Protein Alignment l(2)03659 and Abcc2

DIOPT Version :10

• Sequence 1: NP_610482.3
• Gene: l(2)03659 / 47905
• FlyBaseID: FBgn0010549
• Length: 1374
• Species: Drosophila melanogaster
• Sequence 2: NP_038834.2
• Gene: Abcc2 / 12780
• MGIID: 1352447
• Length: 1543
• Species: Mus musculus
• Alignment Length: 1406
• Identity: 481/1406 - (34%)
• Similarity: 738/1406 - (52%)
• Gaps: 203/1406 - (14%)

  Fly    90 PRARSNFISSLCF-WYTIPIFRKGYRKTLDSTDLYRPLEEQKSDILGNRLCA-----------SW 142
            |.|.::|:||:.| ||...:. |||:..|...|::...|..|:..|.::...           :.
Mouse   193 PSATASFLSSVTFSWYDSTVL-KGYKHPLTIEDVWDIEENLKAKSLTSKFKTIMTKDLQKARQAL 256

  Fly   143 ERELKNDGRSPS---------------------------------------LVRALLRVFGWQLG 168
            :|.||...:||.                                       ||:||.:.|...:
Mouse   257 QRRLKKSQQSPEGTSHGLTKKQSQSQDVLVLEDSKKKKKKSEATKDFPKSWLVKALFKTFYVVI- 320

  Fly   169 FPGLAIFVVELG---LRTLQPIFLVKLISYFSGEPDAAN-AGFYYAVAQIVISALTVMILTPTTF 229
               |..|:::|.   |..|.| .|:|.:..|..:||:.. .|:.||:....::.:....|.
Mouse   321 ---LKSFILKLAHDILLFLNP-QLLKFLIGFVKDPDSYPWVGYIYAILMFSVTLIQSFFLQ---- 377

  Fly   230 GIHHVCF----KMRVAMGSMIFRKALRLTKGALGDTTSGHVVNLISNDIPRLDSAPYTVHYLWVG 290
            .....||    .:|..:.:.:::|||.|:..|....|.|..|||:|.|..:|......:|.||..
Mouse   378 CYFQFCFVLGMTVRTTIIASVYKKALTLSNLARRQYTIGETVNLMSVDSQKLMDVTNYIHLLWSS 442

  Fly   291 PLQVLVITYLMYQEIGISAVFGVLFMLLFMPIQMYLGTRTSAIQLKAAERTDNRIRMVNEIISAI 355
            .||:.:..:.:::|:|.|.:.||..|:|.:|:...|.|:...||::..:..|.|::::|||:|.|
Mouse   443 VLQIALSIFFLWRELGPSILAGVGLMVLLVPVNGVLATKIRKIQVQNMKNKDKRLKIMNEILSGI 507

  Fly   356 QVLKMYAWEQPFEQMVTHAREKEM-NTIRQGQYIRGFDFARRIVLSRVAIFLSLVGYVILG--KV 417
            ::||.:|||..|::.|...|:||: |.:|..|......|...:..:.|::....| ||::.  .|
Mouse   508 KILKYFAWEPSFKEQVNSIRKKELRNLLRFSQLQTILIFILHLTPTLVSVITFSV-YVLVDSQNV 571

  Fly   418 FTPEIAFMITAYYNVLLAAMSIYVPSAIIQTAQFLTSIRRVEQFMQSEELGSS--------DKSE 474
            ...|.||.....:|:|...::: :|..|....|...|:.|:||::.|::|..|        ||
Mouse   572 LNAEKAFTSITLFNILRFPLAM-LPMVISSVIQASVSVDRLEQYLGSDDLDLSAIRHVCHFDK-- 633

  Fly   475 GPSKDTVPGNPPSNNNEADLLKSAISIRDLKAKWDPNSPDYTLSGINLEIKPGSVVAVIGLTGSG 539
                                   |:...:....|| ...:.|:..:||:||||.:|||:|..|||
Mouse   634 -----------------------AVQFSEASFTWD-RDLEATIQDVNLDIKPGQLVAVVGTVGSG 674

  Fly   540 KSSLIQAILGELKANSGQLQVNGSLSYTSQESWLFSGTVRQNILFGQPMDSQRYEEVVKKCALER 604
            |||||.|:|||::...|.:.:.||::|..|::|:.:||::.|||||...|.::|:.|::.|||..
Mouse   675 KSSLISAMLGEMENVHGHITIKGSIAYVPQQAWIQNGTIKDNILFGSEYDEKKYQRVIEACALLP 739

  Fly   605 DFDLLPLRDNTIVGERGATLSGGQKARISLARSVYRKASIYLLDDPLSAVDASVARHLFDQCV-- 667
            |.::||..|...:||:|..||||||.|:||||:.|:.|.||:|||||||||..|.:|:|::.|
Mouse   740 DLEMLPGGDMAEIGEKGINLSGGQKHRVSLARATYQDADIYILDDPLSAVDTHVGKHIFNKVVGP 804

  Fly   668 RGHLRGSTVVLVTHQEQFLPHVDQIVILANGQIKALGDYESLL-KTGLI----------TGLGSL 721
            .|.|.|.|.:||||...|||.||:||:|..|.|...|.|..|: |.|:.          :|....
Mouse   805 NGLLSGKTRILVTHGIHFLPQVDEIVVLGKGTILEKGSYSDLMDKKGVFAKNWKTFMKHSGPEGE 869

