Protein Alignment scat and Vps54

DIOPT Version :10

• Sequence 1: NP_524905.1
• Gene: scat / 47942
• FlyBaseID: FBgn0011232
• Length: 940
• Species: Drosophila melanogaster
• Sequence 2: NP_620692.3
• Gene: Vps54 / 245944
• MGIID: 2178798
• Length: 977
• Species: Mus musculus
• Alignment Length: 1008
• Identity: 349/1008 - (34%)
• Similarity: 513/1008 - (50%)
• Gaps: 178/1008 - (17%)

  Fly    55 FKSISDFVNHLRNRHCTREGGSFVCRYGFNGVCASLPLDGVSDRDYDAH---VAKYHV-NQHTRE 115
            ||...|...|:|......:            ||...|..       |:|   ||...| :||
Mouse    20 FKKEVDPTKHIRPVQSLPD------------VCPKEPTG-------DSHTLCVAPSLVTDQH--- 62

  Fly   116 MPPEWGVYSAAQNLPAVLNDPSRGK-QSNLFTKKWGEHFVERSHVPPSPRLPDITHADFTVYLGS 179
               .|.||.:..||||.||||:..| :|:.|||.||..||: :.|.||..||.|:..:|..|...
Mouse    63 ---RWTVYHSKVNLPAALNDPTLAKRESDFFTKTWGLDFVD-TEVIPSLYLPQISKENFIAYQQE 123

  Fly   180 IGKRYRWHERRQQQLERDKPLENGAQGAPGPGTGGQTPTH--------LSSVPEIFLKSQLQLHH 236
            |.:|.:.|||.:..             .|...|..:|..|        |..||:||:|....|..
Mouse   124 ISQREKIHERCKNI-------------CPPKDTFDRTLLHIHDKSRTDLEQVPKIFMKPDFALDD 175

  Fly   237 PATFKQVFP-NYMQTSASSPESHQQTGRQLQEQLSHYLDMVEVKIAQQVSQKSAAFFHAMTTQHA 300
            ..||..|.| ::..|:.........:.:.|||:||||||:|||.||.|:|.:|.|||||||:||.
Mouse   176 SLTFNSVLPWSHFNTAGGKGSRDAASSKLLQEKLSHYLDIVEVNIAHQISLRSEAFFHAMTSQHE 240

  Fly   301 ILAEMEQAADQVRQLRAALAELHSHSVVDSFKVLRFAQRRQHYNLTLDKLRLMATVHKTQPMLQL 365
            :...:::....|:.||..:|::.......|.::||.|..|.:.....:||:||||||:|||.:|:
Mouse   241 LQDYLKKTTQAVKMLRDKIAQIDKVMCEGSLQILRLALTRNNCVKVYNKLKLMATVHQTQPTVQV 305

  Fly   366 LLGTQDYVAALDLIGTTQEILSAELLGIHCFKHLPMQLSEMEKLIDKMLTTEFERYAAADLNRPL 430
            ||.|.::|.|||||.||||:|..||.|||.|:||..||.|:|||||||:..||..|:.:||||||
Mouse   306 LLSTSEFVGALDLIATTQEVLQQELQGIHSFRHLGSQLCELEKLIDKMMIAEFSTYSHSDLNRPL 370

  Fly   431 TDALRETDSVCAEEDKLVAIVMGLLRKQNFSFVQAYQQEAIATIRAIIKQLLIEVLAR---SDSD 492
                 |.:....||::||::|.|||:::..:|::.|.:|.|.|.:.|||:.:|..:::   .|:|
Mouse   371 -----EGECQVLEEERLVSLVFGLLKQRKLNFLEIYGEEMIITAKNIIKERVINKVSQIEEIDTD 430

