Protein Alignment rin and g3bp2a

DIOPT Version :9

• Sequence 1: NP_524907.2
• Gene: rin / 47998
• FlyBaseID: FBgn0015778
• Length: 690
• Species: Drosophila melanogaster
• Sequence 2: NP_001074032.1
• Gene: g3bp2a / 556409
• ZFINID: ZDB-GENE-070112-1972
• Length: 507
• Species: Danio rerio
• Alignment Length: 713
• Identity: 214/713 - (30%)
• Similarity: 298/713 - (41%)
• Gaps: 236/713 - (33%)

  Fly     1 MVMDATQSQQPSPQSVGREFVRQYYTLLNKAPNHLHRFYNHNSSYIHGE-------SKLVVGQRE 58
            |||     ::|||..|||||||||||||||||:.|||||..||||:||.       |:.|.||.|
Zfish     1 MVM-----EKPSPLLVGREFVRQYYTLLNKAPDFLHRFYGRNSSYVHGGLDLNGKLSEAVYGQAE 60

  Fly    59 IHNRIQQLNFNDCHAKISQVDAQATLGNGVVVQVTGELSNDGQPMRRFTQTFVLAAQS--PKKYY 121
            ||.::..|.|::||.||..|||.|||.:||||||.|||||:|||||:|.||||||.:.  ..|:|
Zfish    61 IHKKVMSLQFSECHTKIRHVDAHATLSDGVVVQVMGELSNNGQPMRKFLQTFVLAPEGSVANKFY 125

  Fly   122 VHNDIFRYQDLYIEDEQDGESRSENDEEHDVQVVGGTVDQAVQVAGDVVAQQPQQQQAPPQPQAQ 186
            ||||||||     |||..|:|.:|.|||.:.:                 ..:|:.:|..|:
Zfish   126 VHNDIFRY-----EDEVFGDSEAELDEESEEE-----------------TDEPEDRQPSPE---- 164

  Fly   187 VVVPQQVAPVAAGGAAPQQIFYPLPAGAAAGRPVAVLPPAPQAAAVPLPAQFTVPPPQPIQNGVV 251
               |.|.:|..|      ..:.|.|.....|     :..|.:.|.:.|  |..|.|...|:...:
Zfish   165 ---PLQDSPSNA------NCYEPHPVSCNNG-----VEEAHEEAVMDL--QSEVAPDPKIEESKL 213

  Fly   252 SHEELQ----QQQVLVP-PSVSPLVQQQQP-------TGTPVLPIV-PVPSAGFQQSPLVAPQLI 303
            ..||..    :::.|.| |..||...|:.|       ..:..||:. .|||||.|...:.||. .
Zfish   214 KVEEKDVEEFEEKALSPVPLESPPNIQEPPKTSSWASVTSKNLPLSGTVPSAGGQPHVVKAPN-T 277

  Fly   304 QQQQQQQPAQLPPQQQQQQQPIQQQQPLQQQQQPLAEPEEVEVAPRQQKPPTPVEDFKTIHEQQQ 368
            |.:.:.:|..|....:.:.|.|:.:.|:..:            .||....|:
Zfish   278 QPRVETKPEMLSASIRPRDQRIRDRPPVTSR------------GPRSDGVPS------------- 317

  Fly   369 QEKYEAAKQQQNEPKTYANLFKSTSSSPSGFVNAALQQQQQLQQQQQQQQSISSNTYNSSSATSG 433
                       :||:.....|        .|||.
Zfish   318 -----------SEPQAGKPHF--------SFVNK------------------------------- 332

  Fly   434 GGNGSQVSYSTTASSYNNSNGNSRLDNGGPLPQRNNSIRNNKGDFEQRRSSNTQQFGDNQQLFLG 498
                            ..::.:|.:|                       |....::.|:.|||:|
Zfish   333 ----------------GRADESSEMD-----------------------SRRVVRYPDSHQLFVG 358

  Fly   499 NIPHHASEDDLREIFSRFGNVLELRILSKA-GNKVPPGMRSPLNYGFITYDDPEAVQKCLANCPL 562
            |:||...|.:|::.|..||||:||||.:|: |.|:|       |:||:.:||.|.||:.|...|:
Zfish   359 NLPHDIDESELKDFFMTFGNVVELRINTKSTGGKIP-------NFGFVVFDDSEPVQRILGVKPI 416

  Fly   563 YFPENSPDGQ-KLNVEEKKPRVRNDMVPRQQIGGNNLNNNMGRLGGNNGPQSRPMGNNNGSGGGM 626
            .|     .|: :|||||||.|...:...|..:|.:  ..::.|             ::.|.||
Zfish   417 MF-----RGEVRLNVEEKKTRAMRERETRSGVGDD--RRDVRR-------------SDRGPGG-- 459

  Fly   627 MRNNAGGNNLRQGGGGGNGAPRLGGGGGFGQRQDNRTGGGNNQSNGPLRGAGNGQSGGGNYGR 689
            .|..||||.:|:  ..|.|.|                   :..:..|..|..:|:..|.|.||
Zfish   460 PRGIAGGNMMRE--RDGRGPP-------------------SRVATVPKPGLASGRGSGSNEGR 501

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rin	NP_524907.2	NTF2	12..131	CDD:238403	82/127 (65%)
		RRM	423..>557	CDD:223796	34/134 (25%)
		RRM_G3BP	490..580	CDD:240675	40/91 (44%)
g3bp2a	NP_001074032.1	NTF2	7..135	CDD:238403	82/132 (62%)
		RRM_SF	348..430	CDD:327398	40/93 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170595205
Domainoid	1	1.000	162	1.000	Domainoid score	I3950
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53615
OrthoDB	1	1.010	-	-		D1526879at2759
OrthoFinder	1	1.000	-	-		FOG0000749
OrthoInspector	1	1.000	-	-		otm24901
orthoMCL	1	0.900	-	-		OOG6_102794
Panther	1	1.100	-	-	O	PTHR10693
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X634
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	12	11.860