DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment l(2)03659 and NAP5

DIOPT Version :9

Sequence 1:	NP_001260823.1	Gene:	l(2)03659 / 47905	FlyBaseID:	FBgn0010549	Length:	1374	Species:	Drosophila melanogaster
Sequence 2:	NP_177289.1	Gene:	NAP5 / 843474	AraportID:	AT1G71330	Length:	324	Species:	Arabidopsis thaliana

Alignment Length:	328	Identity:	100/328 - (30%)
Similarity:	164/328 - (50%)	Gaps:	46/328 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   588 MDSQRYEEVVKKCALERDFDLLPLRDNTIVGERGATLSGGQKARISLARSVYRKASIYLLDDPLS 652
            ||.:||::|::.|:|.:|.::|...|.|::||||..||||||.||.:||::|:.|.|||.|||.|
plant     1 MDRERYDKVIEACSLSKDLEILSFGDQTVIGERGINLSGGQKQRIHIARALYQDADIYLFDDPFS 65

  Fly   653 AVDASVARHLFDQCVRGHLRGSTVVLVTHQEQFLPHVDQIVILANGQIKALGDYESLLKTG---- 713
            ||||....|||.:.:||.|...:|:.||||.:|||..|..:::.:|:|...|.|..:|.:|
plant    66 AVDAHTGSHLFKEALRGLLCSKSVIYVTHQVEFLPSADLTLVMKDGRISQAGKYNDILISGTDFR 130

  Fly   714 -LI----TGLGSLSKTDKAKTEEQEPLNLNSP--------DNKNEVTPIKENSEQTVGGSSSGKE 765
             ||    ..|..:...|.:...|...|:..:.        |.|.|...:|.:.   :......::
plant   131 ELIGAHQESLAVVGSADASSVSENSALDEENGVVRDDIGFDGKQESQDLKNDK---LDSGEPQRQ 192

  Fly   766 HVERQE--SGGISLALYRKYFQA--GGGLVAFLVMLSSSVLAQVAVTGGDYFLTYWVKKESTAAG 826
            .|:.:|  .|.::|.:|.||...  ||.||.|:::  ..:|.|:...|.:|::. |....|
plant   193 FVQEEERAKGSVALDVYWKYITLAYGGALVPFILL--GQILFQLLQIGSNYWMA-WATPIS---- 250

  Fly   827 HGEMEDMESKSMDVYKYTLIIILSVIMNLSSSF-------LLFNIAKKASIRLHNTIFNRVTRAD 884
                ||:::.    .|.:.::::.|.:...||.       ||.....|.:..|.:.:.:.:.|:.
plant   251 ----EDVQAP----VKLSTLMVVYVALAFGSSLCILVRATLLVTAGYKTATELFHKMHHCIFRSP 307

  Fly   885 MHF 887
            |.|
plant   308 MSF 310

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
l(2)03659	NP_001260823.1	CFTR_protein	89..1343	CDD:273530	100/328 (30%)
		ABC_membrane	171..437	CDD:294371
		ABCC_MRP_domain1	499..699	CDD:213217	53/110 (48%)
		ABC_membrane	799..1045	CDD:294371	19/96 (20%)
		ABCC_MRP_domain2	1115..1336	CDD:213211
NAP5	NP_177289.1	P-loop_NTPase	<1..112	CDD:304359	53/110 (48%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0054
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D138195at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910