DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dek and AT3G48710

DIOPT Version :9

Sequence 1:	NP_652058.1	Gene:	Dek / 47906	FlyBaseID:	FBgn0026533	Length:	669	Species:	Drosophila melanogaster
Sequence 2:	NP_190440.1	Gene:	AT3G48710 / 824032	AraportID:	AT3G48710	Length:	462	Species:	Arabidopsis thaliana

Alignment Length:	576	Identity:	121/576 - (21%)
Similarity:	203/576 - (35%)	Gaps:	181/576 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    87 SDAAAADKKEKSPSPVIKKSNNKDAKKEDNSEKDEENSEDGDEPEDEADEKASDEESEK--KKPK 149
            :|..|..:|:            .:.||:|..||||...|.|:|.:.|..:......||:  ::.|
plant    14 ADTVAVTEKD------------TETKKKDEVEKDEAMEEKGEEIDGEKVKSPVTPVSERPIRERK 66

  Fly   150 LDAEDKIKDATDESKPKSGADKPKKPEPKAKNGKVAKEEDDDEEDEDDEDAEDDDGDENDGLDKN 214
            ......|     ::.|:|..:||.    ....|:..:
plant    67 RTGRYVI-----DTPPRSSGNKPL----SITQGRGTR---------------------------- 94

  Fly   215 NEVAEDDENVVALAEIDRINENINKTRV-DGLQTLHAICFGAQGKNNVVKKNLRSFAGFEFAKDS 278
                        |.||..:...::|.:. |.|..||.|.:|.:.|..::|||:..|:||.:::..
plant    95 ------------LKEIPNVAYKLSKRKPDDNLFLLHTILYGKKAKAQMLKKNIGQFSGFVWSEQE 147

  Fly   279 AEYNKKLEAIKKVD---NKGLRSICEILTLDRKGS---KNETVLRVLKFLMEPDESLCLEQGDEE 337
            .| .::.:|.:|:|   .:.|...|::|.:....|   |.|..:|||:||:.|..:..:...|.|
plant   148 EE-KQRAKAKEKLDKCIKEKLIDFCDVLDIPVNKSTVKKEELAVRVLEFLVCPKATRDILLADSE 211

  Fly   338 EEEDAEDEDLDEDEEDPPSEEDKKRKSGKSSGGAGRGSARNSTGRPRRATAGKKMSAYVDFSSSD 402
                               :|.||||...|                :..|:|:...
plant   212 -------------------KETKKRKKSTS----------------KNVTSGESSH--------- 232

  Fly   403 DSEQKVAVPKRRRNDDSESGSDYNPSANSDSDGGRGGGAGAAGRKVPSRGGRGRPARKSRRRNSD 467
                   ||.:||....:.........|.:||.|..|       ...|.|.......:...::.|
plant   233 -------VPAKRRRQAKKQEQPTETEGNGESDVGSEG-------TNDSNGEDDVAPEEENNKSED 283

  Fly   468 SEEEEESEVSDADSDVPKRKRGSVGKRGRPAAPASAGRRGRGRGAASRKRKDSDSEDEEVSEDEE 532
            :|.|:|.:.:...:....:||  :.||.:...||:...:.. :|:|...||.....|:..:...:
plant   284 TETEDEKDKAKEKTKSTDKKR--LSKRTKKEKPAAEEEKSI-KGSAKSSRKSFRQVDKSTTSSSK 345

  Fly   533 EEDVSDFASDQSEEERPKKSKKPITPAKNSKANNKSKPAGKADSRSK-------KSKKE------ 584
            ::.|.  ..|.|:|:...::.||  .||.||...:|:..||.:...|       |..||
plant   346 KQKVD--KDDSSKEKGKTQTSKP--QAKGSKDQGQSRKKGKKEPTRKELHVVVTKILKEVDFNTA 406

  Fly   585 -------------------------------SSEEDDDVDDKDESDEDEPLTKKGK 609
                                           .:|..||.|:|:|..|||. .|:||
plant   407 TLSDILRKLGSHFGIDLMHRKAEVKDIITDAINEMSDDDDEKEEDTEDEG-EKEGK 461

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dek	NP_652058.1	RR_TM4-6	<70..>150	CDD:283990	16/64 (25%)
		SAP	288..322	CDD:128789	11/39 (28%)
		DEK_C	615..667	CDD:285919
AT3G48710	NP_190440.1	PTZ00108	<236..396	CDD:240271	38/173 (22%)
AT3G48710	NP_190440.1	DEK_C	385..438	CDD:400903	4/52 (8%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	108	1.000	Domainoid score	I2148
eggNOG	1	0.900	-	-		E1_KOG2266
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	116	1.000	Inparanoid score	I2018
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004773
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR13468
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3357
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	9	8.920