Protein Alignment l(2)03659 and NFT1

DIOPT Version :10

• Sequence 1: NP_610482.3
• Gene: l(2)03659 / 47905
• FlyBaseID: FBgn0010549
• Length: 1374
• Species: Drosophila melanogaster
• Sequence 2: NP_013029.3
• Gene: NFT1 / 853978
• SGDID: S000001811
• Length: 1218
• Species: Saccharomyces cerevisiae
• Alignment Length: 1064
• Identity: 266/1064 - (25%)
• Similarity: 465/1064 - (43%)
• Gaps: 206/1064 - (19%)

  Fly    63 ENCKQKLTVNSENNSAQNEKEKVLPENPRARSNFISSLCFWYTIPIFRKGYRKTLDSTDLYRPLE 127
            |..:....|.:||        |.||..|    .....|.|.....:..|.|:..|.:.|:: .|:
Yeast   227 EGTRYSFLVENEN--------KKLPPAP----TVFGLLTFSRIDRLIWKAYKHCLGNADIW-DLD 278

  Fly   128 EQKSDILGNRLCASWERELKNDGRSPSLVRALLRVFGWQLGFPGLAIFVVELGLRTLQPIFLVKL 192
            .....|   .:.|::|...|.....|:::.....||..||....::.|     |..:..:.:.::
Yeast   279 INNKSI---AILANFEMSSKKGRLLPNIICYFKAVFISQLFLAFVSSF-----LNFVPSLLMPRI 335

  Fly   193 ISYFSGEPDAANAGFYYAVAQIVISALTVMILTPTTFGIHHVC------------FKMRVAMGSM 245
            :||.: :|.:.:    :.:..:.:|::.|..:..||      |            .::|..:.|.
Yeast   336 LSYVN-DPKSKS----WNLVSLYVSSMLVSKIIATT------CRGQGLFLGEKGTMQLRTVLISN 389

  Fly   246 IFRKALRLTKGALGDTTS-----------------------------GHVVNLISNDIPRLDSAP 281
            |:.|.||.|  .|.|:|:                             ..|.|::|.|..::..|.
Yeast   390 IYSKTLRRT--ILKDSTTSLQKNASTSFEENPDSSEAEPRKKSSRKDNSVNNVMSIDAFKVSEAM 452

  Fly   282 YTVHYLWVGPLQVLVITYLMYQEIGISAVFGVLFMLLFMPIQMYLGTRTSAIQLKAAERTDNRIR 346
            .|.:.........:....::|..:|.||..|...:|..:|:..:..|.....|......||.|..
Yeast   453 NTFYLACEAVFMTVTALMILYSLLGWSAFAGTFALLAMIPLNFWCATFYGNYQADQLILTDKRTS 517

  Fly   347 MVNEIISAIQVLKMYAWEQPFEQMVTHAREKEMNTIRQGQYIRGFDFARRIVLSRVAIFLSLVGY 411
            .::|.:::|:|:|:.|||..|.|.:.:.|:.|:..:::...|   .|...::.......:|.:.:
Yeast   518 GISEALNSIRVIKLLAWENLFYQKIINVRDGEIRLLKKKATI---FFLNHLIWFFGPTLVSAITF 579

  Fly   412 VIL----GKVFTPEIAFMITAYYNVLLAAMSIYVPSAIIQTAQFLTSIRRVEQFMQSEELGSSDK 472
            .:.    .:..||.|||...:.:.:|...|. .:.|.:....|...|:.|::.::...|....:.
Yeast   580 SVFIKFQNQTLTPTIAFTALSLFAILRTPMD-QIASTVSLLIQSFISLERIQDYLNESETRKYEI 643

  Fly   473 SEGPSKDTVPGNPPSNNNEADLLKSAISIRDLKAKWDPNSPDYTLSGINLEIKPGSVVAVIGLTG 537
            .|           .||        :.....|...:|:.....:.|..|:::.|..|:.|:||.||
Yeast   644 LE-----------QSN--------TKFGFEDASMEWEAAETSFKLKNISIDFKLNSLNAIIGPTG 689

