Protein Alignment l(2)03659 and haf-4

DIOPT Version :9

• Sequence 1: NP_001260823.1
• Gene: l(2)03659 / 47905
• FlyBaseID: FBgn0010549
• Length: 1374
• Species: Drosophila melanogaster
• Sequence 2: NP_001021666.1
• Gene: haf-4 / 171639
• WormBaseID: WBGene00001814
• Length: 787
• Species: Caenorhabditis elegans
• Alignment Length: 555
• Identity: 141/555 - (25%)
• Similarity: 263/555 - (47%)
• Gaps: 83/555 - (14%)

  Fly   840 VYKYTLIIILSVIMN--LSSSFLLFNIAKKASIRLHNTI----FNRVTRADMHFFSINKHGSILN 898
            ||..|:|.::|.:..  ...||      :.|..|:...|    |:.:.:.|:.|:..:|.|.:.:
 Worm   223 VYIMTIISLVSAVAAGFRGGSF------EYAYARIQRAIRYDLFHGLVKQDVAFYDAHKTGEVTS 281

  Fly   899 RFTKDMSQVDEVLPVVLVDVMQIALWLAGIIIVIANVN------PLLLVPTLML-SVIFYHLRNL 956
            |...|...:.:.:.:.:...::..:.|.|.:|.:..::      ..:|||.:.: |.||....:|
 Worm   282 RLAADCQTMSDTVALNVNVFLRNCVMLLGSMIFMMKLSWRLSLVTFILVPIIFVASKIFGTYYDL 346

  Fly   957 YLKTSRDLKRVEAINRSPVYSHLAAS-------LNGLTTIRALDAQRVLEKEFDSYQD--AHSSA 1012
            ..:.::|.              :|.|       |:.:.|:|:...:.|   |.|.:..  .|:
 Worm   347 LSERTQDT--------------IAESNDVAEEVLSTMRTVRSFSCENV---EADRFYGKLTHT-- 392

  Fly  1013 FFMYISTSQAFGYCMNCICVIYISIITLSFF----AFPPGNGADVGLVITQAMG-------LIDM 1066
              :.::.::|..|    |..:::|.:..||.    .:..|:     ||:||.|.       |:..
 Worm   393 --LDVTRTKAIAY----IGFLWVSELFQSFIIVSVLWYGGH-----LVLTQKMKGDLLVSFLLYQ 446

  Fly  1067 VQWG--VRQTAE----LENTMTAVERVVEYESIEPEGMLEAPDDKKPPKTWPEQGEIIFKELNLR 1125
            :|.|  :||..|    |..::.|..:|.||...||:  ::...:..|...   .|:|.|:.::..
 Worm   447 MQLGDNLRQMGEVWTGLMQSVGASRKVFEYIDREPQ--IQHNGEYMPENV---VGKIEFRNVHFS 506

  Fly  1126 YTPNAKAENVLKSLSFVIQPREKVGIVGRTGAGKSSLINALFRLSYTD-GSVLIDTRDTRQMGLH 1189
            | |....:.:||.|||.::|.|.|.:||.:|:||||.|:.|......: |.||:|.....:...|
 Worm   507 Y-PTRSDQPILKDLSFTVEPGETVALVGPSGSGKSSCISLLENFYVPNAGQVLVDGVPLEEFEHH 570

  Fly  1190 DLRRQISIIPQEPVLFSGTMRYNLDPFDEYSDEKLWGCLEEVKLKEVVSDLPDGLASKISEGGTN 1254
            .:.::|:::.||||||:.::..|:....|.:|.::....|.......:........:.:.|.||.
 Worm   571 YIHKKIALVGQEPVLFARSVMENVRYGVEVADTEIIRSCEMANAHGFIMQTTLKYETNVGEKGTQ 635

  Fly  1255 FSVGQRQLVCLARAILRENRILVMDEATANVDPQTDGLIQATIRSKFRDCTVLTIAHRLHTIIDS 1319
            .|.||:|.:.:|||::||..||::||||:.:|.:::.|:|..|.......:|:.|||||.|:..:
 Worm   636 MSGGQKQRIAIARALVREPAILLLDEATSALDTESEHLVQEAIYKNLDGKSVILIAHRLSTVEKA 700

  Fly  1320 DKVMVMDAGRVVEFGSPYELMTKSDSKVFHNLVNQ 1354
            ||::|::.|||.:.|: :|.:.|..:..:..||.:
 Worm   701 DKIVVINKGRVEQIGN-HETLLKDTNGTYAKLVQR 734

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
l(2)03659	NP_001260823.1	CFTR_protein	89..1343	CDD:273530	138/542 (25%)
		ABC_membrane	171..437	CDD:294371
		ABCC_MRP_domain1	499..699	CDD:213217
		ABC_membrane	799..1045	CDD:294371	43/230 (19%)
		ABCC_MRP_domain2	1115..1336	CDD:213211	74/221 (33%)
haf-4	NP_001021666.1	3a01208	16..732	CDD:273363	139/551 (25%)
		ABC_membrane	189..449	CDD:279056	50/261 (19%)
		ABC_MTABC3_MDL1_MDL2	498..735	CDD:213216	77/239 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910