  Fly   493 QEISLTGHGEQALELTLPEWIALLQRSSQALVSILERIKTVVGIM-----------QQT------ 540
            ..:.|   .:|...|..|:||.||:.........|:|:|..:.|:           |:|
Mouse   431 VVVKL---ADQMRMLNFPQWIDLLKDIFSKFTVFLQRVKATLNIIHSVVLSVLEKSQRTRELEEI 492

  Fly   541 -----------------------------------ADAAVG--------------AQDAVN---- 552
                                               |.|||.              :.|:|:
Mouse   493 PQQRSAGKDSSLDTDVAYLTHEGWFISDAFSEGEPASAAVDTTSQRNTSPHSEPCSSDSVSEPEC 557

  Fly   553 LIDS-------EAFLSPGHHE---------------QLKNQLQQLLQAVCHYCHERCANIVSPQS 595
            ..||       .|...||..|               :|.:.:|:||......||:|....:..::
Mouse   558 TTDSSSSKEQTSACAPPGGIEIIVSEDMRLTDLELGKLASNIQELLCNASDVCHDRAVKFLMSRA 622

  Fly   596 ----LERSSASEQELFQLSEIVDHFGETTRSICGVASVPLQLALKVQASRYAQRFHSERKQKLSL 656
                ||:.:::  |...||.:::.|...|..|||..|..|..||:.||:::..|||.||:.||||
Mouse   623 KDGFLEKLNST--EFIALSRLMETFIVDTEQICGRKSTSLLGALQSQANKFVNRFHEERRTKLSL 685

  Fly   657 LLDQERWRQVDIPHEFQRIIERMAAGDYAKPEMGNLISNGAGNP--VLLVEGKQPYTLVSASLML 719
            |||.|||:|.|:|.|||.:::.:|.|..|.||...:::. ...|  ||:|||.| |.:|...|:|
Mouse   686 LLDNERWKQADVPAEFQDLVDSIADGKIALPEKKPVVTE-ERKPADVLVVEGHQ-YAVVGTVLLL 748

  Fly   720 IRMLYEYGCSAHRLPLLASYHARNVVDLLRCFNSRSCQLIIGAGAMRVAGLKTITSTNLALVSRA 784
            ||::.||......:|.:.:.....:.|||:.||||||||::||||::|.||||||:.||||.||.
Mouse   749 IRIILEYCQCVDNIPSVTTDMLTRLTDLLKYFNSRSCQLVLGAGALQVVGLKTITTKNLALSSRC 813

  Fly   785 LQLVLWLLPKLKEHFQA---------MSGYETIERDYQGHIKEIENKIHGIVSERLAAQLDAWEA 840
            |||::..:|.::.||:|         :..::.|.:||..||.||..|:..|:.......|..:|.
Mouse   814 LQLIVHYIPVIRAHFEARLPPKQWSMLRHFDHITKDYHDHIAEISAKLVAIMDSLFDKLLSKYEV 878

  Fly   841 RPPIPSQTFRHISRHLVKLHEAIAGVLPEAQIHEIYGVVHRNFKDKLREQLLKLNVNNNGGPQHG 905
            :.|:||..||:|.:.:.|:||||..:|||.|...::..::.::|..|::||..|||.|:||||:|
Mouse   879 KAPVPSPCFRNICKQMTKMHEAIFDLLPEEQTQMLFLRINASYKLHLKKQLSHLNVINDGGPQNG 943

  Fly   906 VVTSELTFYMETLRTLKALPAEQLDNGILEEIW 938
            :||:::.||...|:.||.|....|:   :.|||
Mouse   944 LVTADVAFYTGNLQALKGLKDLDLN---MAEIW 973

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
scat	NP_524905.1	COG2	268..>418	CDD:473160	76/149 (51%)
		Vps54	708..829	CDD:462318	54/129 (42%)
		DUF4164	<810..867	CDD:433450	21/56 (38%)
Vps54	NP_620692.3	COG2	208..>331	CDD:473160	59/122 (48%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	528..573		9/44 (20%)
		Vps54	739..865	CDD:462318	52/125 (42%)