Protein Alignment rin and g3bp2

DIOPT Version :10

• Sequence 1: NP_524907.2
• Gene: rin / 47998
• FlyBaseID: FBgn0015778
• Length: 690
• Species: Drosophila melanogaster
• Sequence 2: NP_989273.1
• Gene: g3bp2 / 394887
• XenbaseID: XB-GENE-480361
• Length: 484
• Species: Xenopus tropicalis
• Alignment Length: 698
• Identity: 205/698 - (29%)
• Similarity: 289/698 - (41%)
• Gaps: 253/698 - (36%)

  Fly     1 MVMDATQSQQPSPQSVGREFVRQYYTLLNKAPNHLHRFYNHNSSYIHG-------ESKLVVGQRE 58
            |||     ::|||..|||||||||||||||||:.|||||..||||:||       ..:.|.||.|
 Frog     1 MVM-----EKPSPLLVGREFVRQYYTLLNKAPDFLHRFYGRNSSYVHGGLDATGKPQEAVYGQAE 60

  Fly    59 IHNRIQQLNFNDCHAKISQVDAQATLGNGVVVQVTGELSNDGQPMRRFTQTFVLAAQS--PKKYY 121
            ||.::..|.|::|..||..|||.|||.:||||||.|||||:|||||:|.||||||.:.  |.|:|
 Frog    61 IHKKVMSLQFSECRTKIRHVDAHATLSDGVVVQVMGELSNNGQPMRKFMQTFVLAPEGSVPNKFY 125

  Fly   122 VHNDIFRYQDLYIEDEQDGESRSENDEEHDVQVVGGTVDQAVQVAGDVVAQQPQQQQAPPQPQAQ 186
            ||||||||     |||..|:|.:|.|||.:.:|                  :.:|::..|.|:
 Frog   126 VHNDIFRY-----EDEVFGDSEAEMDEESEEEV------------------EEEQEERQPSPE-- 165

  Fly   187 VVVPQQVAPVAAGGAAPQQIFYPLPAGAAAGRPVAVLPPAPQAAAVPLPAQFTVPPPQPIQNGVV 251
                                    ||......  |...|.|.:..|..|.:..|..|:|.....:
 Frog   166 ------------------------PAQENTNN--AYYEPHPVSNGVEEPLEEPVNEPEPEPEPEI 204

  Fly   252 SHEELQ-----------QQQVLVPPSVSPLVQQQQP---------TGTPVLPIVPVPSAGFQQSP 296
            .:||::           :::...||...|:|..|:|         |...:.|...||::|
 Frog   205 KNEEIKPETEEKVQEELEEKSPTPPPAEPVVLPQEPPKAFSWASVTSKNLPPSGTVPASG----- 264

  Fly   297 LVAPQLIQQQQQQQPAQLPPQQQQQQQPIQQQQPLQQQQQPLAEPEEVEVAPRQQKPPTPVEDFK 361
             :.|.:|:....|....:.|:...|...:::|:|   :::|..:|.    .||.
 Frog   265 -IPPHVIKAPASQARVDVKPEAPAQSLRVREQRP---RERPAFQPR----GPRV----------- 310

  Fly   362 TIHEQQQQEKYEAAKQQQNEPKTYANLFKSTSSSPSGFVNAALQQQQQLQQQQQQQQSISSNTYN 426
                                                                             
 Frog   311 ----------------------------------------------------------------- 310

  Fly   427 SSSATSGGGNGSQVSYSTTASSYNNSNGNSRLDNGGPLPQRNNSIRNNKGDFEQRRSSNTQ--QF 489
                   ||                     |.||                  ||..|.|.:  ::
 Frog   311 -------GG---------------------RSDN------------------EQSESDNRRMYRY 329

  Fly   490 GDNQQLFLGNIPHHASEDDLREIFSRFGNVLELRILSK-AGNKVPPGMRSPLNYGFITYDDPEAV 553
            .|:.|||:||:||...|.:|:|.|..:|||:||||.:| .|.|:|       |:||:.:||.|.|
 Frog   330 PDSHQLFVGNLPHDIDESELKEFFMSYGNVMELRINTKGVGGKLP-------NFGFVVFDDSEPV 387

  Fly   554 QKCLANCPLYFPENSPDGQ-KLNVEEKKPRVRNDMVPRQQIGGNNLNNNMGRLGGNNGPQSRPMG 617
            |:.|.:.|:.|     .|: :|||||||.|...:   |:..||::..:......|..||:..
 Frog   388 QRILLSKPIMF-----RGEVRLNVEEKKTRAARE---RETRGGDDRRDIRRNDRGPGGPRGL--- 441

  Fly   618 NNNGSGGGMMRNNAG------GNNLRQGGGGGNGAPRLGGGGGFGQRQ 659
                ..|||:|:..|      |..:::.|.|..|||.:.|... |||:
 Frog   442 ----ISGGMVRDRDGRGPPPRGGMVQKLGSGRGGAPPVEGRFS-GQRR 484

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rin	NP_524907.2	NTF2	12..131	CDD:238403	81/127 (64%)
		RRM_G3BP	490..580	CDD:409676	40/91 (44%)
g3bp2	NP_989273.1	NTF2	7..135	CDD:238403	81/132 (61%)
		PRK12323	<210..>326	CDD:481241	31/250 (12%)
		RRM_G3BP2	328..410	CDD:409897	40/93 (43%)