Protein Alignment l(2)03659 and Abcc6

DIOPT Version :10

• Sequence 1: NP_610482.3
• Gene: l(2)03659 / 47905
• FlyBaseID: FBgn0010549
• Length: 1374
• Species: Drosophila melanogaster
• Sequence 2: NP_112275.1
• Gene: Abcc6 / 81642
• RGDID: 620268
• Length: 1502
• Species: Rattus norvegicus
• Alignment Length: 1355
• Identity: 424/1355 - (31%)
• Similarity: 681/1355 - (50%)
• Gaps: 128/1355 - (9%)

  Fly    80 NEKEKVLPENPRARSNFISSLCFWYTIPIFRKGYRKTLDSTDLYRPLEEQKSDILGNRLCASWER 144
            :|..|.|...|.|.::|.|...||:...:..|||||.|...||:....|..|:.|.::|...|.|
  Rat   200 SEDSKPLNPCPEAEASFPSKAMFWWASGLLWKGYRKLLGPKDLWSLERENSSEELVSQLEREWRR 264

  Fly   145 EL-----------------------KNDGRSPSLVRALLRVF--GWQLGFPGLAIFVVELGLRTL 184
            ..                       :...|.| |:||:.|||  .:.||...|   |:....|..
  Rat   265 NFSELPGHKGHSGMGTPETEAFLQPERSQRGP-LLRAIWRVFRSTFLLGTLSL---VISDAFRFA 325

  Fly   185 QPIFLVKLISYFSGEPDAANAGFYYAVAQIVISALTVMILTPTTFGIHHVCFKMRVAMGSMIFRK 249
            .|..|...:.:......:|..|:..||...:.:.|..:......:.:..:..::|.|:..:::||
  Rat   326 VPKLLSLFLEFMGDLESSAWTGWLLAVLMFLSACLQTLFEQQYMYRVKVLQMRLRTAITGLVYRK 390

  Fly   250 ALRLTKGALGDTTSGHVVNLISNDIPRLDSAPYTVHYLWVGPLQVLVITYLMYQEIGISAVFGVL 314
            .|.|:.|:...:.:|.||||:|.|:.||..:...::.||:..|.::|....::|.:|.||:..|.
  Rat   391 VLVLSSGSRKSSAAGDVVNLVSVDVQRLVESILHLNGLWLLFLWIIVCFVYLWQLLGPSALTAVA 455

  Fly   315 FMLLFMPIQMYLGTRTSAIQLKAAERTDNRIRMVNEIISAIQVLKMYAWEQPFEQMVTHAREKEM 379
            ..|..:|:..::..:.|..|.:...:..:|.|:.:.::..::.:|.:.||..|.:.:.|.|.:|:
  Rat   456 VFLSLLPLNFFITKKRSFHQEEQMRQKASRARLTSSMLRTVRTIKSHGWECAFLERLLHIRGQEL 520

  Fly   380 NTIRQGQYIRGFDFARRIVLSRVAIFL-SLVGYVILGKV-----FTPEIAFMITAYYNVLLAAMS 438
            ..::...::    |:..:|..:|:.|| :||.:.:...|     ...|.||:.....::|..|.:
  Rat   521 GALKTSAFL----FSVSLVSFQVSTFLVALVVFAVHTLVAEDNAMDAEKAFVTLTVLSILNKAQA 581

  Fly   439 IYVPSAIIQTAQFLTSIRRVEQFMQSEELGSSDKSEGPSKDTVPGNPPSNNNEADLLKSAISIRD 503
             ::|.::....|...|..|:..|:..||:..:.....||:.:              .|..|||.:
  Rat   582 -FLPFSVHCLVQARVSFDRLAAFLCLEEVDPNGMVLSPSRCS--------------SKDRISIHN 631

  Fly   504 LKAKWDPNSPDYTLSGINLEIKPGSVVAVIGLTGSGKSSLIQAILGELKANSGQLQVNGSLSYTS 568
            ....|...||. .|.||||.:..|.::||:|..|:|||||:.|:||||....|.:.:.||::|..
  Rat   632 GTFAWSQESPP-CLHGINLTVPQGCLLAVVGPVGAGKSSLLSALLGELLKVEGSVSIEGSVAYVP 695

  Fly   569 QESWLFSGTVRQNILFGQPMDSQRYEEVVKKCALERDFDLLPLRDNTIVGERGATLSGGQKARIS 633
            ||:|:.:.:|.:|:.|.|.:|....:||::.|||..|....|...:|.|||:|..||||||.|:|
  Rat   696 QEAWVQNTSVVENVCFRQELDLPWLQEVLEACALGSDVASFPAGVHTPVGEQGMNLSGGQKQRLS 760

  Fly   634 LARSVYRKASIYLLDDPLSAVDASVARHLFDQCV--RGHLRGSTVVLVTHQEQFLPHVDQIVILA 696
            |||:|||:|::||:||||:|:||.|::.:|.|.:  .|.|:|:|.:||||....||..|||::||
  Rat   761 LARAVYRRAAVYLMDDPLAALDAHVSQEVFKQVIGPSGLLQGTTRILVTHTLHVLPQADQILVLA 825