  Fly   538 SGKSSLIQAILGELKANSGQLQV----------------NGSLSYTSQESWLFSGTVRQNILFGQ 586
            ||||||:..:||||...||::.|                ..|::|.||..||.|||::.|::||:
Yeast   690 SGKSSLLLGLLGELNLLSGKIYVPTVESRDDLEIGKDGMTNSMAYCSQTPWLISGTIKDNVVFGE 754

  Fly   587 PMDSQRYEEVVKKCALERDFDLLPLRDNTIVGERGATLSGGQKARISLARSVYRKASIYLLDDPL 651
            ..:.|::::|:|.|.|::|...:.....|.||:.|.:|||||:.||:|||::|..:...:|||.|
Yeast   755 IFNKQKFDDVMKSCCLDKDIKAMTAGIRTDVGDGGFSLSGGQQQRIALARAIYSSSRYLILDDCL 819

  Fly   652 SAVDASVARHLFDQCVRG-HLRGSTVVLVTHQEQFL-PHVDQIVILANGQIKALGDYESLLKTG- 713
            ||||...|.:::::|:.| .::|.|.::.:|....: ...|.:|||..|::|:.|....|:|:.
Yeast   820 SAVDPETALYIYEECLCGPMMKGRTCIITSHNISLVTKRADWLVILDRGEVKSQGKPSDLIKSNE 884

  Fly   714 -LITGLGSLSK------------TDKAKTEEQEPLNLNSPDNKNEVTPIKENSEQTVGGSSSGKE 765
             |...:.:.||            |...||:..:|...||.|   ||....||.|:|
Yeast   885 FLRESINNDSKNTTHNQIDLKRSTTSKKTKNGDPEGGNSQD---EVCAEVENFEET--------- 937

  Fly   766 HVERQESGGISLALYR---KYFQAGGGLVAFLVMLSSSVLAQVAVTGGDYFLTYWVKKESTAAGH 827
                :..|.:..:.|:   .||   |||....|..|||:|.........::|.||:...|:.
Yeast   938 ----KMEGSVKFSAYKWLADYF---GGLGVVFVFTSSSILIHGITLSQGFWLRYWLDTGSSG--- 992

  Fly   828 GEMEDMESKSMDVYKYT------LIIILSVIMNLSSSFLL-----------FNIAKKASIRLHNT 875
                   |||..:|:..      ..::..:|:.|.||||.           .|:.||...:|.::
Yeast   993 -------SKSTWLYRIVEGHSNIYFLLTYIIIGLVSSFLTSGKVWIAIISGTNVTKKIFAKLLSS 1050

  Fly   876 IFNRVTRADMHFFSINKHGSILNRFTKDMSQVDEVL---------PVVLVDVMQIALWLAGIIIV 931
            |.    .|.:.|.::...|.|:|||:|||..:|:.|         .||      :.||   ||::
Yeast  1051 IL----YAKLRFHNVTPTGRIMNRFSKDMDIIDQQLIPNFEGLSYSVV------VCLW---IILL 1102

  Fly   932 IANVNPLLLVPTLMLSVIFYHLRNLYLKTSRDLKRVEAINRSPVYSHLAASLNGLTTIRAL-DAQ 995
            |..|.|..|:..:.|..::|.:..|||:.||:|||::.||.||::...|.::.|:|||||| |.:
Yeast  1103 IGYVTPQFLLFAIPLCALYYTVCTLYLRASRELKRIDNINISPIHQLFAEAIKGVTTIRALADER 1167

  Fly   996 RVLEKEFDSYQDAHSSAFFMYIST 1019
            |.:.:...:...:::..|::.::|
Yeast  1168 RFITQSLVAIDRSNAPFFYLNMAT 1191

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
l(2)03659	NP_610482.3	PLN03130	83..1369	CDD:215595	262/1044 (25%)
NFT1	NP_013029.3	MRP_assoc_pro	252..>1218	CDD:188098	258/1027 (25%)