Protein Alignment scat and VPS54

DIOPT Version :10

• Sequence 1: NP_524905.1
• Gene: scat / 47942
• FlyBaseID: FBgn0011232
• Length: 940
• Species: Drosophila melanogaster
• Sequence 2: NP_010310.1
• Gene: VPS54 / 851591
• SGDID: S000002434
• Length: 889
• Species: Saccharomyces cerevisiae
• Alignment Length: 869
• Identity: 167/869 - (19%)
• Similarity: 301/869 - (34%)
• Gaps: 253/869 - (29%)

  Fly   107 YHVNQHTREMPPEWGVYSAAQNLPAVLNDPSRGKQSNLFTKKWGEHFVERSHVPPSPRLPDITHA 171
            |.:..:||.  ..|      .|.|.|.:.|......|.....|..|.:|
Yeast   114 YEIVMNTRR--KNW------LNYPTVADIPQVSLSKNDLDDHWKTHVIE---------------- 154

  Fly   172 DFTVYLGSIGKRYRWHE-----RRQQQLERDKPLENG------------AQGAPGPGTGGQTPTH 219
                |:.:|...|:..:     |...|:|:.|.|..|            .||         ....
Yeast   155 ----YVKNIKSDYQIFQSTNNIRNMNQMEQLKELREGENMHEESFEANLRQG---------DAEL 206

  Fly   220 LSSVPEIFLKSQLQLHHPATFKQVFPNY--------MQTSASSPESHQQTGRQLQEQLSHYLDMV 276
            ::|:|:.:...:.||.:|.||.:|....        |:..|...|:..    :|:::|:.:||:|
Yeast   207 INSIPDFYFSDKFQLDNPRTFHKVLDAIDLFLTKLDMKRQAERDEAFS----ELRDRLNDFLDIV 267

  Fly   277 EVKIAQQVSQKSAAFFHAMTTQHAI-------LAEMEQAADQVR-----QLRAALAELHSHSVVD 329
            |..:..::|:.|..||||::....|       ::|:::.|..::     .:|..::  |...:..
Yeast   268 ETLLVTEISKSSHKFFHALSEVDNIQKRALDTMSELKELAQNIKTIDAENIRKKIS--HLEMIFK 330

  Fly   330 SFKVLRFAQRRQHYNLTL---DKLRLMATVHKTQPMLQLLLGTQDYVAALDLIGTTQEILSAELL 391
            ...|.:..|......|.|   |:.:.|...:|....|:|:......:...|.|  .:::.|
Yeast   331 RKNVEKLEQGLLQAKLVLNKTDECKSMYEENKLDNCLELIKSIDYLIKGDDSI--NEDVQS---- 389

  Fly   392 GIHCFKHLPMQLSEMEKLIDKMLTTEFERYA--------AADLNRPLTDALRETDSVCAE----- 443
            ...|:   |.:||.:..:.....|.||....        :..|:..|.|.||   |.|..
Yeast   390 WTRCW---PYKLSNLRTIPALSATREFLTNMKIEIGGKFSLQLSILLIDDLR---SFCKSIKPKE 448

  Fly   444 ---------------------EDKLVAIVMGLLRKQNF-SFVQAYQQEAIATIRAIIKQLLIEVL 486
                                 ..|:..:::.|.|.:.. |....|::::|..:::|||..|....
Yeast   449 TLHRIQTGSNDKKQTIFTDNFSSKITELIVRLNRCEELTSAFDLYREKSITELKSIIKIYLPTEN 513

  Fly   487 ARSDSDQEISLTGHGEQA--------LELTLPEWIALLQRSSQALVSI----LERIKTVVGIMQQ 539
            |.:|::.:.....:|..:        .|.|..|:.::       ||:|    ||.::.:.|..:.
Yeast   514 AHADNNHDEKHLNNGSTSGSKLSRLIKEQTPAEFQSM-------LVNIFTHALEALRRLYGHQKL 571

  Fly   540 TADAAVGAQDAVNLIDSEAFLSPGHHEQLKNQLQQL-----LQAVCHYCHERCANIVSPQSLERS 599
            ..|        ::|.:..:..||  :|...|.:.||     :..:......|...|:
Yeast   572 LLD--------ISLNELASVKSP--NENQHNMITQLDIRTGINEIIRIIQLRTGKII-------- 618

  Fly   600 SASEQELFQLSEIVDHF------------------GE-TTRSICGVASVPLQLALKVQASRYAQR 645
             |..:|| .||...|:|                  || .|:.:..|        |..|...||..
Yeast   619 -AVRREL-NLSLRYDYFLKFYAICVIFIQECEVLSGEFLTKYLSNV--------LASQIKHYANA 673

  Fly   646 FHSERKQKLSLLLDQERW-----------------RQVDI-PHEFQRIIERMAAG---------- 682
            ..|:..:.:...:|.|.|                 ..:|| |..:..|:: |..|
Yeast   674 QSSKNYRNIKKKIDAEEWIPYIVDSSIQSDVNDIVSSIDIDPLSWTTILD-MVGGSHDCENGRSE 737

  Fly   683 DYAKPEMGNLISNGAGNPVLLVEGKQPYTLVSASLMLIRMLYEYGCSAHRLP-LLASYHARNVVD 746
            |..|.| ||....|....|  |.|.:.:...|:.|..|.::.|....:..|| :..|...:...|
Yeast   738 DKEKDE-GNETYQGHRKSV--VVGDKTFVASSSLLATIEVIKELMVLSINLPSIYLSNFEKLCYD 799

  Fly   747 LLRCFNSRSCQLIIGAGAMRVAGLKTITSTNLALVSRALQLVLWLLPKLKEHFQAMSGYETIERD 811
            .|:.:||.:...:...|...:.     |..||:::..:|..:...:..::..:|.:|   ...||
Yeast   800 ALQYYNSSAMASVTQPGNSLLK-----TGRNLSIMGESLDCLAEFVIIVQRFYQRLS---NSNRD 856

  Fly   812 YQ-----------GHIKEIENKIH 824
            ::           |..:...|||:
Yeast   857 FEPFDASHYTTLLGQFQASSNKIY 880

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
scat	NP_524905.1	COG2	268..>418	CDD:473160	33/164 (20%)
		Vps54	708..829	CDD:462318	24/129 (19%)
		DUF4164	<810..867	CDD:433450	6/26 (23%)
VPS54	NP_010310.1	None