| Sequence 1: | NP_001260823.1 | Gene: | l(2)03659 / 47905 | FlyBaseID: | FBgn0010549 | Length: | 1374 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001028508.2 | Gene: | Abcc4 / 239273 | MGIID: | 2443111 | Length: | 1325 | Species: | Mus musculus |
| Alignment Length: | 1323 | Identity: | 553/1323 - (41%) |
|---|---|---|---|
| Similarity: | 833/1323 - (62%) | Gaps: | 81/1323 - (6%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 89 NPRARSNFISSLCFWYTIPIFRKGYRKTLDSTDLYRPLEEQKSDILGNRLCASWEREL---KNDG 150
Fly 151 RSPSLVRALLRVFGWQLGFPGLAIF-VVELGLRTLQPIFLVKLISYFSG-EPD---AANAGFYYA 210
Fly 211 VAQIVISALTVMILTPTTFGIHHVCF--------KMRVAMGSMIFRKALRLTKGALGDTTSGHVV 267
Fly 268 NLISNDIPRLDSAPYTVHYLWVGPLQVLVITYLMYQEIGISAVFGVLFMLLFMPIQMYLGTRTSA 332
Fly 333 IQLKAAERTDNRIRMVNEIISAIQVLKMYAWEQPFEQMVTHAREKEMNTIRQGQYIRGFDFARRI 397
Fly 398 VLSRVAIFLSLVGYVILGKVFTPEIAFMITAYYNVLLAAMSIYVPSAIIQTAQFLTSIRRVEQFM 462
Fly 463 QSEELGSSDKSEGPSKDTVPGNPPSNNNEADLLKSAISIRDLKAKWDPNSPDYTLSGINLEIKPG 527
Fly 528 SVVAVIGLTGSGKSSLIQAILGELKANSGQLQVNGSLSYTSQESWLFSGTVRQNILFGQPMDSQR 592
Fly 593 YEEVVKKCALERDFDLLPLRDNTIVGERGATLSGGQKARISLARSVYRKASIYLLDDPLSAVDAS 657
Fly 658 VARHLFDQCVRGHLRGSTVVLVTHQEQFLPHVDQIVILANGQIKALGDYESLLKTGLITGLGSLS 722
Fly 723 KTDKAKTEEQEPLNLNSPDNKNEVT--------------PIKENSEQTVGGSSSGKEHVERQES- 772
Fly 773 --GGISLALYRKYFQAGGG--LVAFLVMLSSSVLAQVAVTGGDYFLTYWVKKE----STAAGHGE 829
Fly 830 MEDMESKSMDVYKYTLIIILSVIMNLSSSFLLFNIAKKASIRLHNTIFNRVTRADMHFFSINKHG 894
Fly 895 SILNRFTKDMSQVDEVLPVVLVDVMQIALWLAGIIIVIANVNPLLLVPTLMLSVIFYHLRNLYLK 959
Fly 960 TSRDLKRVEAINRSPVYSHLAASLNGLTTIRALDAQRVLEKEFDSYQDAHSSAFFMYISTSQAFG 1024
Fly 1025 YCMNCICVIYISIITL-SFFAFPPGNGADVGLVITQAMGLIDMVQWGVRQTAELENTMTAVERVV 1088
Fly 1089 EYESIEPEGMLEAPDDKKPPKTWPEQGEIIFKELNLRYTPNAKAENVLKSLSFVIQPREKVGIVG 1153
Fly 1154 RTGAGKSSLINALFRLSYTDGSVLIDTRDTRQMGLHDLRRQISIIPQEPVLFSGTMRYNLDPFDE 1218
Fly 1219 YSDEKLWGCLEEVKLKEVVSDLPDGLASKISEGGTNFSVGQRQLVCLARAILRENRILVMDEATA 1283
Fly 1284 NVDPQTDGLIQATIRSKFRDCTVLTIAHRLHTIIDSDKVMVMDAGRVVEFGSPYELMTKSDSKVF 1348
Fly 1349 HNLVNQSGRASYEGLLKIAQETF 1371 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| l(2)03659 | NP_001260823.1 | CFTR_protein | 89..1343 | CDD:273530 | 546/1293 (42%) |
| ABC_membrane | 171..437 | CDD:294371 | 102/278 (37%) | ||
| ABCC_MRP_domain1 | 499..699 | CDD:213217 | 103/199 (52%) | ||
| ABC_membrane | 799..1045 | CDD:294371 | 91/250 (36%) | ||
| ABCC_MRP_domain2 | 1115..1336 | CDD:213211 | 142/220 (65%) | ||
| Abcc4 | NP_001028508.2 | PLN03130 | 12..1284 | CDD:215595 | 550/1312 (42%) |
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 657..690 | 3/34 (9%) | |||
| PDZ-binding. /evidence=ECO:0000250|UniProtKB:O15439 | 1322..1325 | ||||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 1 | 0.930 | - | - | C167841683 | |
| Domainoid | 1 | 1.000 | 232 | 1.000 | Domainoid score | I2403 |
| eggNOG | 1 | 0.900 | - | - | E2759_KOG0054 | |
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 1 | 1.000 | - | - | H74563 | |
| Inparanoid | 1 | 1.050 | 1109 | 1.000 | Inparanoid score | I229 |
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 1 | 1.010 | - | - | QHG51855 | |
| OrthoDB | 1 | 1.010 | - | - | D138195at2759 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0001028 | |
| OrthoInspector | 1 | 1.000 | - | - | otm42331 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_100026 | |
| Panther | 1 | 1.100 | - | - | O | PTHR24223 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 1 | 1.000 | - | - | X771 | |
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| 14 | 13.810 | |||||