Protein Alignment rin and gtbp-1

DIOPT Version :9

• Sequence 1: NP_524907.2
• Gene: rin / 47998
• FlyBaseID: FBgn0015778
• Length: 690
• Species: Drosophila melanogaster
• Sequence 2: NP_501842.2
• Gene: gtbp-1 / 177880
• WormBaseID: WBGene00010677
• Length: 473
• Species: Caenorhabditis elegans
• Alignment Length: 692
• Identity: 139/692 - (20%)
• Similarity: 227/692 - (32%)
• Gaps: 270/692 - (39%)

  Fly     3 MDATQSQQP----SPQSVGREFVRQYYTLLNKAPNHLHRFYNHNSSYIHGESKLVVGQREI---H 60
            :.:|...:|    :.:.||..|..|:|..:::....:.:||.|.|.: :.:.::|.|.:||   :
 Worm    19 LTSTAPVEPLSLTAAEQVGGAFCHQFYITVSENRKAITKFYGHESKF-YLDDQVVTGSQEIVKLY 82

  Fly    61 NRIQQLNFNDCHAKISQVDAQAT-LGNGVVVQVTGELSNDGQPMRRFTQTFVLAAQSPKKYYVHN 124
            |.:.:..    |.||..:....| ...||::.|.|.::     :|.|.|:|:|..|..|||||.:
 Worm    83 NHLPETT----HFKIQSIKGYPTPHKQGVIINVIGTVN-----LRPFLQSFLLGQQGQKKYYVES 138

  Fly   125 DIFRYQD-LYIEDEQDGESRSENDEEHDVQVVGGTVDQAVQVAGDVVAQQPQQQQAPPQPQAQVV 188
            |.|:|.| .::.:.:..::.|............|...::.:      .:||::|..|..|:.|
 Worm   139 DAFQYIDKFFVANTEKEKTTSSTGHNGHASGANGKDSKSSK------TEQPKEQSKPAPPKQQ-- 195

  Fly   189 VPQQVAPVAAGGAAPQQIFYPLPAGAAAGRPVAVLPPAPQAAAVPLPAQFTVPPPQPIQNGVVSH 253
            .|::..........|:.:          .:.||..|..||.|..| |.| ..|.|:|:|.
 Worm   196 TPKKAEDRIVKQDTPKSV----------EKEVAKTPQKPQLAQQP-PQQ-RAPVPEPVQE----- 243

  Fly   254 EELQQQQVLVPPSVSPLVQQQQPTGTPVLPIVPVPSAGFQQSPLVAPQLIQQQQQQQPAQLPPQQ 318
                          .|.||:....        .|...|..|                    ||||
 Worm   244 --------------QPKVQKTWAN--------LVGGGGKSQ--------------------PPQQ 266

  Fly   319 QQ--QQQPIQQQQPLQQQQQPLAEPEEVEVAPRQQKPPTPVEDFKTIHEQQQQEKYEAAKQQQNE 381
            |.  |.|.|.||..:...|                         .::|:|||
 Worm   267 QSYGQGQQIHQQTQMHHMQ-------------------------PSMHQQQQ------------- 293

  Fly   382 PKTYANLFKSTSSSPSGFVNAALQQQQQLQQQQQQQQSISSNTYNSSSATSGGGNGSQVSYSTTA 446
             .::|.|:                        |||:||..:|....:..:|
 Worm   294 -GSHAPLY------------------------QQQRQSHPANELRQAQESS-------------- 319

  Fly   447 SSYNNSNGNSRLDNGGPLPQRNNSIRNNKGDFEQRRSSNTQQFGDNQQLFLGNIPHH-------A 504
                ::|.|.|                                    :::||.|...       .
 Worm   320 ----DANLNER------------------------------------KIYLGGITREIVPSNTAQ 344

  Fly   505 SEDDLREIFSRFGNVLELRILSKAGNKVPPGMRSPLNYGFITY--------------DDPEAVQK 555
            :|.:::::|.::|.:.|:|:..|..:.  |...|...:.|||.              .|.:.|.|
 Worm   345 AESEIKQVFYKYGEIEEVRMPRKVLDS--PNDTSKHAFAFITMRNKAGVKAIFEAATKDEQGVWK 407

  Fly   556 CLANCPLYFPENSPDGQ-KLNVEEKKPRVRNDMVPRQQIGGNNLNNNMGRLGGNNGPQSRPMGNN 619
                .||.......||. :::.:..:|:           ||       |..||..|.|.|
 Worm   408 ----LPLKLDAFGFDGHAQISEQRDQPQ-----------GG-------GFRGGRGGFQPR----- 445

  Fly   620 NGSGGGMMRNNAGGNNLRQGGGGGNGAPRLGGGGGFGQRQDN 661
                        ||...|:||.|  ||||.|...||.....|
 Worm   446 ------------GGQFFRRGGSG--GAPRGGMRSGFQNAGQN 473

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rin	NP_524907.2	NTF2	12..131	CDD:238403	36/122 (30%)
		RRM	423..>557	CDD:223796	22/154 (14%)
		RRM_G3BP	490..580	CDD:240675	21/111 (19%)
gtbp-1	NP_501842.2	NTF2	33..145	CDD:238403	36/121 (30%)
		RRM_SF	326..404	CDD:302621	16/115 (14%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160166720
Domainoid	1	1.000	57	1.000	Domainoid score	I7311
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S3606
OMA	1	1.010	-	-		QHG53615
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_102794
Panther	1	1.100	-	-	LDO	PTHR10693
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R463
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.830