  Fly   722 SKTDKAKTEEQEPLNL-----NSPDNKNEVTPIKENS-EQTVGGSS-SG---------------- 763
            :..|....||.....|     ..||:...:|..:||| .:|:..|| ||
Mouse   870 ATVDNDSEEEDGDCGLIPTVEEIPDDAASLTMRRENSLRRTLSRSSRSGSRRGKSLKSSLKIKSV 934

  Fly   764 -----KEHV---------ERQESGGISLALYRKYFQA-GGGLVAFLVMLSSSVLAQVAVTGGDYF 813
                 ||.|         |..|:|.:..::|.||.|| |...:.|:|:.  .||..||..|.:.:
Mouse   935 NALNKKEEVVKGQKLIKKEFVETGKVKFSIYLKYLQAVGWWSLLFIVIF--YVLNYVAFIGTNLW 997

  Fly   814 LTYWVKKESTAAGHGEMEDMESKSMDVYKYTLIIILSVIMNLSSSFLLFNIAKKASIRLHNTIFN 878
            |:.|.  ..:...:|.......:.|.:..:..:.|...|..||||.......:.||..||..:..
Mouse   998 LSAWT--SDSEKQNGTDNSPSQRDMRIGVFGALGIAQGIFLLSSSLWSIYACRNASKTLHRQLLT 1060

  Fly   879 RVTRADMHFFSINKHGSILNRFTKDMSQVDEVLPVVLVDVMQIALWLAGIIIVIANVNPLLLVPT 943
            .:.||.|.||.....|.|:|||..|:|.||:.||..|...:.....:...:::|....|:.::..
Mouse  1061 NILRAPMSFFDTTPTGRIVNRFAGDISTVDDTLPQTLRSWLLCFFGIVSTLVMICMATPIFIIII 1125

  Fly   944 LMLSVIFYHLRNLYLKTSRDLKRVEAINRSPVYSHLAASLNGLTTIRALD-AQRVL---EKEFDS 1004
            :.||:::..::..|:.|||.|:|::::.:||:|||.:.:::||..|||.: .||.|   ||:.|:
Mouse  1126 IPLSILYVSVQVFYVATSRQLRRLDSVTKSPIYSHFSETVSGLPVIRAFEHQQRFLANSEKQIDT 1190

  Fly  1005 YQDAHSSAFFMYISTSQAFG-----------YCMNCICVIYISIITLSFFAFPPGNGADVGLVIT 1058
            .|    ...|.:|::::...           :|...:.|||.:.:|          |..||.|::
Mouse  1191 NQ----KCVFSWITSNRWLAIRLELVGNLIVFCSALLLVIYKNSLT----------GDTVGFVLS 1241

  Fly  1059 QAMGLIDMVQWGVRQTAELENTMTAVERVVEYESIEPEGMLEAP--DDKKPPKTWPEQGEIIFKE 1121
            .|:.:...:.|.||.|:|:|..:.||||:.||.:::.    |||  .|||||..||::|||.|..
Mouse  1242 NALNITQTLNWLVRMTSEVETNIVAVERINEYINVDN----EAPWVTDKKPPADWPKKGEIQFNN 1302

  Fly  1122 LNLRYTPNAKAENVLKSLSFVIQPREKVGIVGRTGAGKSSLINALFR-LSYTDGSVLIDTRDTRQ 1185
            ..:||.|  :.:.|||.::..|:..||||:|||||||||||.|.||| |....|.::||..|...
Mouse  1303 YQVRYRP--ELDLVLKGITCNIKSTEKVGVVGRTGAGKSSLTNCLFRILESAGGQIIIDGIDIAS 1365

  Fly  1186 MGLHDLRRQISIIPQEPVLFSGTMRYNLDPFDEYSDEKLWGCLEEVKLKEVVSDLPDGLASKISE 1250
            :||||||.:::||||:|:||||.:|.|||||::||||::|..||...||..|:.|..||..:::|
Mouse  1366 IGLHDLRGRLTIIPQDPILFSGNLRMNLDPFNKYSDEEIWRALELAHLKSFVAGLQLGLLHEVTE 1430

  Fly  1251 GGTNFSVGQRQLVCLARAILRENRILVMDEATANVDPQTDGLIQATIRSKFRDCTVLTIAHRLHT 1315
            ||.|.|:|||||:||.||:||:::|||:|||||.||.:||.|||.|||::|..|||:||||||||
Mouse  1431 GGDNLSIGQRQLLCLGRAVLRKSKILVLDEATAAVDLETDSLIQTTIRNEFSQCTVITIAHRLHT 1495

  Fly  1316 IIDSDKVMVMDAGRVVEFGSPYELMTKSDSKVFHNLVNQSG 1356
            |:||||:||:|:|::||:|||.||:  |:...|:.:..::|
Mouse  1496 IMDSDKIMVLDSGKIVEYGSPEELL--SNMGPFYLMAKEAG 1534

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
l(2)03659	NP_610482.3	PLN03130	83..1369	CDD:215595	481/1406 (34%)
Abcc2	NP_038834.2	MRP_assoc_pro	10..1535	CDD:188098	481/1406 (34%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	260..285		4/24 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	903..927		8/23 (35%)