIQQQQPLQQQQQPLAEPEEV-- 344
            ||| .|.:::..    :.||:...::....|..|                ....:|:|.|.::  
Yeast   305 PVP-GGVKEAETEIKPIEPQVSDAKESGNNASTP----------------SSSPEPVANPPKMTW 352

  Fly   345 ------EVAPRQQKPPTPVEDFK--TIHEQQQQEKYEAAKQQQNEPKTYANLFKSTSS--SPSGF 399
                  |.:.|..|..|.||..:  |:.::..:.|:|...::.|......|..|...|  :..||
Yeast   353 ASKLMNENSDRISKNNTTVEYIRPETLPKKPTERKFEMGNRRDNASANSKNKKKPVFSTVNKDGF 417

  Fly   400 VNAALQQQQQLQQQQQQQQSISSNTYNSSSATSGGGNGSQVSYSTTAS 447
            ....::....|  ::::.:|.....:......:...|.:.|.:.|..|
Yeast   418 YPIYIRGTNGL--REEKLRSALEKEFGKVMRITAADNFAVVDFETQKS 463

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
rinNP_524907.2 NTF2 12..131 CDD:238403 36/143 (25%)
RRM_G3BP 490..580 CDD:409676
BRE5NP_014449.1 NTF2 4..142 CDD:238403 36/138 (26%)
RRM_SF 427..483 CDD:473069 6/39 (15%)
Blue background indicates that the domain is not in the aligned region.

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