  Fly   697 NGQIKALGDYESLL-KTGLITGLGSLSKTDKAKTEEQEPLNLNSPD-----------------NK 743
            ||.|..:|.|:.|| :.|.:.||...::....:.|.:......|.|                 ..
  Rat   826 NGTIAEMGSYQDLLHRNGALVGLLDGARQPAGEGEGEAHAAATSDDLGGFSGGGTPTRRPERPRP 890

  Fly   744 NEVTPIKENSEQT----------VGGSSSGKEHVERQESGGISLALYRKYFQA-GGGLVAFLVML 797
            ::..|:|.::.:.          |.|.::|::.|   :.|.:..|.|..|.:| |..|..:.:.|
  Rat   891 SDAAPVKGSTSEAQMEPSLDDVEVTGLTAGEDSV---QYGRVKSATYLSYLRAVGTPLCTYTLFL 952

  Fly   798 SSSVLAQVAVTGGDYFLTYWVK------KESTAAGHGEMEDMESKSMDVYKYTLIIILSVIMNLS 856
              .:..|||.....|:|:.|..      |:..:|..|.:            :.|:..|..|...:
  Rat   953 --FLCQQVASFCQGYWLSLWADDPVVDGKQMHSALRGSI------------FGLLGCLQAIGLFA 1003

  Fly   857 SSFLLFNIAKKASIRLHNTIFNRVTRADMHFFSINKHGSILNRFTKDMSQVDEVLPVVLVDVMQI 921
            |...:|....:||..|..::...|.|:.:.||.....|::||||:|:...||..:|..:..::..
  Rat  1004 SMAAVFLGGARASCLLFRSLLWDVARSPIGFFERTPVGNLLNRFSKETDIVDVDIPDKMRTLLTY 1068

  Fly   922 ALWLAGIIIVIANVNPLLLVPTLMLSVIFYHLRNLYLKTSRDLKRVEAINRSPVYSHLAASLNGL 986
            |..|..:.:.::...||.:|..|.|.:::...::||:.|...|:|:|:.:.|.|.||||.:..|.
  Rat  1069 AFGLLEVGLAVSMATPLAIVAILPLMLLYAGFQSLYVATCCQLRRLESASYSSVCSHLAETFQGS 1133

  Fly   987 TTIRALDAQRVLEKEFDSYQDAHSSAFFMYI-------STSQAFGYCMNCICVIYISIITLSFFA 1044
            ..:||..||.....:.|:..|.:....|..:       :..:..|   |.:..:..:...||...
  Rat  1134 QVVRAFQAQGPFTAQHDALMDENQRISFPRLVADRWLAANLELLG---NGLVFVAATCAVLSKAH 1195

  Fly  1045 FPPGNGADVGLVITQAMGLIDMVQWGVRQTAELENTMTAVERVVEYESIEPEGMLEAPDDKKPPK 1109
            ...|.   .|..::.|:.:...:||.||...:|||:|.|||||.:|.....|.....|.....|
  Rat  1196 LSAGL---AGFSVSAALQVTQTLQWVVRSWTDLENSMVAVERVQDYVHTPKEAPWRLPSSAAQP- 1256

  Fly  1110 TWPEQGEIIFKELNLRYTPNAKAENVLKSLSFVIQPREKVGIVGRTGAGKSSLINALFRL-SYTD 1173
            .||..|:|.|::..||:.|  :....::.:|..|...||||||||||||||||...|.|| ..|:
  Rat  1257 LWPCGGQIEFRDFGLRHRP--ELPMAVQGVSLKIHAGEKVGIVGRTGAGKSSLTWGLLRLQEATE 1319

  Fly  1174 GSVLIDTRDTRQMGLHDLRRQISIIPQEPVLFSGTMRYNLDPFDEYSDEKLWGCLEEVKLKEVVS 1238
            |.:.||......||||.||.:|:||||:||||.|::|.|||...|.:||.:|..||.|:||..|:
  Rat  1320 GGIWIDGVPITDMGLHTLRSRITIIPQDPVLFPGSLRMNLDLLQENTDEGIWAALETVQLKAFVT 1384

  Fly  1239 DLPDGLASKISEGGTNFSVGQRQLVCLARAILRENRILVMDEATANVDPQTDGLIQATIRSKFRD 1303
            .||..|..:.|..|.:.||||:||:|||||:||:.:||::|||||:|||.|:..:||.:...|..
  Rat  1385 SLPGQLQYECSGQGDDLSVGQKQLLCLARALLRKTQILILDEATASVDPGTEIQMQAALERWFAQ 1449

  Fly  1304 CTVLTIAHRLHTIIDSDKVMVMDAGRVVEFGSPYELMTKSDSKVFHNLVNQSGRA 1358
            ||||.|||||.::::..:|:|||.|:|.|.|||.:|:.:..  :|:.|..:||.|
  Rat  1450 CTVLLIAHRLRSVMNCARVLVMDEGQVAESGSPAQLLAQKG--LFYRLAQESGLA 1502

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
l(2)03659	NP_610482.3	PLN03130	83..1369	CDD:215595	423/1352 (31%)
Abcc6	NP_112275.1	MRP_assoc_pro	36..1501	CDD:188098	422/1352 (31%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	854..909		5/54 (9%)