Protein Alignment rin and g3bp2b

DIOPT Version :9

• Sequence 1: NP_524907.2
• Gene: rin / 47998
• FlyBaseID: FBgn0015778
• Length: 690
• Species: Drosophila melanogaster
• Sequence 2: XP_021325450.1
• Gene: g3bp2b / 406683
• ZFINID: ZDB-GENE-040426-2698
• Length: 501
• Species: Danio rerio
• Alignment Length: 716
• Identity: 218/716 - (30%)
• Similarity: 298/716 - (41%)
• Gaps: 250/716 - (34%)

  Fly     1 MVMDATQSQQPSPQSVGREFVRQYYTLLNKAPNHLHRFYNHNSSYIHG-------ESKLVVGQRE 58
            |||     ::|||..|||||||||||||||||::|||||..||||:||       ..:.|.||.|
Zfish     1 MVM-----EKPSPLLVGREFVRQYYTLLNKAPDYLHRFYGRNSSYVHGGLDSNGKPEEAVYGQAE 60

  Fly    59 IHNRIQQLNFNDCHAKISQVDAQATLGNGVVVQVTGELSNDGQPMRRFTQTFVLAAQ--SPKKYY 121
            ||.::..|.|::||.||..|||.||||:||||||.|||||.|:|||||.||||||.:  :..|:|
Zfish    61 IHKKVMSLQFSECHTKIRHVDAHATLGDGVVVQVMGELSNSGRPMRRFMQTFVLAPEGSAVNKFY 125

  Fly   122 VHNDIFRYQDLYIEDEQDGESRSE--NDEEHDVQVVGGTVDQAVQVAGDVVAQQPQQQQAPPQPQ 184
            ||||||||     |:|..|:|.:|  ..||.:|:                  ::|.:..|.|:|
Zfish   126 VHNDIFRY-----EEEVFGDSEAELGESEEEEVE------------------EEPVETHASPEP- 166

  Fly   185 AQVVVPQQVAPVAAGGAAPQQIFYPLPAGAAAGRPVAVLPPAPQAAAVPLPAQFTVPPPQPIQNG 249
                                          |..||.:              ..:..||| |:.||
Zfish   167 ------------------------------AQDRPSS--------------TTYYEPPP-PVSNG 186

  Fly   250 VVSHEELQQQQVLVPPSVSPLVQQQQPTGTPVLPIVPVPSAGFQQSPLVAPQLIQQQQQQQPAQL 314
            |   ||.|::.|   |.|.|.|:
Zfish   187 V---EEQQEEAV---PEVEPEVE------------------------------------------ 203

  Fly   315 PPQQQQQQQPIQQQQPLQQQQQPLAEPEEVEVAPRQQKPPTPVEDFKTIHEQQQQEKYEAAKQQQ 379
             |:....|:|..:.....:.|...|||||.|..|.:::..||            ........|..
Zfish   204 -PEALASQEPEAELSTEAELQVAEAEPEEEEKLPEEERGSTP------------GLALTPPPQTP 255

  Fly   380 NEPKTYA-NLFKSTSSSPSGFVNA---------ALQQQQQLQQQQQQQQSISSNT------YNSS 428
            ..||.:: .|..|.:..|:|.:.|         |...|.:::.:|....|:|.:.      :...
Zfish   256 EPPKAFSWALVTSKNLPPAGALPASGISPHVVKASSVQPRVELKQDGPSSLSRDQRRERPGFTPR 320

  Fly   429 SATSGGGNGSQVSYSTTASSYNNSNGNSRLDNGGPLPQRNNSIRNNKGDFEQRRSSNTQQFGDNQ 493
            .|.:.|| ||:.|                  .|.|..........:.||.|.|||.   ::.|:.
Zfish   321 GARADGG-GSEAS------------------GGKPYISFKGRGDGDAGDTEGRRSF---RYPDSH 363

  Fly   494 QLFLGNIPHHASEDDLREIFSRFGNVLELRILSK-AGNKVPPGMRSPLNYGFITYDDPEAVQKCL 557
            |||:||:||...|.:|::.|..||||:|:||.:| .|.|:|       |:||:.:||.:.||:.|
Zfish   364 QLFVGNLPHDIDEGELKDFFMTFGNVVEMRINTKGVGGKLP-------NFGFVVFDDSDPVQRIL 421

  Fly   558 ANCPLYFPENSPDGQ-KLNVEEKKPRVRNDMVPRQQIGGNNLNNNMGRLGGNNGPQSRPMGNNNG 621
            ...|:.|     .|: :|||||||.|...:
Zfish   422 GAKPIMF-----RGEVRLNVEEKKTRAVRE----------------------------------- 446

  Fly   622 SGGGMMRNNAGGNNLRQGGGGGNGAPRLGGGGGFGQRQDNRTGGGNNQSNGPLRGAGNGQSGGGN 686
                  |...|..:.|:|       ||...|.|.|:.:|:|   |...|.|.: |||.||||...
Zfish   447 ------RETRGPPDARRG-------PRGIMGNGMGRERDSR---GPPASRGGM-GAGRGQSGESR 494

  Fly   687 Y 687
            :
Zfish   495 F 495

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rin	NP_524907.2	NTF2	12..131	CDD:238403	82/127 (65%)
		RRM	423..>557	CDD:223796	43/140 (31%)
		RRM_G3BP	490..580	CDD:240675	38/91 (42%)
g3bp2b	XP_021325450.1	NTF2	7..135	CDD:238403	82/132 (62%)
		RRM_G3BP2	358..440	CDD:240910	38/93 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170595203
Domainoid	1	1.000	162	1.000	Domainoid score	I3950
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53615
OrthoDB	1	1.010	-	-		D1526879at2759
OrthoFinder	1	1.000	-	-		FOG0000749
OrthoInspector	1	1.000	-	-		otm24901
orthoMCL	1	0.900	-	-		OOG6_102794
Panther	1	1.100	-	-	O	PTHR10693
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X634
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	12	11.860